Cincinnati Center for Clinical and Translational Sciences and Training

辛辛那提临床和转化科学与培训中心

基本信息

批准号：
9261619
负责人：
JAMES E. HEUBI
金额：
$ 341.94万
依托单位：
UNIVERSITY OF CINCINNATI
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-14 至 2019-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9261619
关键词：
Acute Adult Age Caring Child Clinical Clinical Informatics Clinical Research Clinical Sciences Clinical Trials Clinical effectiveness Collaborations Communities Development Discipline Education Educational process of instructing Elderly Environment Environmental Exposure Environmental Health Ethics Family Fostering Future Goals Government Officials Health Healthcare Informatics Information Technology Learning Longevity Master of Science Methods Multicenter Trials Participant Patients Performance Population Process Provider Race Recruitment Activity Research Research Methodology Research Personnel Science Scientist Services Site Training Translational Research Trust Underrepresented Minority Universities Vision Work base biomedical informatics career development data integration design health care delivery health disparity improved innovation medical specialties member named group next generation patient oriented research practice-based research network programs sex success

项目摘要

The vision of the Center for Clinical and Translational Science and Training (CCTST) at the University of Cincinnati is to be the Greater Cincinnati portal of entry for support of clinical and translational research with a goal to enfranchise stakeholders from a broad base to integrate research into healthcare delivery, improve community wellness, foster effective, efficient multisite trials, and train the clinical and translational research workforce of the future. We will realize this vision through three aims: (1) Empower stakeholders in the process of integrating research with healthcare practice and community wellness, (2) Create the workforce of the future, and (3) Optimize efficiency and effectiveness of clinical research. Building on the successes of the last 6 years, we propose innovative changes to existing programs and creation of new programs designed to provide support for high quality cutting-edge research done by teams of scientists. Building on our existing programs, we propose to (1) provide innovative programs in career development for a wide range of learners, (2) develop new pilot programs to support creation of solutions for obstacles to research, (3) expand our community engagement program to extend beyond Greater Cincinnati to stakeholders across the U.S., (4) provide more comprehensive support by biomedical informatics for the services provided by the CCTST, (5) expand support for patient-oriented research, and (6) help overcome regulatory and ethical challenges that impede clinical research in local and multisite studies. We propose innovative efforts directed toward fostering learning health networks and creating a Research Commons to provide more comprehensive support to investigators. We will focus on (1) teaching and implementing team science principles and encouraging collaboration across a variety of disciplines and stakeholders, (2) consolidation of clinical trials support across the academic health center by creating Cinci-HERO to help multicenter trials for which the CCTST affiliates are the leads (including serving as the IRB of record) or site participants and recruitment of populations across the lifespan including underrepresented minorities, those with environmental exposures and health disparities, and (3) acute care research and lifespan data integration that takes advantage of institutional strengths.

临床和转化科学与培训中心 (CCTST) 的愿景辛辛那提大学将成为大辛辛那提的入口门户，支持临床和转化研究的目标是让广泛的利益相关者能够整合研究医疗保健服务，改善社区健康，促进有效、高效多站点试验，并培训未来的临床和转化研究人员。我们将通过三个目标来实现这一愿景：（1）在整合过程中赋予利益相关者权力研究医疗保健实践和社区健康，(2) 创建劳动力未来，（3）优化临床研究的效率和效果。建立在过去 6 年的成功，我们对现有计划和创作提出创新性改变旨在为高质量前沿研究提供支持的新计划科学家团队。在我们现有计划的基础上，我们建议 (1) 提供创新为广泛的学习者提供职业发展计划，(2) 制定新的试点计划支持为研究障碍制定解决方案，(3) 扩大我们的社区参与计划将范围从大辛辛那提扩展到美国各地的利益相关者，(4) 提供更多生物医学信息学对CCTST提供的服务的全面支持，(5) 扩大对以患者为中心的研究的支持，以及（6）帮助克服监管和道德问题阻碍本地和多中心临床研究的挑战。我们提出创新的努力促进学习健康网络和创建研究共享为调查人员提供更全面的支持。我们将重点关注（1）教学和实施团队科学原则并鼓励跨各种领域的合作学科和利益相关者，(2) 整合整个学术界的临床试验支持健康中心通过创建 Cinci-HERO 来帮助 CCTST 附属机构进行的多中心试验是领导者（包括作为记录的 IRB）或现场参与者以及招募整个生命周期的人口，包括代表性不足的少数群体、环境暴露和健康差异，以及 (3) 急症护理研究和寿命数据发挥制度优势的一体化。