Administrative Core

行政核心

• 批准号: 10016226
• 负责人: Kai Tan
• 金额: $ 34.37万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10016226
• 关键词: Administrator; Atlases; Bioinformatics; Budgets; Cancer Biology; Clinical Oncology; Data Coordinating Center; Decision Making; Discipline; Ensure; Funding; Genomics; Human; Hunger; Monitor; Office of Administrative Management; Pediatric Neoplasm; Program Research Project Grants; Recording of previous events; Regulation; Reporting; Research; Research Personnel; Resources; Risk; Schedule; Systems Biology; Time; Tissues; United States National Institutes of Health; anticancer research; cancer clinical trial; data resource; data sharing; experience; flexibility; meetings; neoplastic cell; operation; programs; single cell technology; statistics; tumor

Abstract The specific aims of our Center require diverse experts who interact closely and bring complementary expertise to the project. We have assembled a group of investigators that span the necessary sub-disciplines and have a history of working together. The Administrative core of the Center for Pediatric Tumor Cell Atlas (CPTCA) will be co-led by Dr. Tan and Dr. Hunger. Administrative oversight of the Center will be provided by an internal Executive Committee. The daily operation will be managed by a dedicated Center Administrator. The Executive Committee has extensive experience in various aspects of tumor atlas construction, including organizing multicomponent program project grants, clinical oncology, clinical trials, cancer biology, genomics, single-cell technologies, statistics, bioinformatics, and systems biology. The Executive Committee will be advised in its decision making by an Internal Advisory Board (IAB) and an External Advisory Board (EAB). The Administrative Core will support the administrative management and research coordination of the CPTCA via the following five specific aims: 1) To optimize interactions among Center investigators through regularly scheduled meetings; 2) To facilitate interactions with other Human Tumor Atlas Network (HTAN) research centers, the HTAN data coordinating center, the HTAN tissue coordination center, and NCI; 3) To ensure timely reporting to NIH and compliance with NIH regulations regarding sharing of data and resources; 4) To solicit, fund, and monitor collaborative projects; and 5) To support enrichment programs for single-cell technologies in cancer research. Risk will be mitigated through flexible planning and progress review, including shifting budgets and resources. The IAB, EAB, and the HTAN steering committee will be used to guide planning.

抽象的 我们中心的具体目标需要不同的专家密切互动并带来 项目的补充专业知识。我们召集了一组调查员 它们跨越了必要的子学科，并且有着合作的历史。这 儿科肿瘤细胞图谱中心（CPTCA）的行政核心将由共同领导 作者：Tan 博士和 Hunger 博士。该中心的行政监督将由 内部执行委员会。日常运作将由专人负责管理 中心管理员。执行委员会在各方面拥有丰富的经验 肿瘤图谱构建的各个方面，包括组织多部分程序 项目资助、临床肿瘤学、临床试验、癌症生物学、基因组学、单细胞 技术、统计学、生物信息学和系统生物学。执行委员会 内部顾问委员会 (IAB) 和 外部顾问委员会 (EAB)。行政核心将支持行政 CPTCA的管理和研究协调通过以下五个具体方面 目标： 1) 通过定期优化中心研究人员之间的互动 预定的会议； 2) 促进与其他人类肿瘤图谱网络的互动 (HTAN) 研究中心、HTAN 数据协调中心、HTAN 组织 协调中心和 NCI； 3）确保及时向NIH报告并遵守 NIH 关于数据和资源共享的规定； 4) 征集、资助和监督 合作项目； 5) 支持单细胞富集计划 癌症研究技术。通过灵活的规划和实施可以降低风险 进度审查，包括调整预算和资源。 IAB、EAB 和 HTAN 指导委员会将用于指导规划。