Biomaterials Engineering and Testing core (BET)

生物材料工程与测试核心（BET）

基本信息

批准号：
10670179
负责人：
ROBERT A LATOUR
金额：
$ 34.76万
依托单位：
CLEMSON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10670179
关键词：
Address Awareness Behavior Biocompatible Materials Biological Biomedical Engineering Bioreactors Centers of Research Excellence Chemicals Collaborations Complement Core Facility Data Analyses Development Device Designs Devices Disease Drug Delivery Systems Educational workshop Effectiveness Engineering Extracellular Matrix Faculty Fee Schedules Funding Goals Graduate Education Grant Image In Vitro Instruction Journals Laboratories Materials Testing Mechanics Medical Mentors Methods Natural regeneration Outcome Performance Phase Physiological Pilot Projects Postdoctoral Fellow Property Public Health Publications Qualifying Regenerative Medicine Research Research Personnel Research Project Grants Research Support Schedule Scientist Series Services Signaling Molecule Students System Systems Development Testing Tissue Engineering Tissues Training Training Activity Translational Research United States National Institutes of Health Universities biofabrication biomechanical test design human disease improved in vivo in vivo evaluation laboratory development programs repaired replacement tissue response software systems success sustainable resource systems research undergraduate education undergraduate research experience voucher working group

项目摘要

The Phase III Biomaterials Engineering and Testing (BET) Core will support the synthesis and characterization of biomaterials and the design of biomaterial systems for research projects focused on the development of translational regenerative medicine applications for the treatment of human disease. The BET Core will provide both the facilities and staff necessary to provide this research support as well as training and mentoring for facilities users. The BET Core will build upon its track record of providing this type of support over the past 9 years under the Phase I & II COBRE grants and will substantial enhance its facilities for bioreactor system design, development, and biofabrication in order to support the extended in vivo research services to be offered by the Translational Research Imaging (TRI) Core. Over the past Phase I and II COBRE programs, the BET core has provided the facilities and support contributing to the publication of over 300 referred journal publications as well as the success of several of our junior investigators for attaining their own independent NIH R01 funding. Under the Phase III program, it is our objective to develop the BET Core into a sustainable resource to provide facilities for the continued support of translational regenerative medicine research well beyond the Phase III grant period.

第三阶段生物材料工程和测试（BET）核心将支持合成和表征生物材料的研究和生物材料系统的设计，重点是开发转化再生医学在治疗人类疾病中的应用。 BET 核心将提供提供研究支持以及培训和指导所需的设施和人员设施用户。 BET Core 将以其过去 9 年来提供此类支持的记录为基础在第一期和第二期 COBRE 资助下，将大幅增强其生物反应器系统设计设施，开发和生物制造，以支持扩展的体内研究服务转化研究成像 (TRI) 核心。在过去的第一阶段和第二阶段 COBRE 项目中，BET 核心已还为 300 多种引用期刊出版物的出版提供了便利和支持我们的几位初级研究人员成功获得了独立的 NIH R01 资助。在下面第三阶段计划，我们的目标是将 BET 核心开发为可持续资源，提供设施表彰在第三阶段资助期结束后继续支持转化再生医学研究。