Disparities in CHD in the Jackson Heart Study

杰克逊心脏研究中冠心病的差异

基本信息

批准号：
7807995
负责人：
MARIO SIMS
金额：
$ 13.24万
依托单位：
UNIVERSITY OF MISSISSIPPI MED CTR
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-06-15 至 2013-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7807995
关键词：
Address African African American American Americas Area Atherosclerosis Award Cardiovascular Diseases Cardiovascular system Communities Consultations Coronary Coronary heart disease Data Development Plans Diabetes Mellitus Discrimination Disease Education Educational process of instructing Environment Epidemiologic Studies Epidemiology Ethnic group Exposure to Faculty Goals Health Health Personnel Health Policy Heart High Prevalence Hypertension Income Individual Knowledge Leadership Learning Life Link Measures Mediating Mediation Medical center Mentored Research Scientist Development Award Mentors Mentorship Minority Mississippi Modeling Neighborhoods Obesity Occupations Pathway interactions Patients Persons Policy Maker Prevalence Psychosocial Factor Research Research Design Research Ethics Research Personnel Risk Risk Factors Role Social Class Social support Socioeconomic Status Stress Testing Universities Writing career development design experience health disparity heart disease risk heuristics innovation mortality neighborhood association population based psychosocial racial discrimination skills statistics

项目摘要

DESCRIPTION (provided by applicant): This K01 award will allow the candidate, Dr. Mario Sims, to gain the skills, knowledge and experience required to become an independent investigator in health disparities research. Using data from the Jackson Heart Study (JHS), Dr. Sims will examine the extent to which neighborhood socioeconomic status (SES) and key psychosocial factors (discrimination, stress, and social support) impact coronary heart disease (CHD) in African Americans in Mississippi. The JHS is the largest epidemiologic, population-based study of cardiovascular disease (CVD) among African Americans, and one of its primary aims - to develop young talented minority investigators in the field of CVD research - will be accomplished through this KO1 award. CHD is the leading cause of CVD mortality in America, and Mississippi has the highest overall CVD mortality rate in the nation. Moreover, the cardiovascular health disparity between African Americans and whites is widening. Mississippi's CHD mortality rate is higher than the U.S. rate. African Americans have higher CHD prevalence and mortality rates than whites, and they also have a higher prevalence of risk factors associated with CHD such as hypertension, diabetes mellitus, and obesity which clearly might influence the higher prevalence of CHD mortality. To achieve his research and career development goals, Dr. Sims will follow a career development plan at the University of Mississippi Medical Center, designed to provide knowledge, skills, and experience in 6 core competencies required to be a successful independent investigator in health disparities research: 1) research excellence in the area of CHD disparities, 2) advanced statistics and study design, 3) research ethics, 4) leadership and management, 5) presentation and teaching, and 6) scientific writing. This will be accomplished through implementation of an individualized learning plan that includes: 1) academic coursework to develop cardiovascular disease disparity research skills; 2) mentorship and consultation with nationally and internationally recognized experts in cardiovascular disease epidemiology and health disparities research; 3) mentorship by faculty sensitive to the unique needs and issues facing minority academic faculty; and 4) innovative research using a multi-dimensional framework for examining how CHD prevalence among African Americans is influence by neighborhood environments, perceived discrimination, stress, and social support. The proposed mentored research has three specific aims: 1) to examine the extent to which neighborhood SES is associated with CHD among African Americans; 2) to determine the degree to which perceived racial discrimination, stress and social support are associated with CHD among African Americans; and 3) to analyze the extent to which the association of neighborhood SES and CHD is mediated by psychosocial factors among African Americans. This is the first study of its kind to examine multiple pathways by which neighborhood SES and key psychosocial factors impact CHD risk in African Americans in Mississippi, a state with the highest CHD rate in the nation. This research will enable health-care providers to adequately serve their patients with CHD knowing that where they live and their exposure to discrimination, stress, and a lack of social support are sequelae to CHD. This research will also show which factors health policy makers need to focus on in order to address and eliminate CHD disparities.

描述（由申请人提供）：该K01奖将使候选人Mario Sims博士能够获得成为健康差异研究独立研究者所需的技能，知识和经验。使用杰克逊心脏研究（JHS）的数据，SIMS博士将研究密西西比州非裔美国人的社区社会经济地位（SES）和关键的社会社会社会因素（歧视，压力和社会支持）影响冠心病（CHD）。 JHS是非洲裔美国人中最大的流行病学，基于人群的心血管疾病（CVD）研究，其主要目标之一 - 将在CVD研究领域发展年轻才华横溢的少数群体研究人员 - 将通过该KO1奖实现。 CHD是美国CVD死亡率的主要原因，密西西比州的总体CVD死亡率最高。此外，非裔美国人和白人之间的心血管健康差异正在扩大。密西西比州的冠心病死亡率高于美国率。与白人相比，非洲裔美国人的冠心病患病率和死亡率更高，并且与高血压，糖尿病和肥胖相关的危险因素的患病率也更高，这显然可能会影响CHD死亡率较高的较高流行率。为了实现他的研究和职业发展目标，SIMS博士将遵循密西西比大学医学中心的职业发展计划，旨在在6个核心能力中提供知识，技能和经验，以成为健康差异研究的成功独立研究者：1）CHD差异领域的研究卓越研究，2）高级统计和研究设计，3）研究伦理学，4）领导力和管理，5）介绍，5）6）和教学，5）6）。这将通过实施个性化学习计划来实现：1）发展心血管疾病差异研究技能的学术课程； 2）与国家和国际认可的心血管疾病流行病学和健康差异研究方面的指导和协商； 3）教师的指导对少数学术教师面临的独特需求和问题敏感； 4）使用多维框架进行创新研究，以研究非洲裔美国人的冠心病患病率如何受到邻里环境，感知的歧视，压力和社会支持的影响。拟议中的指导研究具有三个具体的目的：1）研究非洲裔美国人中SES与CHD有关的程度； 2）确定认为种族歧视的程度，压力和社会支持与非洲裔美国人的冠心病有关； 3）分析邻里SES和CHD的关联是由非裔美国人中的社会心理因素介导的。这是研究多种途径的第一项研究，该途径通过这些途径影响了密西西比州非洲裔美国人的邻里SES和关键的心理因素，这是美国冠心病率最高的州。这项研究将使医疗保健提供者能够为患者提供冠心病患者的居住地，并在歧视，压力和缺乏社会支持的情况下为患者提供服务。这项研究还将表明健康政策制定者需要重点关注哪些因素，以解决和消除CHD差异。

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Weight status and high blood pressure among low-income African American men.

低收入非裔美国男性的体重状况和高血压。

DOI：
10.1177/1557988310385447
发表时间：
2011
期刊：
American journal of men's health
影响因子：
0
作者：
Bruce,MarinoA;Beech,BettinaM;Edwards,ChristopherL;Sims,Mario;Scarinci,Isabel;Whitfield,KeithE;Gilbert,Keon;Crook,ErrolD
通讯作者：
Crook,ErrolD

One size fits all? Race, gender and body mass index among U.S. adults.

一种尺寸适合所有人？