Survey of the Health of Wisconsin

威斯康星州健康调查

• 批准号: 10626522
• 负责人: Kristen Mary Chossek Malecki
• 金额: $ 3.44万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-25 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10626522
• 关键词: Acceleration; Address; Advanced Malignant Neoplasm; African American; Basic Science; Behavioral; Biological; Biological Markers; Black race; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Control Research; Cancer Science; Catchment Area; Cause of Death; Censuses; Clinical; Clinical Sciences; Collaborations; Collection; Communities; Community Networks; Comprehensive Cancer Center; Consultations; Coupled; DNA; Data; Data Collection; Data Set; Development; Disparity; Economic Factors; Ensure; Environmental Pollution; Epidemiologist; Epidemiology; Ethnic Origin; Ethnic Population; Etiology; Faculty; Food Access; Fostering; Funding; Goals; Health Sciences; Health Surveys; Healthcare; Housing; Incidence; Individual; Infrastructure; Instruction; Investments; Knowledge; Link; Longitudinal cohort; Longitudinal cohort study; Malignant Neoplasms; Measurement; Methods; Mission; Monitor; NCI Center for Cancer Research; Neighborhoods; Nursing Faculty; Outcome; Physical Examination; Plasma; Population; Population Heterogeneity; Population Research; Population trends; Positioning Attribute; Prevalence; Protocols documentation; Questionnaires; Race; Recording of previous events; Reporting; Reproducibility; Research; Research Design; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Resources; Risk Factors; Rural; Rural Community; Sampling; Science; Scientist; Serum; Services; Shapes; Social Sciences; Strategic Planning; Surveys; System; Translational Research; Translations; Underrepresented Populations; United States; Universities; Urine; Validation; Vital Statistics; Wisconsin; anticancer research; biobank; biomarker discovery; burden of illness; cancer prevention; cancer risk; cancer therapy; community burden; community engagement; community organizations; cost effective; data sharing networks; design; disability; disparity reduction; epidemiology study; experience; geographic disparity; high risk; improved; innovation; interdisciplinary approach; member; multimodality; novel; novel strategies; population based; population health; programs; racial population; recruit; repository; research and development; research study; rural dwellers; sample collection; social; social factors; social health determinants; trend; wearable device

PROJECT SUMMARY / ABSTRACT Cancer remains a leading cause of death and disability in the United States and significant disparities across urban and rural, as well as racial and ethnic populations, exist. Population health sciences is an interdisciplinary approach drawing on basic, clinical, and social sciences to ensure translation and dissemination of new knowledge into useful applications across multiple sectors. The Survey of the Health of Wisconsin, SHOW, is a long-standing infrastructure for population health research. Established in 2008, SHOW includes an ongoing longitudinal cohort study of individuals representing the entire state of Wisconsin. As a University of Wisconsin Carbone Cancer Center (UWCCC) shared resource (SR), SHOW provides members with an existing data collection infrastructure and access to detailed survey data, physical exam measurements and biospecimens for advancing cancer control. UWCCC has a rich history of providing survey and research study design support for members through the Cancer Prevention and Outcomes Data (C-POD) SR; which was merged with SHOW to support cancer research across the entire UWCCC catchment area. In the current CCSG cycle, the C-POD and SHOW served 35 unique UWCCC members across all six scientific programs. SHOW includes detailed survey and physical exam data describing population trends in numerous well established and emerging cancer risk factors including multiple social determinants of health. These detailed data are coupled with stored biospecimens including urine, serum, plasma and DNA on over 4,000 individual Wisconsin residents. With this unique resource, SHOW’s goal is to facilitate innovative cancer research for improved cancer prevention and control across all communities in Wisconsin. This is accomplished through 3 aims: 1) Accelerate Cancer Surveillance and Cancer Prevention and Control Research through the Use of Existing Data. SHOW’s longitudinal data are available to UWCCC members to conduct etiologic research and monitor the prevalence of known and emerging cancer risk factors across the UWCCC catchment. 2) Facilitate the Development of New Population Based Cancer Research Utilizing SHOW Expertise and Infrastructure. Independent of the core SHOW data, SHOW can support new study design and survey development, including rigorous and reproducible methods and protocols for population based biospecimen collection and storage. 3) Foster Use of SHOW Biospecimens for Novel Cancer Research. SHOW maintains an extensive biorepository and expertise to support cost effective biomarker based cancer research. Dr. Malecki (CPC), the SHOW Faculty Leader and Dr. Schultz, the Facility Manager, have over twenty years of combined experience and expertise in population based epidemiologic, community engaged, and translational research. SHOW also maintains long-standing relationships with diverse African American and rural community based organizations serving those carrying the heaviest cancer burden. These ongoing partnerships are critical for UWCCC members to disseminate findings, to advance cancer control and reduce disparities in alignment with the UWCCC Strategic Plan.

项目摘要 /摘要 癌症缓解是美国的主要死亡和残疾原因 存在城市和族裔，以及种族和种族人口。 借助基本，临床和社会科学的方法，以确保新的翻译和分解 对多个部门的有用应用的知识。 长期存在于2008年建立的人口健康研究的基础设施。 个人的纵向研究代表了威斯康星州的整个状态。 Carbone Cancer Center（UWCCC）共享资源（SR），Show为会员提供了外界数据 收集基础架构以及访问详细的调查数据，体格检查的测量和生物测量 癌症控制。 通过癌症预防和结果数据（C-POD）SR的成员； 在当前的CCSG周期，C-POD和 Show在六个科学节目中为35个独特的UWCCC成员提供了详细的调查。 和体育考试数据数据描述了许多良好建立和新兴癌症风险的人口趋势 这些详细数据包括多个社会决定因素。 与此相关的生物测量包括尿液，血清，血浆和DNA超过4000个单独的Wissonsin居民 独特的资源，展示的目标是促进创新的癌症研究以改善癌症 在威斯康星州的所有社区中，这是通过3个目的进行的。 监视和癌症预防和控制研究数据。 UWCCC成员可以使用纵向数据，以进行etiologichrsearch并监视的流行率 UWCCCCCCCCCCCCAGE中已知和新兴的癌症风险因素。 基于POPTION的癌症研究表现出专业知识和基础设施。 显示数据，显示可以支持新的研究设计和调查开发，包括严格和可重复的 基于人群的生物测量收集和存储的方法和协议。 新型癌症搜索的生物测量。 基于生物标志物的成本效果癌症研究（CPC） 设施经理拥有超过20年的综合经验和基于人口的经验 流行病学，社区参与和翻译研究也保持了长期的态度。 与非洲裔美国和农村社区的多元化组织的关系，为携带的人提供服务 这些过度的伙伴关系对UWCCCCCCCCCCCCCCCCITAGE至关重​​要。 为了提高癌症控制并减少与UWCCCCCCCTEGIC计划一致性的差异。