CLINICAL NUTRITION RESEARCH UNIT

临床营养研究室

• 批准号: 7856109
• 负责人: ALAN CHAIT
• 金额: $ 29.9万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7856109
• 关键词: CLINICAL; NUTRITION; RESEARCH; UNIT

DESCRIPTION, OVERALL (provided by applicant): The major goal of the Clinical Nutrition Research Unit (CNRU) at the University of Washington is to promote and enhance interdisciplinary nutrition research by bringing together basic science and clinical investigators on a cooperative basis. Because of the multidisciplinary nature of nutrition, close interaction across disciplines and optimal use of resources is necessary to better understand the relationships among diet, health and disease states. By providing a number of Core facilities, the CNRU integrates and coordinates research activities in the field of nutrition and aims to foster new interdisciplinary research collaboration, stimulate new research activities, improve nutrition education at multiple levels and facilitate the nutritional management of patients. The four Cores are: 1) an Animal Studies Core, the Physiology Component of which measures body composition and energy expenditure in rodents, and a Genetic Component, which provides genetically defined mouse models for use in studies of nutrient-gene interactions; 2) an Analytic Core to provide Affiliate Investigators with cost-efficient state-of-the-art nutritional assays in both human subjects and experimental animals, and to help with new methods development; 3) a Human Studies Core to provide facilities and assistance for investigators with their clinical research, and 4) an Administrative and Enrichment Core that is responsible for the day-to-day administration of the CNRU. This Core also arranges a series of seminars, retreats, and Visiting Professorships, and administers the Pilot and Feasibility and New Investigator Programs. These programs are aimed at stimulating nutrition research by junior investigators and by more established investigators new to the field of nutrition in response to evolving research interests at the University of Washington. This Core also contains a biostatistical component that supports both basic and clinical research. Thus, the CNRU provides facilities and support for the large and varied nutrition research base of the University, which consists of 78 Affiliate Investigators. The major research foci of the University of Washington's CNRU are lipids and atherosclerosis, diabetes and body weight regulation, and obesity, i.e. chronic diseases of major importance to the health of the nation. The presence of the CNRU at the University of Washington stimulates not only research, but also educational and clinical activities in the area of nutrition.

描述，总体（由申请人提供）： 华盛顿大学临床营养研究部（CNRU）的主要目标是通过合作将基础科学和临床研究人员汇总在一起，以促进和增强跨学科的营养研究。由于营养的多学科性质，必须在学科之间进行密切相互作用和资源的最佳使用，以更好地了解饮食，健康和疾病状态之间的关系。通过提供许多核心设施，CNRU将营养领域的研究活动融合并协调研究活动，并旨在促进新的跨学科研究合作，刺激新的研究活动，在多个层面上改善营养教育，并促进患者的营养管理。 这四个核心是：1）动物研究核心，这是测量啮齿动物中人体组成和能量消耗的生理组成部分，以及一种遗传成分，该成分提供了遗传定义的小鼠模型，用于在营养基因相互作用的研究中使用； 2）一种分析核心，可在人类受试者和实验动物中为会员研究人员提供成本效益的最先进的营养测定，并帮助新方法开发； 3）人类研究核心，旨在为研究人员提供临床研究，以及4）行政和丰富核心，负责CNRU日常管理。该核心还安排了一系列的研讨会，务虚会和访问教授职位，并管理飞行员和可行性以及新的调查人员计划。这些计划旨在刺激初级调查人员和较成熟的营养领域的研究人员，以响应华盛顿大学不断发展的研究兴趣。该核心还包含一个支持基础研究和临床研究的生物统计组成部分。 因此，CNRU为大学的大型营养研究基础提供了设施和支持，该研究基础由78位会员研究人员组成。华盛顿大学CNRU的主要研究重点是脂质和动脉粥样硬化，糖尿病和体重调节以及肥胖症，即对国家健康至关重要的慢性疾病。华盛顿大学CNRU的存在不仅刺激了研究，还刺激了营养领域的教育和临床活动。