CANCER CONTROL RESEARCH PROGRAM

癌症控制研究计划

• 批准号: 7944592
• 负责人: JAMES D. SARGENT
• 金额: $ 7.55万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-21 至 2013-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7944592
• 关键词: Accounting; Adolescent; Adoption; Adverse effects; Alleles; Apolipoprotein E; Area; Behavior; Cancer Center Support Grant; Cancer Control; Cancer Control Research Program; Cancer Patient; Cancer Survivor; Collaborations; Communication; Communication Research; Communities; Complication; Continuity of Patient Care; Development; Diagnosis; Doctor of Philosophy; Early Diagnosis; Ensure; Exposure to; Fostering; Funding; Goals; Health Campaign; Health Services Research; Individual; Joints; Lead; Mammography; Manuscripts; Mentorship; Mission; Patients; Peer Review; Pharmaceutical Preparations; Policies; Prevention; Primary Health Care; Public Health; Publications; Publishing; Quality of Care; Quality of life; Research; Research Personnel; Resources; Risk Behaviors; Risk Reduction; Screening for cancer; Screening procedure; Smoke; Smoking; Structure; The Sun; Training Programs; Translating; Translations; Work; adolescent smoking; base; cancer care; cancer risk; cancer therapy; care systems; cognitive function; dissemination research; health care delivery; high risk; improved; mammography registry; meetings; member; mortality; movie; novel; programs; successful intervention

The mission of the Cancer Control Program is to promote collaborative research to reduce cancer risk and mortality and to enhance the quality of life of cancer patients. The Program fosters research across three thematic areas: (1) Prevention/risk reduction; (2) Screening/early detection; and (3) Quality of life/quality of care. Cross-cutting themes include research on communications, and translation/dissemination/adoption, with a developing health services research theme. The Program consists of 21 members from 10 departments accounting for $6.6 million in total funding, of which $4 million is from the NCI. This group of investigators has published 268 peer-reviewed manuscripts during the current funding period, of which 88 (33%) were joint publications with other programs, indicating a high degree of inter-programmatic collaboration, a substantial increase in such activity since the last review. In addition, 79 (29%) of the publications were intra-programmatic, reflecting collaborative work among our 21 program members. Program highlights include novel findings in all three thematic areas. Prevention researchers have published and disseminated findings from a trial to promote sun-safe behaviors among adolescents. They have published research showing a relation between exposure to smoking in movies and adolescent smoking, research that forms the basis for a public health campaign to reduce movie smoking depictions. Screening researchers lead one of 5 mammography registries in the U.S. and are disseminating successful interventions to promote cancer screening in primary care. Program members ask penetrating questions about the utility of current approaches to cancer screening, given issues such as over-diagnosis bias. Quality-of-life researchers have published novel findings on the adverse effects of cancer treatments on cognitive function, showing also that the epsilon 4 allele of APOE is associated with higher risk for this complication. Communications researchers are devising effective ways to discuss treatment and medication decisions with patients and working with the FDA to disseminate them. We are building our capacity to do research in communications and health services delivery through a recruitment and mentorship program. Program leaders host regular meetings among members and across programs to foster collaboration and ensure mentorship of young investigators, and members participate in a T32 Ph.D. training program in health services research. Going forward, the Program anticipates additional recruitment and continued expansion in areas of strength, including research into media influences on cancer risk behaviors, mammography research, and dissemination of practice systems of care to support cancer screening.

癌症控制计划的任务是促进协作研究，以降低癌症风险和 死亡率并提高癌症患者的生活质量。该计划促进了三个研究 主题领域：（1）预防/降低风险； （2）筛查/早期检测； （3）生活质量/质量 关心。跨切割主题包括有关通信的研究，翻译/传播/采用， 具有发展的卫生服务研究主题。该计划由10名成员组成 部门的总资金总额为660万美元，其中400万美元来自NCI。这组 调查人员在当前的资金期间发布了268份同行评审的手稿，其中88个 （33％）是与其他计划的联合出版物 自上次审查以来，协作，这种活动的大幅增长。此外，有79个（29％） 出版物是主要的，反映了我们21名计划成员的协作工作。 程序重点包括在所有三个主题领域的新发现。预防研究人员已发表 并从试验中传播了发现，以促进青少年的日晒行为。他们有 发表的研究表明，电影中吸烟与青少年吸烟之间的关系， 研究构成了减少电影吸烟描绘的公共卫生运动基础的研究。筛选 研究人员领导着美国5个乳房X线摄影注册机构之一，并正在传播成功 促进初级保健癌症筛查的干预措施。计划成员提出深入的问题 关于当前癌症筛查方法的实用性，诸如过度诊断偏见之类的问题。 生活质量的研究人员已经发表了有关癌症治疗对癌症治疗不利影响的新发现 认知功能，还表明epsilon 4 apoe等位基因与更高的风险有关 并发症。沟通研究人员正在设计有效的方法来讨论治疗和药物 与患者的决定并与FDA合作以将其传播。我们正在建立自己的能力 通过招聘和指导计划进行通信和卫生服务的研究。 计划负责人在成员和跨计划之间举办定期会议，以促进协作和 确保年轻调查员的指导，并参与T32博士学位。健康培训计划 服务研究。展望未来，该计划预计会有更多的招聘和继续扩展 力量领域，包括研究媒体对癌症风险行为的影响，乳房X线摄影 研究和传播实践系统以支持癌症筛查。