VIMORTP (Vanderbilt Integrated Molecular Oncology Research Training Program)

VIMORTP（范德比尔特综合分子肿瘤学研究培训计划）

• 批准号: 10449242
• 负责人: WENDY KIMRYN RATHMELL
• 金额: $ 29.24万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10449242
• 关键词: Research Training; Training Programs; molecular oncology

PROJECT SUMMARY The pace of advances in molecular oncology discovery and integration to clinical practice is unparalleled. Modern cancer medicine has made the leap from model organism to studies in human-based systems, and the tools necessary to create large quantities of data, and to integrate and interpret them rapidly, have emerged simultaneously. In addition, the scientific leap has been accompanied by a dramatic increase in the importance of translational research and high quality clinical investigation. The result is an increased need for skilled workers who are able to be translate findings made at the bench, to have a broad understanding of working with human samples and data, who are capable communicators, and who have the skillset to be able to make informed connections to human disease. Our goal is to foster a cohort of highly trained, motivated, and effective clinician-investigators and translational scientists in this arena, who are poised to lead the coming advancements in the field of oncology research. Vanderbilt University and Vanderbilt University Medical Center (“Vanderbilt”) has a strong history of research in personalized or precision medicine, as well as significant depth in molecular oncology research. In addition, we have a longstanding and secure pipeline of MD-PhD and exceptional MD trainees joining our program, owing to the Harrison Society physician scientist training program in internal medicine, the pediatric physician-scientist pipeline, and the Holman Scholar Program in radiation oncology that have been a major successes of the Vanderbilt educational platform. We are proposing a training program that builds on that foundation, and selects 1-2 clinical fellow level trainees each year for an intensively mentored training experience. We propose the following aims: 1) to facilitate training in the fundamentals of discovery and implementation research in their selected area of expertise, 2) to provide structured mentoring in communication skills and team building for the future leadership needs in managing research teams, 3) to deliver focused training in protocol writing and manuscript preparation, and 4) to identify and develop trainees who are representative of the diversity of our population. Trainees will be provided an opportunity to expand skills where needed, in statistical methodology, informatics strategy, human tissue investigation, or tumor immunology. We have assembled a strong cohort of mentors representing translational cancer research, tumor immunology, drug development, and cancer epidemiology. Together, we are prepared to develop a new generation of clinician-investigators who are prepared to join and lead the exciting developments that promise to improve our ability to detect, manage, and cure cancer.

项目概要 分子肿瘤学发现和融入临床实践的进步速度是无与伦比的。 现代癌症医学已经从模式生物跨越到以人体为基础的系统研究，并且 创建大量数据并快速集成和解释这些数据所需的工具已经出现 此外，科学的飞跃也伴随着重要性的急剧增加。 转化研究和高质量临床研究的结果是对熟练技术人员的需求增加。 能够翻译在工作台上所做的调查结果的工人，对工作有广泛的了解 拥有人类样本和数据，他们是有能力的沟通者，并且拥有能够使 我们的目标是培养一批训练有素、积极主动且具有丰富知识的人。 该领域有效的临床研究人员和转化科学家，他们已准备好引领未来 范德比尔特大学和范德比尔特大学医学中心在肿瘤学研究领域取得了进展。 （“范德比尔特”）在个性化或精准医学方面拥有悠久的研究历史，以及重要的 此外，我们拥有长期且安全的医学博士和博士生渠道。 由于哈里森协会医师科学家培训计划，杰出的医学博士学员加入我们的计划 内科、儿科医师科学家管道以及放射领域的霍尔曼学者计划 肿瘤学是范德比尔特大学教育平台的重大成功。 在此基础上建立的培训计划，每年选择 1-2 名临床研究员级别的学员进行 我们提出以下目标：1）促进培训。 其所选专业领域的发现和研究实施的基础知识，2）提供 沟通技巧和团队建设方面的结构化指导，以满足未来管理领导力的需求 研究团队，3) 提供方案撰写和稿件准备方面的重点培训，以及 4) 确定 并培养代表我们人口多样性的学员。 有机会根据需要扩展统计方法、信息学策略、人体组织方面的技能 我们聚集了一批代表转化的强大导师。 癌症研究、肿瘤免疫学、药物开发和癌症流行病学，我们一起做好准备。 培养新一代临床医生-研究者，他们准备好加入并领导令人兴奋的 有望提高我们检测、管理和治愈癌症的能力的发展。