Multidisciplinary K12 Urologic Research (KURe) Career Development Program

多学科 K12 泌尿学研究 (KURe) 职业发展计划

• 批准号: 9325500
• 负责人: Dolores Jean Lamb
• 金额: --
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9325500
• 关键词: Alpha Cell; Area; Basic Science; Biology; Cell Cycle Regulation; Cellular biology; Childhood; Defect; Development; Doctor of Medicine; Doctor of Philosophy; Ensure; Environment; Faculty; Funding; Genetic; Genitourinary system; Genomics; Goals; Medicine; Mentors; Minority; Pathology; Peer Review; Physicians; Program Development; Recruitment Activity; Reproductive Health; Reproductive Medicine; Research; Research Personnel; Research Training; SECTM1 gene; Scientist; Stem cells; Structure; Teacher Professional Development; Training; Translational Research; United States National Institutes of Health; Urology; Woman; Work; career development; clinical translation; college; experience; gene therapy; lower urinary tract symptoms; male; male health; member; men; multidisciplinary; programs; reproductive tract; steroid hormone; steroid hormone receptor; strength training; urologic

DESCRIPTION (provided by applicant): This application seeks support for our competing renewal application for the Multidisciplinary K12 Urologic Research (KURe) Career Development Program to the Scott Department of Urology and the Center for Reproductive Medicine at Baylor College of Medicine. The research emphasis of this program is in the areas pediatric urology/genitourinary development, steroid hormone action, stem cells genetics and lower urinary tract symptoms (LUTS). The training faculty includes 7 Ph.D/M.D., Ph.D. faculty and11 M.D.s. Dr. Lamb will serve as both the Program Director and the Administrative Director of the KURe career development program. Dr. Boone will serve as co-Director. Drs. Lipshultz, Cunningham, Gonzales, Khera, Roth, Janzen will ensure the M.D. trainees are optimally trained in the urologic subspecialty areas of men's health and pediatric urology. The major research areas in the program include: genetics and genomics of genitourinary developmental defects, cell biology, steroid hormone receptors, male reproductive tract biology, genetics, cell cycle control, stem cells, gene therapy and LUTS. The trainees will be M.D. and Ph.D. junior faculty members at Baylor College of Medicine. Our program attracts highly qualified trainees who seek intensive and substantial research training in urology research with an emphasis on clinical translation. We have a defined recruitment plan that emphasizes the recruitment of women and minorities. The strengths of the training environment include highly respected, well-funded, experienced faculty, the high ranking national ranking for NIH funding of a Urology/Cell Biology/Genetics/Pathology departments, a structured mentoring program with required coursework, a cell biology graduate program with relevant course work and depth in both cell biology and genetics. Most importantly, we have a strong track record of training successful physician scientists. Our long- term goal is to train these young investigators to successfully compete for peer-reviewed funding and eventually to increase basic and translational research efforts in men's reproductive health research.

描述（由申请人提供）：本申请旨在为我们向贝勒医学院斯科特泌尿科和生殖医学中心提出的多学科 K12 泌尿学研究 (KURe) 职业发展计划的竞争性更新申请寻求支持。该项目的研究重点是儿科泌尿学/泌尿生殖发育、类固醇激素作用、干细胞遗传学和下尿路症状 (LUTS) 等领域。培养师资队伍包括博士/医学博士、博士7人。教师和 11 名医学博士Lamb 博士将担任 KURe 职业发展项目的项目总监和行政总监。布恩博士将担任联合主任。博士。 Lipshultz、Cunningham、Gonzales、Khera、Roth、Janzen 将确保医学博士学员在男性健康和儿科泌尿科泌尿科亚专业领域接受最佳培训。该项目的主要研究领域包括：泌尿生殖发育缺陷的遗传学和基因组学、细胞生物学、类固醇激素受体、男性生殖道生物学、遗传学、细胞周期控制、干细胞、基因治疗和LUTS。受训者将是医学博士和博士。贝勒医学院的初级教员。我们的项目吸引了高素质的学员，他们寻求泌尿学研究方面的强化和实质性研究培训，重点是临床转化。我们有明确的招聘计划，强调招聘女性和少数族裔。培训环境的优势包括备受尊敬、资金充足、经验丰富的教师队伍、泌尿学/细胞生物学/遗传学/病理学部门的 NIH 资助排名高的国家排名、包含所需课程的结构化指导计划、细胞生物学研究生课程具有细胞生物学和遗传学方面的相关课程作业和深度。最重要的是，我们在培训成功的医师科学家方面拥有良好的记录。我们的长期目标是培训这些年轻的研究人员成功竞争同行评审的资金，并最终增加男性生殖健康研究的基础和转化研究工作。

项目成果

Words of wisdom. Re: Fertility preservation in adolescent males: experience over 22 years at Rouen University Hospital.

至理名言。

• 发表时间: 2010-01
• 影响因子: 23.4
• 作者: Hwang, Kathleen;Lamb, Dolores J
• 通讯作者: Lamb, Dolores J

New advances on the expansion and storage of human spermatogonial stem cells.

人类精原干细胞扩增和储存的新进展。

• 发表时间: 2010-11
• 影响因子: 2.5
• 作者: Hwang, Kathleen;Lamb, Dolores J
• 通讯作者: Lamb, Dolores J

The fate of transitional urology patients referred to a tertiary transitional care center.

过渡泌尿科患者的命运被转诊至三级过渡护理中心。

• 发表时间: 2014-12
• 影响因子: 2.1
• 作者: Chan, Robert;Scovell, Jason;Jeng, Zachary;Rajanahally, Saneal;Boone, Timothy;Khavari, Rose
• 通讯作者: Khavari, Rose

Evaluating Outcomes of Differential Surgical Management of Nonfunctioning Upper Pole Renal Moieties in Duplex Collecting Systems.

评估双收集系统中无功能上极肾部分差异化手术治疗的结果。

• 发表时间: 2019
• 影响因子: 2.1
• 作者: Sheth, Kunj R;White, Jeffrey T;Janzen, Nicolette;Koh, Chester J;Austin, Paul F;Roth, David R;Tu, Duong D;Mittal, Angela;Wang, Ming;Gonzales, Edmond T;Jorgez, Carolina;Seth, Abhishek
• 通讯作者: Seth, Abhishek

Vesicoamniotic Shunting Improves Outcomes in a Subset of Prune Belly Syndrome Patients at a Single Tertiary Center.

膀胱羊膜分流术改善了单一三级中心部分梅干腹综合征患者的预后。

• 发表时间: 2018
• 作者: White, Jeffrey T;Sheth, Kunj R;Bilgutay, Aylin N;Roth, David R;Austin, Paul F;Gonzales Jr, Edmond T;Janzen, Nicolette K;Tu, Duong D;Mittal, Angela G;Koh, Chester J;Ryan, Sheila L;Jorgez, Carolina;Seth, Abhishek
• 通讯作者: Seth, Abhishek