Text Messaging to Improve Hypertension Medication Adherence in African Americans

通过短信提高非裔美国人的高血压药物依从性

• 批准号: 7979909
• 负责人: Lorraine R Buis
• 金额: $ 17.23万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7979909
• 关键词: Text; Messaging; Improve; Hypertension; Medication

DESCRIPTION (provided by applicant): Uncontrolled high blood pressure (HBP) is a major public health concern and leading cause of cardiovascular disease worldwide. The HBP crisis is particularly onerous to African Americans as they are disproportionately more susceptible to HBP than non-Hispanic White Americans. Poor adherence to prescribed medication regimens is a major problem, as only about half of patients who have been diagnosed with hypertension adhere to prescribed medications. Mobile phones and text messages are becoming widely integrated into routine daily life and may offer a simple and non-labor intensive strategy for improving the quality of medication management through enhancing medication adherence. This proposed research will be conducted in two distinct phases addressing three specific aims. For Specific Aim 1 (Phase I), we propose to conduct focus groups with participants from our target population in order to obtain feedback to guide the development of a mobile phone text message system that seeks to improve adherence to antihypertensive medications. For Specific Aim 2 (Phase II), we propose to pilot test the newly developed text message intervention with a randomized controlled trial. For Specific Aim 3 (Phase II), we propose to ascertain participant perceptions of intervention effectiveness and satisfaction in order to guide further system refinement. In Phase I, African Americans with uncontrolled hypertension (n=24-32) will be recruited to take part in one of four focus groups that will help guide the development of the text message intervention. In Phase II, African Americans with uncontrolled hypertension will be randomized to receive usual care (n=30) vs. the text message intervention (n=30). The primary outcome in this pilot will be change in medication adherence at one month follow-up; secondary outcomes include change in medication self-efficacy and systolic and diastolic blood pressure at one month follow-up, as well as participant satisfaction with the text message intervention. The proposed research will utilize the Wayne State University (WSU) Center for Urban Studies to conduct high quality and professionally run focus groups, the WSU Division of Computing and Information Technology's Broadcast Message Service infrastructure for the delivery of text messages, the WSU Center for Health Research for statistical analysis and grant management assistance, and a diverse study team from a variety of disciplinary backgrounds at WSU. As a result, the proposed research leverages the considerable local resources to investigate an innovative and much needed intervention for this high-risk population. PUBLIC HEALTH RELEVANCE: Poor adherence to prescribed medication regimens is a major problem, particularly among African Americans with uncontrolled high blood pressure. Mobile phones and text messages may offer a simple and non-labor intensive strategy for enhancing medication adherence. Due to its reliance on technologies already adopted by individuals, this application seeks to develop and test an innovative, adaptable, and highly scalable text message intervention for improving medication adherence in our target population.

描述（由申请人提供）：不受控制的高血压（HBP）是全球的主要公共卫生问题，也是引起心血管疾病的主要原因。 HBP危机对非裔美国人特别繁重，因为他们比非西班牙裔美国人更容易受到HBP的影响。对处方药方案的依从性不佳是一个主要问题，因为只有一半被诊断出患有高血压的患者遵守处方药。手机和短信正被广泛整合到常规日常生活中，并可能提供一种简单且非劳动密集型的策略，通过增强药物依从性来改善药物管理的质量。这项拟议的研究将以两个不同的阶段进行，以解决三个具体目标。对于特定的目标1（I阶段），我们建议与目标人群的参与者进行焦点小组，以获得反馈，以指导手机文本消息系统的开发，该消息旨在提高依从性对降压药物的依从性。对于特定目标2（II阶段），我们建议通过随机对照试验测试新开发的文本消息干预措施。对于特定的目标3（II阶段），我们建议确定参与者对干预效率和满意度的看法，以指导进一步的系统改进。在第一阶段，将招募患有不受控制的高血压（n = 24-32）的非裔美国人参加四个焦点小组之一，这将有助于指导文本消息干预的发展。在第二阶段，非洲裔美国人将随机分配不受控制的高血压（n = 30）与文本消息干预（n = 30）。该试点的主要结果将是在一个月随访中的药物依从性变化；次要结果包括一个月随访的药物自我效能感以及收缩压和舒张压的变化，以及参与者对文本消息干预的满意度。拟议的研究将利用韦恩州立大学（WSU）城市研究中心进行高质量和专业运行焦点小组，计算机和信息技术的WSU部门的广播信息服务基础架构，用于提供文本消息，WSU健康研究中心的统计分析和赠款分析中心和赠款管理协助的研究中心，以及来自各种院士背景的多元化研究团队。结果，拟议的研究利用了大量的当地资源来研究这种高风险人群的创新且急需的干预措施。 公共卫生相关性：对处方药方案的依从性不佳是一个主要问题，尤其是在高血压不受控制的非裔美国人中。手机和短信可能会提供一种简单而非劳动的密集型策略来增强药物依从性。由于其依赖个人已经采用的技术，因此该应用程序旨在开发和测试一种创新，适应性且高度可扩展的文本消息干预措施，以改善我们目标人群的药物依从性。