A Low-cost, Intravascular Ultrasound Transducer System for Measuring Blood Flow
用于测量血流的低成本血管内超声换能器系统
基本信息
- 批准号:7611201
- 负责人:
- 金额:$ 12.52万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-06-16 至 2010-12-31
- 项目状态:已结题
- 来源:
- 关键词:AngioplastyAnimalsBiocompatibleBloodBlood VesselsBlood flowCaliberCanis familiarisCaregiversCathetersClinicalDevicesElectrodesEnsureFeedbackFrequenciesGoalsImplantInterventionLeadLifeLightLiquid substanceManufacturer NameMeasurementMeasuresModelingMonitorOperative Surgical ProceduresPacemakersPaperPerformancePhasePhysiologicalProceduresResourcesStentsSurgeonSystemTechnologyTestingThrombectomyTransducersUltrasonic TransducerUltrasonographyUnited StatesUnited States National Institutes of HealthWorkblood flow measurementcostdesignflexibilityiliac arteryimprovedmeetingsminimally invasivepreventprogramspublic health relevanceretinal rodssuccesswound
项目摘要
DESCRIPTION (provided by applicant): Over a million minimally invasive procedures to preserve blood flow - angioplasties, stent placements, thrombectomies - are performed each year in the United States. The goal of this program is to provide means of measuring blood flow in these vessels during and after these procedures, something now not possible. We have developed a new blood-flow measuring component that can be integrated into minimally invasive interventional devices. During the procedure, it provides quantitative feedback to the operator on success in restoring blood flow; after the procedure, it can be remain as an indwelling lead to measure blood flow post-operatively. Its low power requirement also makes it suitable for long-term implantable use -- a small implanted unit, like a pacemaker, can monitor flow and wirelessly communicate an alert when declining blood flow demands intervention. This intravascular blood-flow measuring device is a newly developed, unique ultrasound transducer system. The design utilizes the principle of diffraction-grating transducers, which have been proven to measure blood flow accurately. A special configuration has been invented to make the transducer suitable for intravascular use: the electrodes on this transducer are wound around a rod, in helices, like a screw thread. This design has several advantages: it allows piezoplastics to be used at high frequencies, leading to low power requirements; use of piezoplastics makes a light, flexible device possible; it is easy to connect to; and, importantly, it is inexpensive to fabricate. Phase I of this project is to prove the concept by fabricating these transducers and demonstrating their capabilities in test phantoms, followed by placing one by minimally invasive means in a living animal and demonstrating successful blood flow measurement. PUBLIC HEALTH RELEVANCE: The goal of this program is to develop an intravascular device to measure blood flow during and after operations that improve or restore blood flow. By monitoring blood flow and alerting caregivers to a problem, it can prevent the serious consequences of too little flow of blood.
描述(由申请人提供):在美国,每年在美国进行超过一百万个最小的侵入性程序,以保存血流 - 血管成形术,支架位置,血栓切除术 - 在美国进行。该程序的目的是提供在这些过程中和之后的这些血管中测量血流的方法,这是现在不可能的。我们已经开发了一种新的血液测量成分,可以将其集成到微创的介入设备中。在过程中,它为恢复血流的成功提供了定量反馈。手术后,它可以作为留在术后测量血流的留置。它的低功率需求还使其适用于长期植入式使用 - 一个小型植入单元,例如起搏器,可以监视流量并无线传达警报,而在减少血流要求干预时。这种血管内血液测量装置是一种新开发的独特的超声传感器系统。该设计利用衍射胶化换能器的原理,这些原理已被证明可以准确测量血流。已经发明了一种特殊的配置,以使换能器适合于血管内使用:该传感器上的电极在杆周围缠绕在杆上,螺旋螺纹,例如螺纹。该设计具有多个优点:它允许在高频上使用压电塑料,从而导致低功率要求;使用压电塑料可以使轻便,灵活的设备成为可能;很容易连接;而且,重要的是,制造很便宜。该项目的第一阶段是通过制造这些换能器并证明其在测试幻像中的能力来证明这一概念,然后将一种用最小的侵入性手段放入活的动物中,并证明了成功的血液流量测量。公共卫生相关性:该计划的目的是开发一种在手术期间和之后测量血液流量以改善或恢复血液流动的方法。通过监测血流并提醒护理人员解决问题,它可以防止血液流量太少的严重后果。
项目成果
期刊论文数量(0)
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John Blebea其他文献
John Blebea的其他文献
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{{ truncateString('John Blebea', 18)}}的其他基金
Catheter-mounted Device for Measuring Intravascular Flow and Pressure
用于测量血管内流量和压力的导管安装装置
- 批准号:
8125373 - 财政年份:2009
- 资助金额:
$ 12.52万 - 项目类别:
Catheter-mounted Device for Measuring Intravascular Flow and Pressure
用于测量血管内流量和压力的导管安装装置
- 批准号:
8322642 - 财政年份:2009
- 资助金额:
$ 12.52万 - 项目类别:
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