RHODE ISLAND CHILDREN'S EQUITY AND DEVELOPMENT STUDY (ENRICHED) - PHASES 1 AND 2

罗德岛州儿童公平与发展研究（丰富）- 第 1 和第 2 阶段

基本信息

批准号：
10923049
负责人：
Michael Silverstein
金额：
$ 127.65万
依托单位：
BROWN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10923049
关键词：
Adult African American Area Beginning of Life Biological Birth Black race Blood specimen Characteristics Child Child Development Child Health Child health equity Chronic Disease Clinical Collaborations Collection Consent Contracts Data Data Collection Data Coordinating Center Development Diagnostic Dietary Assessment Discrimination Disease Disparity Disparity population Economics Electronic Mail Enrollment Ensure Equity Ethnic Origin Ethnic Population Fathers First Pregnancy Trimester Generations Gestational Age Health behavior Home visitation Human Development Individual Instruction Intellectual functioning disability Intervention Interview Interviewer Investigation Knowledge Life Life Cycle Stages Life Expectancy Link Maternal Health Measures Mediating Mental Depression Mental Health Metabolic Minority Mission Monitor Mothers National Institute of Child Health and Human Development Neighborhoods Neurosecretory Systems Not Hispanic or Latino Outcome Parents Participant Patient Recruitments Patients Phase Phenotype Play Population Postpartum Period Poverty Pregnancy Pregnancy loss Pregnant Women Premature Birth Preventive Protocols documentation Psychopathology Race Reduce health disparities Reporting Research Rhode Island Role Sampling Schedule Second Pregnancy Trimester Self Administration Self Assessment Socioeconomic Status Specific qualifier value Strategic Planning Structure Testing Third Pregnancy Trimester Umbilical Cord Blood United States Update Urine Visit Woman design dietary economic disparity experience follow up assessment follow-up health disparity health outcome disparity high risk improved interest low socioeconomic status obstetric outcomes offspring outcome disparities participant retention phase 1 study population health postnatal prenatal prenatal health racial population recruit residence response retention rate sexual minority social social disparities sociodemographics socioeconomics transmission process

项目摘要

Completion of Assessments for Phase 1 and Recruitment and Assessments for Phase 2 The Division of Population Health Research (DiPHR) at the Eunice Kennedy Shriver National Institute of Child Health and Human Development conducts studies focusing on child health and human development. As part of DiPHR's mission, one area of interest is the investigation of the developmental origins of health disparities - i.e., differences in developmental outcomes between socially advantaged and disadvantaged groups. Here, we refer to unequal health outcomes between socioeconomic and race/ethnic groups, although disparities may also exist in the context of other socially disadvantaged statuses including intellectual disability and sexual minority status. Health disparities in the United States - in life expectancy and chronic disease - have their origins as early as the prenatal period. Early life conditions including poverty and discrimination generate disparities in health over the life course that become further entrenched in the population through their transmission across generations. Parental mental health problems, which are strongly linked with social and economic disadvantage as well as child development, may play a key mediating role in the transmission of disparities across generations. However, maternal and paternal psychopathology have not been fully considered as mechanisms contributing to disparities nor have been measured using phenotypically validated approaches (e.g. through structured diagnostic interviews). As a result, though disparities in health are well documented, the developmental mechanisms that impact disparities at the very beginning of life are not, particularly those which lead to developmental deficits that emerge long before disease states. The NICHD 2020 strategic plan highlights health disparities as a cross-cutting problem impacting the advancement of maternal health, birth outcomes, and child development; it emphasizes that “understanding the contribution of social, economic, structural, and regional factors is vital to advancing preventive, diagnostic, and intervention efforts” designed to mitigate health disparities. Advancing knowledge of the developmental mechanisms that generate disparities requires a more thorough understanding of how socioeconomic status and race/ethnicity influence the determinants of prenatal health and child development from gestation onward.

完成第1阶段的评估以及第2阶段的招聘和评估 Eunice Kennedy Shriver国家儿童健康与人类发展研究所的人口健康研究司（DIPHR）的重点是儿童健康和人类发展。作为DIPHR任务的一部分，感兴趣的领域是健康差异的发展起源的投资 - 即社会优势和弱势群体之间发展成果的差异。在这里，我们指的是社会经济和种族/族裔之间的不平等健康结果，尽管在其他受到社会困扰的地位（包括智力残疾和性少数群体状况）的背景下也可能存在差异。美国的健康差异 - 预期寿命和慢性病 - 早在产前时期就起源于其起源。早期的生活条件在内，包括贫困和歧视在整个生活过程中产生了健康的分布，这些分布通过世代相传的传播在人群中进一步根深蒂固。父母的心理健康问题与社会和经济灾难以及儿童发展密切相关，可能在世代相传的差异传播中起关键的中介作用。但是，尚未完全将母亲和父亲的心理病理学视为导致差异的机制，也没有使用表型验证的方法（例如，通过结构化诊断访谈）来衡量。结果，尽管健康差异有充分的记录，但影响生命开始时差异的发育机制并非如此，尤其是那些导致发育的人定义了早在疾病状态之前出现的。 NICHD 2020年战略计划重点介绍了健康分配，这是影响孕产妇健康，出生成果和儿童发展的跨切割问题；它强调，“了解社会，经济，结构和区域因素的贡献对于促进预防，诊断和干预工作至关重要”，旨在减轻健康分布。促进对产生分布的发展机制的了解需要更彻底地了解社会经济地位和种族/种族如何影响产前健康和儿童发展的决定者，从而开始妊娠。