Assessment of Achilles Tendon Injury in Adolescents

青少年跟腱损伤的评估

• 批准号: 10676623
• 负责人: Kayla Seymore
• 金额: $ 4.32万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-29 至 2025-03-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10676623
• 关键词: 18 year old; 3-Dimensional; Adolescence; Adolescent; Adult; Advocate; Ankle; Area; Articular Range of Motion; Biomechanics; Child; Childhood; Clinical; Computer Models; Cumulative Trauma Disorders; Delaware; Development; Diagnosis; Disease; Epiphysial cartilage; Etiology; Exhibits; Fellowship; Foundations; Goals; Growth; Health; Health Sciences; Heel; Height; Imaging Techniques; Impairment; Incidence; Injury; Lower Extremity; Morphology; Motion; Muscle; Musculoskeletal; Pain; Pathology; Patients; Physical activity; Population; Populations at Risk; Quality of life; Questionnaires; Rehabilitation therapy; Reporting; Research; Research Personnel; Retirement; Running; Scientist; Severities; Sports; Stress; Symptoms; Task Performances; Techniques; Tendinopathy; Tendon Injuries; Tendon structure; Testing; Training; Triceps Brachii Muscle; Universities; Walking; Work; achilles tendon; active lifestyle; aged; calcaneum; career; clinical care; clinical diagnosis; clinical diagnostics; elastography; functional adaptation; functional disability; improved; in vivo; innovation; loss of function; mechanical properties; muscle strength; musculoskeletal injury; novel; post-doctoral training; premature; pressure; reduce symptoms; research clinical testing; ultrasound; youth sports

PROJECT SUMMARY/ABSTRACT The incidence of Achilles tendon injury in youth sports has increased, yet Achilles tendon pathology in adolescents has been poorly investigated. While the overuse injury of Achilles tendinopathy is clinically diagnosed by pain with loading and loss of function in adults, the same symptoms in adolescents are instead considered a growth plate disorder called calcaneal apophysitis. Calcaneal apophysitis and Achilles tendinopathy may onset at different times during musculoskeletal growth in adolescents who consistently overload their tendons. However, the involvement of Achilles tendon pathology amongst adolescents with general heel pain is unknown. Further, the etiology of Achilles tendon injury has yet to be determined in the adolescent population. It is speculated that an overdevelopment of triceps surae muscle alters Achilles tendon structure (i.e., morphology and mechanical properties), resulting in heel pain during loading and loss of function. With no clear clinical diagnostic delineation between apophysitis and tendinopathy for patients under 18 years old with heel pain, overlooking Achilles tendon pathology may result from an assumed diagnosis of calcaneal apophysitis. Misdiagnosis and subsequent misaligned treatment of Achilles tendon injury in adolescents can reduce quality of life and may impede the development of a physically active lifestyle into adulthood. The growing incidence rates of lower limb tendinopathies in adolescence, and premature retirement from youth sports due to debilitating injury, stress the need for adequate understanding of Achilles tendon injury. Yet, Achilles tendon pathology research is disproportionately focused on the adult population, potentially leaving the pediatric population at risk of long-term health issues. The objective of this proposal is to investigate the effect of heel pain on adolescent Achilles tendon health and lower limb biomechanics. Specifically, this study will evaluate Achilles tendon symptoms and lower limb impairments (Aim 1), Achilles tendon structure and triceps surae muscle strength alterations (Aim 2), and Achilles tendon loading profiles (Aim 3) of adolescents with complaints of heel pain compared to healthy adolescents. This work will contribute valuable evidence for establishing the pathoetiology of adolescent heel pain, which is necessary to properly diagnosis and treat adolescents with heel pain so they can maintain physically active lifestyles into adulthood. The long-term goal of this fellowship applicant is to investigate mechanisms of musculoskeletal injury and improve clinical rehabilitation. The interdisciplinary training this applicant will receive from expert biomedical researchers and clinical collaborators at the University of Delaware during the proposed fellowship will make her a valuable investigator, with proficiencies in clinical testing, innovative imaging techniques, and novel computational modeling. Further, this proposal will facilitate the applicant’s postdoctoral training, laying the foundation for a career as an independent clinical scientist and strong advocate for diversity in health science fields.

项目概要/摘要 青少年运动中跟腱损伤的发生率有所增加，但跟腱病理 青少年对跟腱病过度使用损伤的研究很少。 成人的诊断是疼痛、负荷和功能丧失，但青少年却有相同的症状 被认为是一种生长板疾病，称为跟骨骨突炎和跟腱炎。 肌腱病可能在青少年肌肉骨骼生长过程中的不同时间发作，这些青少年始终坚持 然而，青少年跟腱病理学的参与。 此外，跟腱损伤的病因尚未确定。 据推测，小腿三头肌的过度发育会改变跟腱。 结构（即形态和机械性能），导致加载过程中脚跟疼痛和失去 对于以下患者，骨突炎和肌腱病之间没有明确的临床诊断界限。 18 岁患有脚跟疼痛，忽视跟腱病理可能是由于假设的诊断 跟腱损伤的误诊和后续治疗不当。 青少年可能会降低生活质量，并可能阻碍身体活跃的生活方式的发展 青春期下肢肌腱病的发病率不断上升，以及过早退休。 由于衰弱性损伤而退出青少年运动，强调需要充分了解跟腱 然而，跟腱病理学研究不成比例地关注成年人群。 使儿科人群面临长期健康问题的风险。 该提案的目的是调查足跟疼痛对青少年跟腱的影响 具体来说，这项研究将评估跟腱症状和 下肢损伤（目标 1）、跟腱结构和小腿三头肌力量改变（目标 2），以及与其他人相比，抱怨足跟疼痛的青少年的跟腱负荷分布（目标 3） 这项工作将为建立该病的病理学提供宝贵的证据。 青少年足跟痛，这是正确诊断和治疗青少年足跟痛所必需的，以便他们 能够在成年后保持积极的生活方式 该奖学金申请人的长期目标是 研究肌肉骨骼损伤的机制并改善临床康复。 该申请人将从生物医学专家研究人员和临床合作者那里接受培训 特拉华大学在拟议的奖学金期间将使她成为一名有价值的研究员，具有熟练的能力 此外，该提案还将在临床测试、创新成像技术和新颖的计算模型方面取得进展。 促进申请人的博士后培训，为独立临床职业奠定基础 科学家和健康领域科学多样性的大力倡导者。