Movable Equipment for DDB Animal Facility

DDB动物设施的移动设备

• 批准号: 7853794
• 负责人: Suzanne L Craig
• 金额: $ 49.64万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-10 至 2011-11-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7853794
• 关键词: Accreditation; Animal Welfare Act; Animals; Budgets; Caring; Decontamination; Disinfection; Environment; Equipment; Funding; Future; Health; House mice; Human Resources; IACUC; International; Laboratory Animals; Medical; Occupational Safety; Policies; Research; Research Support; Safety; South Carolina; Specific Pathogen Frees; System; Translational Research; United States National Institutes of Health; Universities; animal care; animal facility; drug discovery; germ free condition; human disease; mouse model; programs

DESCRIPTION (provided by applicant): The specific aims of this proposal are to: (1) Enhance centrally managed animal facilities at the Medical University of South Carolina to support the conduct of NIH- and other PHS-supported research; (2) Assist MUSC in maintaining the excellence of its AAALAC-accredited animal care and use program and outstanding record of compliance with the USDA Animal Welfare Act and DHHS policies related to care and use of laboratory animals; and (3) Provide needed housing for mice in a new facility utilizing ventilated racks to optimize the safety and comfort of the animals and protect the health of the research and animal care personnel. The budget requests funds for movable equipment (ventilated rack systems to house mouse models of human disease) to be installed in a new animal facility in the Drug Discovery Building at the Medical University of South Carolina (MUSC). The Drug Discovery Building (DDB) is a strategic expansion of MUSC's research capabilities in translational research. The Division of Laboratory Animal Studies (DLAR) manages the animal care and use program in a specific pathogen free (SPF) environment, with review and oversight from the Institutional Animal Care and Use Committee (IACUC) and continuous full accreditation from AAALAC-International since 1987. The equipment will facilitate ongoing compliance with all provisions and standards of the USDA, PHS, and AAALAC-International. Maintaining an SPF environment and remaining in compliance with current and future standards of laboratory animal care and use demand the highest achievable standards of disinfection, decontamination and occupational safety.

描述（由申请人提供）：本提案的具体目标是： (1) 加强南卡罗来纳医科大学集中管理的动物设施，以支持 NIH 和其他 PHS 支持的研究的开展； (2) 协助 MUSC 保持其 AAALAC 认证的动物护理和使用计划的卓越性，以及遵守美国农业部动物福利法和与实验动物护理和使用相关的 DHHS 政策的良好记录； (3) 在新设施中利用通风架为小鼠提供所需的住房，以优化动物的安全性和舒适度，并保护研究和动物护理人员的健康。该预算要求为南卡罗来纳医科大学 (MUSC) 药物发现大楼的新动物设施安装可移动设备（用于容纳人类疾病小鼠模型的通风架系统）提供资金。药物发现大楼 (DDB) 是 MUSC 转化研究能力的战略扩展。实验动物研究部 (DLAR) 在特定的无病原体 (SPF) 环境中管理动物护理和使用计划，并接受机构动物护理和使用委员会 (IACUC) 的审查和监督，并自 AAALAC-International 持续全面认证1987 年。该设备将有助于持续遵守 USDA、PHS 和 AAALAC-International 的所有规定和标准。维持 SPF 环境并保持符合当前和未来的实验动物护理和使用标准，需要可达到的最高消毒、去污和职业安全标准。