ARDS - EDEN Protocol

ARDS - EDEN 协议

• 批准号: 7824276
• 负责人: Roy G. Brower
• 金额: $ 50.35万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7824276
• 关键词: ARDS; EDEN; Protocol

¿ Objectives: 1. To assess the safety and efficacy of initial trophic enteral feeding followed by advancement to full-calorie enteral feeding vs. initial advancement to full-calorie enteral feeding management strategies in reducing mortality and morbidity in patients with ALI or ARDS ¿ Hypotheses: 1. Initial trophic feeding followed by full-calorie enteral feeding will improve clinical outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as compared to early, full-calorie enteral feeding.

目标： 1。评估初始营养肠内喂养的安全性和效率，然后进步到全卡路里肠内喂养与最初的进步与最初的进步，以降低ALI或ARDS患者的全卡路里肠内喂养管理策略，以降低死亡率和发病率 假设： 1。最初的营养喂养，然后是全卡路里肠内喂养将改善临床结果（特别增加了ALI或ARDS患者的60天的无通风天数，并降低了60天的医院死亡率），通过减少系统性注射和与早期的喂养并发症的数量相比，全身注射的次数减少了全身注射的数量。