Housing Equipment to Meet Social Needs of Nonhuman Primates

满足非人类灵长类动物社会需求的住房设备

• 批准号: 7852989
• 负责人: CHARLOTTE HOTCHKISS
• 金额: $ 49.42万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7852989
• 关键词: Amendment; Animal Husbandry; Animal Model; Animal Welfare Act; Behavior; Biological Models; Biomedical Research; Equipment; Funding; Grooming; Guidelines; Health; Housing; Human; Laboratories; Phase; Prevention therapy; Primates; Protocols documentation; Public Health; Recommendation; Research; Research Infrastructure; Research Project Grants; Research Support; Resources; Socialization; United States National Institutes of Health; Visual; Washington; Well in self; Work; animal care; flexibility; improved; meetings; nonhuman primate; operation; research study; social

DESCRIPTION (provided by applicant): The Washington National Primate Research Center (WaNPRC) has an extensive commitment towards support of research in nonhuman primate model systems. As part of this commitment, the WaNPRC continues to acquire resources necessary to meet experimental objectives using the most relevant, healthiest, well-adapted animal model possible. Social contact is widely recognized as the most effective prevention and therapy for abnormal behavior in laboratory primates, but may need to be limited for certain experiments. Acquisition of modular enrichment caging will greatly improve the ability of the WaNPRC to meet standards for animal husbandry and enhance psychological well-being, in turn supporting biomedical research utilizing nonhuman primates. For subjects on restricted protocols, flexible socialization options will allow primates visual contact, limited physical contact through grooming bars, or full physical contact and socialization during certain study phases, as dictated by protocol requirements. This flexibility will allow for the maximum possible socialization throughout the course of the study, thereby promoting the primate's psychological well-being as mandated in the 1985 Amendment to the Animal Welfare Act. The proposed caging meets and exceeds current federal regulatory standards, guidelines and recommendations. Relevance: The addition of new caging with a variety of options for socialization will benefit a wide variety of biomedical research funded by NIH to improve the public health. The infrastructure to provide optimal animal care and the best possible animal model is essential for the operation of the Washington National Primate Research Center, and supports research projects across a broad portfolio, currently 72 different projects, which work toward important advances for human health.

描述（由申请人提供）：华盛顿国家灵长类动物研究中心 (WaNPRC) 广泛致力于支持非人类灵长类动物模型系统的研究。作为这一承诺的一部分，WaNPRC 继续获取必要的资源，以使用最相关、最健康、适应性最强的动物模型来实现实验目标。社会接触被广泛认为是实验室灵长类动物异常行为最有效的预防和治疗方法，但对于某些实验可能需要限制。获得模块化富集笼具将大大提高 WaNPRC 满足畜牧业标准和增强心理健康的能力，从而支持利用非人类灵长类动物进行生物医学研究。对于受限协议的受试者，灵活的社交选项将允许灵长类动物进行视觉接触、通过梳理杆进行有限的身体接触，或在某些研究阶段按照协议要求进行充分的身体接触和社交。这种灵活性将在整个研究过程中实现最大程度的社会化，从而按照 1985 年动物福利法修正案的规定，促进灵长类动物的心理健康。拟议的笼养符合并超过现行联邦监管标准、指南和建议。相关性：增加具有多种社交选择的新笼舍将有利于 NIH 资助的各种生物医学研究，以改善公众健康。提供最佳动物护理和最佳动物模型的基础设施对于华盛顿国家灵长类动物研究中心的运营至关重要，并支持广泛的研究项目，目前有 72 个不同的项目，这些项目致力于人类健康的重要进步。