FLOW CYTOMETRY RESOURCE

流式细胞术资源

• 批准号: 7623566
• 负责人: DAVID R. PARKS
• 金额: $ 5.51万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7623566
• 关键词: Bioinformatics; Biological Assay; Biological Markers; Cancer Center; Cell Separation; Cells; Clinical Trials; Communities; Complex; Consult; Data Quality; Data Set; Development; Ensure; Evaluation; Flow Cytometry; Flow Cytometry Shared Resource; Goals; Hour; Individual; Laboratories; Malignant Neoplasms; Mission; Patients; Policies; Productivity; Recommendation; Research; Research Personnel; Research Training; Resource Sharing; Resources; Services; Signal Transduction; Stem Cell Development; Stem cells; Stratification; Techniques; Training; anticancer research; base; data acquisition; data management; design; effectiveness research; instrumentation; leukemia; member; pre-clinical; research study; tool

The Flow Cytometry Shared Resource provides cell analysis and cell sorting services for cancer research in the Stanford community. The mission of the Flow Cytometry Shared Resource is to (1) promote cancer research and training for cell-based assays at the highest level of quality and rigor, (2) bring new developments in instrumentation, technique and analysis for preclinical use in the Stanford research community, and (3) support early clinical trial analysis in patient management. The Flow Cytometry Shared Resource enhances the productivity and effectiveness of research by promoting high-content data acquisition, assuring the highest data quality and consistency, carrying out efficient cell sorting, providing reliable data management, educating and training researchers and consulting in experiment design and evaluation. A large majority (88%) of current use in this Shared Resource is by Cancer Center members. In fiscal year 2005, the Flow Cytometry Shared Resource provided approximately 12,500 hours of cell analysis and cell sorting service to 490 individual researchers in the laboratories of 97 Stanford investigators. An oversight committee provides recommendations on Shared Resource policies and activities, ensuring that this Shared Resource is aligned with the Cancer Center's strategic goals. This Shared Resource has been at the cutting edge in the development of stem cell analysis and intracellular signaling analysis in leukemia and other cancers. It will greatly facilitate new understanding of stem cells in cancer, development of bioinformatics tools for analysis of complex flow cytometric datasets, patient cell analysis, and early development of biomarkers for patient stratification.

流式细胞仪共享资源为癌症研究提供细胞分析和细胞分选服务 在斯坦福社区。流式细胞仪共享资源的任务是（1）促进癌症 最高质量和严格水平的基于细胞的测定的研究和培训，（2）带来新的 斯坦福研究中临床前使用的仪器，技术和分析的发展 社区和（3）支持患者管理中的早期临床试验分析。流式细胞仪 共享资源通过促进高核数据提高了研究的生产率和有效性 获取，确保最高数据质量和一致性，进行有效的单元格分类， 在实验中提供可靠的数据管理，教育和培训研究人员和咨询 设计和评估。在此共享资源中，当前使用的绝大多数（88％）是癌症中心 成员。在2005财政年度，流式细胞仪共享资源约为12,500小时 在97斯坦福大学实验室中为490个个人研究人员提供的细胞分析和细胞分类服务 调查人员。监督委员会提供有关共享资源政策的建议和 活动，确保这种共享资源与癌症中心的战略目标保持一致。这 共享资源一直处于干细胞分析和细胞内的开发中的最前沿 白血病和其他癌症中的信号分析。它将极大地促进对干细胞的新理解 在癌症中，开发用于分析复杂流式细胞术数据集的生物信息学工具，患者 细胞分析和生物标志物的早期开发用于患者分层。