NIH Director's Pioneer Award

NIH 院长先锋奖

基本信息

批准号：
7672469
负责人：
JUNYING YUAN
金额：
$ 82.76万
依托单位：
HARVARD MEDICAL SCHOOL
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-30 至 2012-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7672469
关键词：
14q12 Address Adult Affect Alleles Alzheimer&apos s Disease American Amino Acids Amyloid Fibrils Amyloid beta-Protein Animals Antithrombins Apoptosis Autophagocytosis Award BH3 Domain Back Behavior Binding Biochemistry Biological Assay Biological Models Biology Biomedical Research Birds Blast Cell Caenorhabditis elegans Calculi Cardiovascular system Caspase Caspase-1 Cell Culture Techniques Cell Death Cell physiology Cells Cellular biology Cessation of life Chemicals Chemistry China Chromosomes Cirrhosis Collaborations Complex Congo Red Cowpox virus Culture Media Cysteine Protease Death Domain Defect Dementia Development Developmental Biology Discipline of Nursing Disease Disulfide Linkage Doctor of Philosophy Dominant-Negative Mutation Due Process Dyes Education Embryonic Development Endoplasmic Reticulum Environment Enzymes Event Evolution Faculty Feeling Fellowship Fibroblasts Floor Foundations Friends Functional disorder Future General Hospitals Genes Genetic Genets Genome Hand Health Heart Homologous Gene Human Human Genome Huntington Disease Husband Ice Image Immune system In Vitro Inclusion Bodies Individual Induction of Apoptosis Institutes Institution Interleukin Activation Interleukin-11 Interleukin-3 Interleukins Intuition Ischemic Brain Injury Journals Knowledge Laboratories Labyrinth Lead Learning Left Length Libraries Link Liver Location Lysosomes Mammalian Cell Mammals Maps Massachusetts Mediating Medicine Mentors Methods Microinjections Mind Mining Mitochondria Modeling Molecular Molecular Chaperones Molecular Conformation Motor Mus Mutation Names Nature Necrosis Nematoda Nerve Degeneration Neuraxis Neurobiology Neurodegenerative Disorders Neurons Neurosciences Occupations Organ Organelles Paper Parkinson Disease Pathology Pathway interactions Patients Peer Review Peptide Hydrolases Phosphoric Monoester Hydrolases Phosphorylation Point Mutation Population Positioning Attribute Postdoctoral Fellow PrPSc Proteins Prevention Prion Diseases Prions Process Professional Education Property Protein C Inhibitor Protein Conformation Protein Dephosphorylation Protein Family Protein Synthesis Inhibition Proteins Proto-Oncogenes Publishing Recruitment Activity Regulation Research Research Personnel Research Support Resistance Rest Reverse Transcriptase Polymerase Chain Reaction Risk Role Science Sensorineural Hearing Loss Starvation Stress Stroke Structure Students Study Section Symptoms System Technology Testing Therapeutic Thinking Thrombosis Time Training Transfection Transgenic Mice Trust Trustees Uncertainty United States National Institutes of Health Universities University of Texas M D Anderson Cancer Center Up-Regulation Visit Walking Wild Type Mouse Withdrawal Work age related base biological adaptation to stress cDNA Library career caspase 12 caspase-2 caspase-8 cell suicide coping cytotoxicity deprivation developmental neurobiology dimer editorial endoplasmic reticulum stress factor C fascinate gain of function graduate student hearing impairment high throughput screening human Huntingtin protein human disease in vivo inhibitor/antagonist insight interest intermolecular interaction medical schools meetings multicatalytic endopeptidase complex mutant nervous system disorder neuron development neuron loss neuronal survival novel polyglutamine polymerization post-doctoral training pressure prevent prion hypothesis prion-like professor programs protein aggregation protein degradation protein expression protein folding protein function protein misfolding protein oligomer repaired research study response small molecule small molecule libraries success tissue/cell culture tool treatment strategy trend unpublished works

项目摘要

No Abstract provided

没有提供摘要

项目成果

期刊论文数量（2）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity.

DOI：
10.1016/j.immuni.2013.01.015
发表时间：
2013-05-23
期刊：
IMMUNITY
影响因子：
32.4
作者：
Py, Benedicte F.;Gonzalez, Santiago F.;Long, Kai;Kim, Mi-Sung;Kim, Young-A.;Zhu, Hong;Yao, Jianhua;Degauque, Nicolas;Villet, Regis;Ymele-Leki, Patrick;Gadjeva, Mihaela;Pier, Gerald B.;Carroll, Michael C.;Yuan, Junying
通讯作者：
Yuan, Junying