ADULT NEUROHORMONE MECHANISM RESPONSE TO LARVAL CROWDING

成虫神经激素机制对幼虫拥挤的反应

• 批准号: 2854171
• 负责人: JACK W DILLWITH
• 金额: $ 10.4万
• 依托单位: OKLAHOMA STATE UNIVERSITY STILLWATER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-30 至 2000-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2854171
• 关键词: Lepidoptera; environmental stressor; hormone regulation /control mechanism; invertebrate endocrinology; larva; lipid metabolism; lipid transport; mature animal; neurohormones

DESCRIPTION (Adapted from the applicant's abstract): Crowding has a detrimental impact on the behavioral, developmental, growth and reproductive processes of all animals especially vertebrates and insects. Even when all other environmental conditions are optimal, crowding, defined as high population density rearing, usually evokes a stress response in these processes. Since the operation of these precesses relies on underlying physiological and molecular mechanisms, crowding must be stimulating a stress response in these mechanisms. However, the physiological and molecular mechanisms through which crowding influences these processes are not well known. One approach to examining the impact of crowding on a neurohormonal mechanism is to examine each component of the mechanism separately. In this way, the response of the neuroendocrine gland can be separated from that of the target systems. This approach can be accomplished with the adipokinetic hormonal mechanism of Anticarsia gemmatalis because each component of the mechanisms is well characterized and this noctuid moth exhibits a strong behavioral and adipokinetic hormonal response to crowding. The applicants working hypothesis is that the enhanced lipid mobilizing capability of crowded insects is due to its influence on components of the adipokinetic hormonal mechanism associated with the level of the peptide hormone in hemolymph, the response/receptivity of the target systems to the hormone, or both.

描述（改编自申请人的摘要）：拥挤有一个 对行为、发育、生长和生殖产生有害影响 所有动物尤其是脊椎动物和昆虫的过程。 即使当所有 其他环境条件为最佳、拥挤、定义为高 人口密度饲养，通常会引起这些动物的应激反应 流程。 由于这些过程的运行依赖于底层 生理和分子机制，拥挤一定会刺激 这些机制中的应激反应。 然而，生理和 拥挤影响这些过程的分子机制是 不为人所知。 一种研究拥挤对环境影响的方法 神经激素机制是检查该机制的每个组成部分 分别地。 这样，神经内分泌腺的反应就可以是 与目标系统的系统分开。 这种方法可以 通过 Anticarsia 的脂肪运动激素机制完成 gemmatalis，因为机制的每个组成部分都有很好的特征 这种夜蛾表现出强烈的行为和脂肪运动激素 对拥挤的反应。 申请人的工作假设是 拥挤昆虫的脂质动员能力增强是由于 对相关脂肪运动激素机制成分的影响 随着血淋巴中肽激素的水平，反应/接受性 激素的目标系统，或两者。