Behavioral Neuroscience Research Core

行为神经科学研究核心

基本信息

批准号：
10657730
负责人：
Charles Lee Pickens
金额：
$ 22.54万
依托单位：
KANSAS STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-15 至 2027-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10657730
关键词：
Advisory Committees Animal Experimentation Animal Husbandry Animal Model Animal Technicians Animals Area Award Behavioral Behavioral Assay Biochemical Biological Assay Chemistry Cognitive Collaborations Committee Members Communities Complement Core Facility Coupled Decision Making Dedications Doctor of Philosophy Electrophysiology (science)Elements Ensure Environment Equipment Extramural Activities Faculty Fluorescence Microscopy Funding Goals Grant Growth Health Human Individual Institution Kansas Laboratories Learning Letters Maintenance Mentors Microscopy Mission Modernization Neurobiology Neuronal Plasticity Neurosciences Neurosciences Research Phase Psychology Research Research Infrastructure Research Personnel Research Project Grants Resources Science Techniques Technology Training Universities Update animal care animal imaging cognitive ability cognitive neuroscience college designer receptors exclusively activated by designer drugs extracellular faculty research improved innovation laboratory facility member multidisciplinary neural circuit neuroinformatics optogenetics programs psychologic recruit success tenure track training opportunity

项目摘要

PROJECT SUMMARY: BEHAVIORAL NEUROSCIENCE CORE The Behavioral Neuroscience (BN) Core will support the overarching goals of the Cognitive and Neurobiological Approaches to Plasticity (CNAP) Center through the provision of resources, equipment, and technical support to enhance the research capabilities of CNAP primary projects and programs. The BN Core, housed within the Department of Psychological Sciences at Kansas State University, is the only dedicated BN core in Psychology in the state of Kansas. In Phase 2, the BN Core facility will be modernized and augmented through the addition of major equipment items to expand the capabilities of the facility and provide additional technical support. The BN Core will directly support two of the proposed Phase 2 primary projects (Diehl and Hall), the pilot grant and Scientific Exchange Network (SEN) programs, and the current community of users in the behavioral neuroscience program. The proposed modernization of the facility will promote the growth of behavioral neuroscience into exciting and innovative research areas that incorporate state-of-the-art techniques that will improve the research infrastructure for animal neuroscience research at K-State. Upgrades will allow the BN Core to introduce extracellular electrophysiological recordings coupled with optogenetics into research programs and will increase support for a range of biochemical assays, fluorescence microscopy, and Designer Receptors Exclusively Activated by Designer Drugs (DREADDs). The expansion of core facilities will also support CNAP programs by providing an excellent training environment for SEN partners. The Core Director and Core Technician will supply expertise in neuroscience and behavioral techniques to CNAP members with laboratories housed outside of the core facility. The comprehensive goal of the BN Core is to promote the ability of CNAP researchers to compete for extramural funding by incorporating technologies that are needed to answer the most challenging questions facing modern neuroscience researchers. The core is directed by Dr. Charles Pickens, a nationally known researcher in behavioral neuroscience in neural circuits of decision-making in animal models. Additional training and mentoring will be supplied by the CNAP mentoring team, External Advisory Committee members, and members from the BN collaborative network at K-State. A full-time Animal Care Technician will provide daily facility cleaning and maintenance and will meet the animal care and husbandry needs of facility users. Overall, the BN Core will support the attainment of the CNAP overarching aims by contributing to the success and growth of animal models of cognitive and neural plasticity, a central component of CNAP.

项目摘要：行为神经科学核心行为神经科学（BN）核心将支持认知和神经科学的总体目标可塑性神经生物学方法 (CNAP) 中心通过提供资源、设备和为增强CNAP重大项目和计划的研究能力提供技术支持。国阵核心，位于堪萨斯州立大学心理科学系，是唯一专门的 BN 堪萨斯州心理学核心。在第二阶段，BN 核心设施将进行现代化和增强通过增加主要设备项目来扩大设施的能力并提供额外的技术支援。 BN 核心将直接支持两个拟议的第二阶段主要项目（Diehl 和 Hall）、试点资助和科学交流网络（SEN）计划以及当前的用户社区行为神经科学计划。拟议的设施现代化将促进行为神经科学融入令人兴奋和创新的研究领域，融合了最先进的技术技术将改善堪萨斯州立大学动物神经科学研究的研究基础设施。升级将允许 BN Core 将细胞外电生理记录与光遗传学结合引入研究计划并将增加对一系列生化测定、荧光显微镜和由设计药物（DREADD）专门激活的设计受体。核心设施扩建还通过为SEN合作伙伴提供良好的培训环境来支持CNAP计划。核心总监和核心技术员将为 CNAP 提供神经科学和行为技术方面的专业知识成员的实验室位于核心设施之外。 BN 核心的综合目标是通过整合以下技术，提高 CNAP 研究人员竞争外部资金的能力需要回答现代神经科学研究人员面临的最具挑战性的问题。核心是由查尔斯·皮肯斯 (Charles Pickens) 博士指导，他是一位全国知名的神经回路行为神经科学研究员动物模型中的决策。 CNAP 指导将提供额外的培训和指导团队、外部咨询委员会成员以及堪萨斯州 BN 合作网络的成员。一个全职动物护理技术员将提供日常设施清洁和维护，并满足动物的需求设施使用者的护理和饲养需求。总体而言，BN 核心将支持 CNAP 的实现通过促进认知和神经可塑性动物模型的成功和发展来实现总体目标， CNAP 的核心组成部分。