Comparative Functional Genomics INBRE in Maine

比较功能基因组学 INBRE 缅因州

• 批准号: 7899646
• 负责人: Patricia H. Hand
• 金额: $ 28.27万
• 依托单位: MOUNT DESERT ISLAND BIOLOGICAL LAB
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-23 至 2012-09-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7899646
• 关键词: Comparative; Functional; Genomics; INBRE; Maine

DESCRIPTION (provided by applicant): The proposed ME IDeA Network of Biomedical Research Excellence (ME-INBRE) in comparative functional genomics is led by the Mount Desert Island Biological Laboratory and is composed of two research institutions, one graduate degree granting institution, seven undergraduate institutions and one community college. ME-INBRE, with the expertise, strengths, and research resources of its research institutions, and the strong commitment of all its institutions to building research capacity in ME, is uniquely positioned to exploit the power of comparative functional genomics to discover important information about the genetic properties and function of genes of diverse species, and to use this topic as the scientific focus for institutional development, research training, and career development. ME-INBRE is having an unprecedented impact in our state by creating a new baseline of excellence in biomedical research and training, which already has enhanced the career development of investigators, substantially increased undergraduate student interest and accomplishments in science and health-related careers, and enhanced research infrastructure. Furthermore, we have created a stable and effective organizational structure capable of growing with ME-INBRE in the next grant period. The proposed INBRE builds on this structure to 1) increase the number of ME-INBRE undergraduate institutions from four to seven and include one college from ME's community college system established n 2003, 2) establish eight new investigator research projects, 3) expand support for graduate students from The University of ME's Graduate School of Biomedical Sciences established in 2006, 4) extend outreach to undergraduate students in northern ME, 5) create a new outreach program for high school students, and 6) significantly expand state, regional, and national collaborations. PUBLIC HEALTH RELEVANCE (provided by applicant): Research and training in comparative functional genomics will lead to a better understanding of mechanisms that control expression of genes that have significant roles in physiology, pharmacology, development, regeneration, and disease resistance and treatment. ME-INBRE will be a pipeline for students and faculty to pursue health research careers, and will enhance institutional development and scientific knowledge.

描述（由申请人提供）：拟议的比较功能基因组学 ME IDeA 生物医学研究卓越网络（ME-INBRE）由山漠岛生物实验室领导，由两个研究机构、一个研究生学位授予机构、七个本科生组成机构和一所社区学院。 ME-INBRE 凭借其研究机构的专业知识、优势和研究资源，以及其所有机构对建设 ME 研究能力的坚定承诺，在利用比较功能基因组学的力量来发现有关 ME 的重要信息方面具有独特的优势。不同物种基因的遗传特性和功能，并利用该主题作为机构发展、研究培训和职业发展的科学焦点。 ME-INBRE 通过在生物医学研究和培训方面建立了新的卓越基准，在我们州产生了前所未有的影响，这已经促进了研究人员的职业发展，大大提高了本科生对科学和健康相关职业的兴趣和成就，并且加强研究基础设施。此外，我们还创建了一个稳定有效的组织结构，能够在下一个资助期内与 ME-INBRE 一起成长。 拟议的 INBRE 在此结构的基础上 1) 增加 ME-INBRE 本科生的数量 机构从 4 个增至 7 个，其中包括 2003 年建立的 ME 社区学院系统中的一所学院，2) 建立 8 个新的研究者研究项目，3) 扩大对 2006 年建立的 ME 大学生物医学科学研究生院研究生的支持，4)将外展范围扩大到缅因州北部的本科生，5) 为高中生制定新的外展计划，6) 显着扩大州、地区和国家的合作。 公共卫生相关性（由申请人提供）：比较功能基因组学的研究和培训将有助于更好地理解控制基因表达的机制，这些基因在生理学、药理学、发育、再生以及抗病和治疗中发挥重要作用。 ME-INBRE 将成为学生和教师从事健康研究职业的渠道，并将加强机构发展和科学知识。