STRUCTURAL CHARACTERIZATION OF A NOVEL LOW-SPIN ALKYLPEROXO-IRON(III) COMPLEX

新型低自旋烷基过氧铁(III)络合物的结构表征

• 批准号: 8170050
• 负责人: James E. Penner-Hahn
• 金额: $ 0.03万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170050
• 关键词: Complex; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Heme; Institution; Iron; Ligands; Ligation; Measurement; Peroxides; Research; Research Personnel; Resources; Role; Site; Source; Structure; United States National Institutes of Health; novel; oxidation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Goldberg an co-workers have recently prepared a novel low-spin non-heme peroxo complex(Krishnamurthy et al., in press). Vibrational spectra for the complex confirm the presence of an ironbound peroxide with unusually weak Fe-O and O-O bonsd, and UV-visible spectra suggest that the Fe oxidation state is best described as Fe(III). These measurements are unable to define the Fe ligation. In order to define the structure of the complex, and thus establish the understand its role as a mimic for bioinorganic sites, we need to determine whether a pendant thiolate ligand remains coordinated to the Fe. We will use EXAFS to define this structure.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 戈德堡（Goldberg）的同事们最近制作了一种新型的低自旋非血红素过氧络合物（Krishnamurthy等人，印刷中）。该复合物的振动光谱证实了具有异常弱的Fe-O和O-O BONSD的过氧化铁的存在，并且紫外可见的光谱表明Fe氧化态最好地描述为Fe（III）。这些测量结果无法定义FE结扎。为了定义复合物的结构，从而确定其作为生物无机部位的模仿作用的理解，我们需要确定是否吊坠硫醇酸盐配体是否仍与FE协调。我们将使用EXAF来定义此结构。