INBRE: MUSC: ENHANCEMENT OF BIOENGINEERING PROGRAM AT MUSC

INBRE：MUSC：加强 MUSC 的生物工程项目

• 批准号: 8168149
• 负责人: ROGER R MARKWALD
• 金额: $ 26.99万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-12 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168149
• 关键词: Adhesions; African American; Arts; Biology; Biomedical Engineering; Centers of Research Excellence; Collaborations; Commit; Communication; Computer Retrieval of Information on Scientific Projects Database; Development; Developmental Biology; Engraftment; Environment; Experimental Models; Faculty; Fostering; Funding; Genetic Engineering; Goals; Grant; Hand; Hispanics; Home environment; Institution; Joints; Mentors; Minority; Modeling; Pharmaceutical Preparations; Recruitment Activity; Regenerative Medicine; Research; Research Personnel; Resources; Scientist; Screening procedure; Source; South Carolina; Stem cells; Students; Tissues; Toxic Environmental Substances; Training; United States National Institutes of Health; Work; migration; programs; stem cell biology; Adhesions; African American; Arts; Biology; Biomedical Engineering; Centers of Research Excellence; Collaborations; Commit; Communication; Computer Retrieval of Information on Scientific Projects Database; Development; Developmental Biology; Engraftment; Environment; Experimental Models; Faculty; Fostering; Funding; Genetic Engineering; Goals; Grant; Hand; Hispanics; Home environment; Institution; Joints; Mentors; Minority; Modeling; Pharmaceutical Preparations; Recruitment Activity; Regenerative Medicine; Research; Research Personnel; Resources; Scientist; Screening procedure; Source; South Carolina; Stem cells; Students; Tissues; Toxic Environmental Substances; Training; United States National Institutes of Health; Work; migration; programs; stem cell biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. For over five years, the three research institutions (CRUs) in South Carolina have been working to promote the INBRE theme of regenerative medicine, bioengineering, and developmental biology. This effort is highlighted by joint programs in bioengineering between Clemson and MUSC, the establishment of endowed chairs in regenerative medicine at Clemson, MUSC and USC and joint COBRE grants. These efforts have resulted in better communications, interactions, and research environment within the BRIN/INBRE network. In this renewal, each CRU will manage an interactive Research/Technological Core Unit whose purposes will be to build and coordinate specialized research teams/partnerships with PUI faculty and students and to assist in recruiting new faculty. Specifically, at MUSC, we will provide a Stem Cell Core Unit whose goals/aims will be to provide not only extensive hands-on training but also, through monthly seminars, conceptual understanding of the types of stem cells, their basic biology, and how they can be used to study mechanisms of adhesion, migration, proliferation, or applied to tissue or genetic engineering or to screening environmental toxins or drugs. MUSC Core faculty and staff will assist and collaborate in PUI project development. Specific experimental models of variable complexity have been established by which PUI faculty can elect to become a part of a competitive research team or use the models to develop independent and interdependent research programs. One of these models is a state-of-the-art, single (stem) cell engraftment model that is available at only four or five institutions worldwide. A major objective of all collaborative projects and mentoring will be that the work can be done and sustained by PUI faculty at their home institutions. At MUSC, our recruitment efforts will be committed to successfully recruiting two minority scientists (African American and Hispanic) with goals being to increase our competitive funding strengths in stem cell biology and to assure long term continuation of collaborations fostered by the INBRE program.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 五年多来，南卡罗来纳州的三个研究机构（CRUS）一直在努力促进再生医学，生物工程和发展生物学的inbre主题。 克莱姆森（Clemson）和MUSC之间的生物工程联合计划强调了这一努力，在克莱姆森（Clemson），MUSC和USC和USC以及联合柯布雷（Cobre Cobre）赠款中建立了捐赠医学的捐赠椅子。 这些努力导致了BRIN/INBRE网络中更好的沟通，互动和研究环境。在此续约中，每个CRU将管理一个互动研究/技术核心单元，其目的是与PUI教师和学生建立和协调专业研究团队/合作伙伴关系，并协助招募新教师。具体而言，在MUSC，我们将提供一个干细胞核心单元，其目标/目标不仅是提供广泛的动手培训，还可以通过每月的研讨会提供对干细胞类型，基本生物学的概念理解，以及如何用于研究粘合，迁移，扩散，扩散，扩散，或应用于组织或遗传的环境或药物筛查或筛选耐药性或药物的效果或筛选性效果。 MUSC核心教职员工将协助和合作PUI项目开发。 已经建立了可变复杂性的特定实验模型，PUI教师可以选择成为竞争性研究团队的一部分，或者使用这些模型来制定独立和相互依存的研究计划。这些模型之一是一种最先进的单个（STEM）细胞植入模型，在全球仅四个或五个机构可用。 所有协作项目和指导的一个主要目标是，PUI教师可以在其家庭机构中完成和维持工作。 在MUSC，我们的招聘工作将致力于成功招募两名少数族裔科学家（非裔美国人和西班牙裔），目标是提高我们在干细胞生物学方面的竞争资金优势，并确保长期延续Inbre计划促进的合作。