Training Program in Quantitative Biology and Physiology

定量生物学和生理学培训计划

• 批准号: 7890952
• 负责人: EDWARD DAMIANO
• 金额: $ 26.11万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7890952
• 关键词: Biology; Physiology; Training Programs

DESCRIPTION (provided by applicant): This proposal seeks five more years of support to continue our newly established training program entitled Quantitative Biology and Physiology (QBP). Our mission is to train Ph.D. research scientists who have: (1) a quantitatively-based understanding of the principles underlying molecular biology, cell biology and physiology; (2) the capacity to synthesize modern methods with biology and physiology; (3) the capacity to synthesize mechanistic based modeling skills with biological and physical systems, and (4) the capacity to assess emergent behavior via integration across multiple levels (molecular-cellular-tissue-organ) of a system or process. The specific objectives of our renewal are: * To maintain an interdisciplinary faculty of mentors from Biomedical Engineering, Biology, Physics, Chemistry, Mathematics, Manufacturing Engineering, Electrical & Computer Engineering and Mechanical Engineering. * To provide a program curriculum that includes rigorous training in quantitative molecular biology, cell biology, and physiology inclusive of: Molecular and Genetic Systems, Cellular-to-Tissue Systems, Tissue-to-Organ/Sensory Systems, Scale-Independent Analysis and Modeling, and Multi-Scale Measurement Techniques. * To provide lab rotations that ensure exposure to quantitative and systems/dynamics research techniques relevant to problems at multiple scales of biology and physiology. * To provide graduate trainees with the opportunity to conduct thesis research that is interdisciplinary, quantitative, integrative, and necessarily linked to experimental data. * To establish a unique identity and impact of the QBP program via interactive components, including a Journal Club, Yearly QBP Symposium, Student-Faculty Science-Curriculum Retreats, and Monthly Dinners. Our first training grant cycle was successful. We are attracting high caliber trainees who have organized to create an empowering identity. These trainees address very challenging problems in areas ranging from biomaterials to neurobiology to genomic engineering and systems biology to integrated biomechanics, etc. These trainees also sustain activities that foster the themes of the QBP program so as to enrich the entire institution. We expanded our training mentor pool, improved the quality of the department as a whole, and matured our administrative approach based on experience and feedback. We look forward to the opportunity to continue this momentum during our next grant cycle.

描述（由申请人提供）：该提案寻求五年的支持，以继续我们新建立的培训计划，名为《定量生物学和生理学》（QBP）。我们的任务是培训博士学位。具有：（1）对分子生物学，细胞生物学和生理学基础原理的研究科学家：（1）基于定量的理解； （2）与生物学和生理学合成现代方法的能力； （3）与生物和物理系统合成基于机械的建模技能的能力，以及（4）通过跨系统或过程的多个级别（分子细胞组织 - 组织）整合来评估新兴行为的能力。我们更新的具体目标是： *维持生物医学工程，生物学，物理，化学，数学，制造工程，电气和计算机工程以及机械工程的导师跨学科教师。 *提供程序课程，包括包括：分子和遗传系统的定量分子生物学，细胞生物学和生理学的严格训练和多尺度测量技术。 *提供实验室旋转，以确保暴露于与生物学和生理学多个范围问题有关的定量和系统/动力学研究技术。 *为研究生学员提供了进行跨学科，定量，综合性且必要与实验数据相关的论文研究的机会。 *通过互动组件建立QBP计划的独特身份和影响，包括期刊俱乐部，年度QBP研讨会，学生教师科学科学课程务虚会和每月晚餐。 我们的第一个培训赠款周期取得了成功。我们正在吸引组织以创造授权身份的高素质受训者。这些受训者解决了从生物材料到神经生物学再到基因组工程和系统生物学再到综合生物力学等领域中非常具有挑战性的问题。这些受训者还维持促进QBP计划主题的活动，以丰富整个机构。我们扩大了培训导师池，提高了整个部门的质量，并根据经验和反馈来成熟我们的行政方法。我们期待在下一个赠款周期中继续这一势头的机会。