Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistry

甲基营养菌：用于发现新型天然产物和生物化学的尚未开发的细菌

• 批准号: 10810046
• 负责人: Aaron Webster Puri
• 金额: $ 1万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10810046
• 关键词: Academia; Admission activity; Anabolism; Bacteria; Biochemistry; Biology; Chemicals; Doctor of Philosophy; Goals; Methylococcaceae; Natural Products; Research; Research Personnel; Structure; Training; Universities; Utah; Work; career; experience; graduate school; novel; parent grant; programs; summer program; undergraduate research experience; undergraduate student

Project Summary/Abstract Ms. Victoria Medvedeva is an undergraduate student at the University of Utah. She is currently earning her B.S. in Biochemistry (with Honors) and expects to graduate in December of 2023. Ms. Medvedeva’s short- term goal is to be admitted to a PhD graduate program in Chemical Biology, and her long-term goal is to have a career in academia performing research related to biomedicine. Ms. Medvedeva has been working as an undergraduate researcher in the Puri Lab at the University of Utah since August of 2021. Through this summer undergraduate research experience, Ms. Medvedeva will perform research in the Puri Lab related to determining the biosynthesis of the novel natural product tundrenone, which is made by a methane-oxidizing bacterium. This work is directly related to the subject of the parent grant (R35GM147018-01; Methylotrophs: underexplored bacteria for discovering novel natural products and biochemistry). Ms. Medvedeva will also participate in structured undergraduate summer programs on campus. Together, this experience will help her receive the additional technical, operational, and professional training she needs to achieve her short- and long-term goals.

项目概要/摘要 维多利亚·梅德韦杰娃女士是犹他大学的本科生，目前正在赚钱。 她获得了生物化学学士学位（荣誉学位），预计将于 2023 年 12 月毕业。 学期目标是考取化学生物学博士研究生课程，她的长期目标是拥有 梅德韦杰娃女士在学术界从事与生物医学相关的研究。 自 2021 年 8 月起在犹他大学 Puri 实验室担任本科研究员。今年夏天 本科生研究经验，Medvedeva 女士将在 Puri 实验室进行与确定相关的研究 新型天然产物 tundrenone 的生物合成，由甲烷氧化细菌制成。 工作与父资助的主题直接相关（R35GM147018-01；甲基营养菌：尚未开发） 发现新型天然产物和生物化学的细菌）梅德韦杰娃女士也将参加。 校园内结构化的本科暑期课程将帮助她获得学位。 她需要额外的技术、操作和专业培训来实现短期和长期目标。