Training Program in Metabolic Biology

代谢生物学培训计划

• 批准号: 10657469
• 负责人: Andreas Stahl
• 金额: $ 18.67万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10657469
• 关键词: Biology; Metabolic; Training Programs

Project Summary/Abstract The UC Berkeley/UCSF joint Training Program in Metabolic Biology (TPMB) offers unique opportunities for trainees to gain a strong foundation in rigorous, reproducible science, and to acquire the professional skills and knowledge to support future leaders in the field of human metabolic health and disease research. Built around an inter-departmental, trans-institutional training program, it brings together world-leading researchers and mentors from UCB's Department of Nutritional Sciences and Toxicology (NST) and UCSF's Diabetes Center (DC) to offer an unparalleled training experience for predoctoral fellows. TPMB seeks to attract a diverse group of highly qualified students from various academic backgrounds including biochemistry, cell and molecular biology, nutrition, and physiology. Our curriculum is build around development of scholarship and skills in research, teaching and professional service with the goals of establishing early research independence and laying a foundation for research integrity and responsibility. In addition to taking TPMB specific courses that emphasize human health and disease topics in metabolic regulation, research design and reproducibility, data analysis and interpretation, as well as ethical conduct, students will be able to rotate through laboratories both on the UCB and UCSF Parnassus campuses in their first year. TPMB students will experience a nurturing, diverse, and exciting environment that has build a well-established and integrated community of program leadership, researchers and preceptors across the two campuses and is well aware of the opportunities and potential challenges this approach offers. In order to make informed choices for their rotations incoming students will be exposed to the variety of metabolism centered research in the program through introductory lectures given by all TPMB faculty and participate in the programs joint annual retreat offering talks, posters, and social interactions with faculty, students, and postdocs. A central strength of TPMB is the quality of our faculty and the breath of human health and metabolism focused research topics ranging from central regulation of feeding behavior to adipocyte biology and ß-cells and state-of-the-art technical approaches from single-cell-sequencing, to metabolomics, genetics, stem cell biology, and bioengineering and the ability to pursue research in both clinical and preclinical settings. This wide range of expertise and approaches foster collaborative science and prepare TPMB students to successfully transition into independent careers in academia, industry, and government to tackle problems central to the mission of NIDDK and to improve human health and wellbeing.

项目概要/摘要 加州大学伯克利分校/加州大学旧金山分校代谢生物学联合培训计划 (TPMB) 为以下人员提供了独特的机会： 学员将在严谨、可重复的科学领域打下坚实的基础，并获得专业技能 建立了支持人类代谢健康和疾病研究领域未来领导者的知识。 围绕跨部门、跨机构的培训计划，它汇集了世界领先的研究人员 以及来自 UCB 营养科学和毒理学系 (NST) 以及 UCSF 糖尿病系的导师 中心 (DC) 旨在为博士前研究员提供无与伦比的培训体验。 来自不同学术背景的高素质学生群体，包括生物化学、细胞和 我们的课程围绕学术和生理学的发展而建立。 以建立早期研究为目标的研究、教学和专业服务技能 除了承担 TPMB 之外，还为研究的诚信和责任奠定了基础。 强调代谢调节、研究设计中人类健康和疾病主题的特定课程 和再现性、数据分析和解释以及道德行为，学生将能够轮换 TPMB 学生将在第一年通过 UCB 和 UCSF Parnassus 校区的实验室进行实验。 体验一个培育、多元化和令人兴奋的环境，该环境已经建立了完善的综合性 两个校区的项目领导、研究人员和导师组成的社区，并且非常了解 这种方法提供的机会和潜在挑战，以便为他们做出明智的选择。 轮换新生将接触到该项目中各种以新陈代谢为中心的研究 通过所有 TPMB 教员的介绍性讲座并参加项目联合年度务虚会 为教师、学生和博士后提供演讲、海报和社交互动是 TPMB 的核心优势。 是我们师资队伍的素质和人类健康与新陈代谢的重点研究课题范围广泛 从摄食行为的中央调节到脂肪细胞生物学和β细胞以及最先进的技术 从单细胞测序到代谢组学、遗传学、干细胞生物学和生物工程的方法 以及在临床和临床前环境中进行研究的能力和广泛的专业知识和能力。 方法促进协作科学并帮助 TPMB 学生成功过渡到 在学术界、工业界和政府中的独立职业生涯，解决与使命相关的核心问题 NIDDK 并致力于改善人类健康和福祉。