Tufts Clinical and Translational Science Institute

塔夫茨临床与转化科学研究所

• 批准号: 9816143
• 负责人: Harry P. Selker
• 金额: $ 13.45万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-05 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9816143
• 关键词: Acculturation; Active Learning; Address; African American; Appalachian Region; Behavior; Biometry; Center for Translational Science Activities; Chinese American; Clinical; Clinical Research; Clinical Sciences; Communities; Data Analyses; Discipline; Discrimination; Environment; Evaluation; Goals; Institutes; Intervention; Latina; Latino; Location; Longevity; Mentors; Mentorship; Methods; Multi-Institutional Clinical Trial; Participant; Performance; Population Heterogeneity; Process; Puerto Rico; Research; Research Design; Research Personnel; Research Training; Resource Sharing; Resources; Risk Behaviors; Risk Factors; Role; Science; Screening for cancer; Services; Training; Training Support; Training and Education; Translational Research; Translations; Work; cancer prevention; cancer risk; career; community based participatory research; epidemiology study; ethnic diversity; health disparity; innovation; investigator training; novel; programs; racial and ethnic; racial diversity; skills

Project Abstract Maria Rodriguez Berrios ND is a promising early investigator with a focus on translational research addressing health disparities and community based participatory research. As a Latina investigator from Puerto Rico, she is committed to research that is broadly stakeholder engaged to eliminate health disparities. This diversity supplement will provide her the training and support through Tufts CTSI to reach her training goals. The training goals of the proposed investigator are well aligned with the overall aims and the community engagement and the research resources aims of Tufts CTSI: Overall AIM 1: Create an environment, resources, and services to stimulate and support the full spectrum of clinical and translational research (CTR) by leveraging the diverse expertise and assets of Tufts CTSI partners. Overall AIM 2: Cultivate broadly-engaged team science, actively including stakeholders, to promote relevant and impactful translation for diverse populations and across the lifespan. Overall AIM 3: Develop, demonstrate, and disseminate innovations in methods, research process improvement, and evaluation, to advance CTR locally and nationally. Overall AIM 4: Advance methods and performance of multi-site clinical trials, within the Tufts CTSI Clinical Research Network (CRN), the NCATS Trial Innovation Network, and in other multi-institutional networks. Overall AIM 5: Provide outstanding education, training, and mentoring, tailored to different roles and disciplines, to advance a diverse CTR workforce, and share these resources nationally. The candidate will utilize the resources of Tufts CTSI beginning with the training available through the Clinical and Translational Sciences graduate program. Using the skills she gains in the graduate program, she will conduct a data analysis to understand the impact of multiple risk factors, including novel risk factors of acculturation and discrimination on cancer screening and cancer prevention behaviors. This work, including community participants from African American, Chinese American, Latino, and Appalachian communities, will provide a broad perspective on the impact of location and racial/ethnic diversity and these novel risk factors on cancer prevention behaviors, and will provide targets for potential novel interventions to address cancer risk behaviors. Dr. Rodriguez Berrios will benefit from the resources of Tufts CTSI to achieve her research training aims, and prepare her for an independent research career. She will engage with the Stakeholder and Community Engagement Resource, the Clinical Translational Research Center, and the Biostatistics, Epidemiology and Research Design resources for experiential learning, and couple this with the formal training in the Clinical Translational Science Graduate Program and the mentorship of the Tufts CTSI PI and KL2 PI in order to develop the skills in broadly engaged team science.

项目摘要 Maria Rodriguez Berrios ND 是一位有前途的早期研究者，专注于转化研究 健康差异和基于社区的参与性研究。作为一名来自波多黎各的拉丁裔调查员，她 致力于广泛利益相关者参与的研究，以消除健康差距。这种多样性 补充品将通过塔夫茨 CTSI 为她提供培训和支持，以实现她的培训目标。 拟议研究者的培训目标与总体目标和社区非常一致 塔夫茨 CTSI 的参与和研究资源目标： 总体目标 1：创造环境、资源和服务来刺激和支持全方位的 利用塔夫茨 CTSI 合作伙伴的多样化专业知识和资产进行临床和转化研究 (CTR)。 总体目标 2：培养广泛参与的团队科学，积极让利益相关者参与其中，以促进相关 以及对不同人群和整个生命周期有影响力的翻译。 总体目标 3：开发、展示和传播方法、研究过程的创新 改进和评估，以提高本地和全国的点击率。 总体目标 4：塔夫茨 CTSI 临床中心内先进的多中心临床试验方法和性能 研究网络 (CRN)、NCATS 试验创新网络以及其他多机构网络。 总体目标 5：提供针对不同角色和需求的卓越教育、培训和指导 学科，以促进多元化的 CTR 员工队伍，并在全国范围内共享这些资源。 候选人将利用塔夫茨 CTSI 的资源，从通过临床提供的培训开始 和转化科学研究生项目。利用她在研究生课程中获得的技能，她将 进行数据分析以了解多种风险因素的影响，包括新的风险因素 癌症筛查和癌症预防行为的文化适应和歧视。这项工作包括 来自非裔美国人、华裔美国人、拉丁裔和阿巴拉契亚社区的社区参与者将 提供了关于地点和种族/民族多样性的影响以及这些新的风险因素的广阔视角 癌症预防行为，并将为解决癌症风险的潜在新干预措施提供目标 行为。 Rodriguez Berrios 博士将受益于塔夫茨 CTSI 的资源来完成她的研究培训 目标，并为她的独立研究生涯做好准备。她将与利益相关者接触并 社区参与资源、临床转化研究中心和生物统计学， 流行病学和研究 设计体验式学习资源，并将其与正式培训结合起来 临床转化科学研究生项目的博士，以及塔夫茨大学 CTSI PI 和 KL2 PI 的指导 为了发展广泛参与的团队科学的技能。