Development Core-003

开发核心-003

• 批准号: 10660386
• 负责人: MARIA PISU
• 金额: $ 33.89万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-15 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10660386
• 关键词: Address; Alabama; Area; Cancer Burden; Cancer Center; Cancer Control; Cancer Control Research; Cancer Survivor; Caring; Censuses; Collaborations; Communities; Data; Data Analyses; Development; Eligibility Determination; Ensure; Environment; Evaluation; Food Access; Funding; Goals; Health; Health Services Accessibility; Human Resources; Inequity; Institution; Institutional Review Boards; Intervention; Life; Literature; Malignant Neoplasms; Methodology; Mission; National Cancer Advisory Board; National Cancer Institute; Outcome; Peer Review; Phase; Pilot Projects; Postdoctoral Fellow; Poverty; Poverty Areas; Prevention; Process; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk Factors; Rural; Training; Transportation; Universities; University of Alabama at Birmingham Cancer Center; cancer health disparity; career; efficacious intervention; experience; falls; graduate student; improved; member; programs; social; social health determinants; survivorship; synergism; therapy development

DEVELOPMENTAL CORE ABSTRACT The Developmental Core (DC) supports the mission of the University of Alabama at Birmingham (UAB)'s Center for Cancer Control in Persistent Poverty Areas (C3P2) to reduce the burden of cancer and cancer disparities in Persistent Poverty (PP) areas by expanding research and research capacity through implementation and evaluation of multilevel interventions to improve cancer outcomes across the cancer control continuum from prevention to survivorship. The DC expands research in cancer control in (PP) areas of Alabama by developing a research program that builds on the overarching research framework and the proposed research projects. This goal will be achieved by identifying and developing pilot projects in synergy with the C3P2 Community Advisory board (CAB) and the National Cancer Institute (NCI)'s Persistent Poverty Initiative Network (PPIN). The DC will bring together C3P2 investigators, including trainees from the Career Enhancement Core (CEC) and CAB members in a process to identify, select, and prioritize the most relevant and feasible pilot projects. Participation in cross-PPIN centers' collaborative projects will also be considered in this process. With this plan, the DC ensures that pilot projects address the needs and context of PP census tracts and fall within the themes of C3P2 and within the larger goals of the PPIN. Potential pilot projects will build on the current projects that examine the impact of changes in the Living Environment and the adaptation of efficacious interventions to improve cancer outcomes in PP areas, and may investigate multi-level interventions to address needs such as low food access and lack of transportation, as well as specific needs to improve cancer survivors' health. The DC also support the C3P2 mission of expanding research capacity in PP areas by providing research experience opportunities to CEC trainees and other investigators not affiliated with the center, and requiring pilot projects have at least one early career investigator as PI or investigator. All projects will be peer-reviewed to ensure scientific rigor and integrity. The DC will have at least two active projects in each funded year. Lastly, the DC will support the development and implementation of the pilot projects by coordinating the use of resources from the Research and Methods Core (RMC) and the Administrative Core (AC), supporting investigators with IRB applications, training, identifying personnel as needed, and evaluating progress. Thus, the DC is well poised to successfully support the C3P2 and contribute to the goals of the PPIN.

发展核心摘要 发展核心 (DC) 支持阿拉巴马大学伯明翰分校 (UAB) 的使命 持续贫困地区癌症控制中心（C3P2）减轻癌症和癌症负担 通过扩大研究和研究能力，消除持续贫困（PP）领域的差距 实施和评估多层次干预措施，以改善整个癌症的癌症结果 从预防到生存的控制连续体。 DC 扩大 (PP) 领域癌症控制研究 阿拉巴马州通过开发一个基于总体研究框架和 拟议的研究项目。这一目标将通过确定和开发协同试点项目来实现 与 C3P2 社区咨询委员会 (CAB) 和国家癌症研究所 (NCI) 的持续贫困 倡议网络（PPIN）。 DC 将汇集 C3P2 调查员，包括来自职业部门的实习生 增强核心 (CEC) 和 CAB 成员在识别、选择和优先考虑最相关的过程中 以及可行的试点项目。还将考虑参与跨 PPIN 中心的合作项目 这个过程。通过该计划，DC 确保试点项目满足 PP 普查的需求和背景 并属于 C3P2 的主题和 PPIN 的更大目标。潜在的试点项目将 以当前研究生活环境变化和适应的影响的项目为基础 改善 PP 地区癌症结果的有效干预措施，并可能调查多层次 采取干预措施来解决粮食获取困难和缺乏交通等需求，以及满足以下需求： 改善癌症幸存者的健康。 DC 还支持 C3P2 扩大研究能力的使命 PP 领域，为 CEC 学员和其他非附属研究人员提供研究经验机会 与中心合作，并要求试点项目至少有一名早期职业调查员作为 PI 或调查员。全部 项目将接受同行评审，以确保科学严谨性和完整性。 DC 将至少有两个活动的 每年资助的项目。最后，DC将支持试点的制定和实施 通过协调研究和方法核心（RMC）和 行政核心 (AC)，支持调查人员进行 IRB 申请、培训、确定人员 需要，并评估进展情况。因此，DC 已准备好成功支持 C3P2 并做出贡献 实现 PPIN 的目标。