Admin-Core-001

管理核心-001

基本信息

批准号：
10942944
负责人：
Jeffrey Nicholas Myers
金额：
$ 25.48万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2027-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10942944
关键词：
Administrative Coordination Administrator Advisory Committees Affect Agreement Basic Science Bioinformatics Biological Specimen Banks Cisplatin Clinical Research Collaborations Communication Communities Consult Consultations Data Coordinating Center Decision Making Dedications Discipline Drug resistance Employment Ensure Equilibrium Event Future Goals Grant Head and Neck Cancer Human Resources Institution Leadership Modeling Monitor Outcome Performance Periodicals Pharmacotherapy Preparation Publications Qualifying Quality Control Recommendation Regulation Reporting Research Research Activity Research Infrastructure Research Personnel Resistance Resources Rest Schedule Structure System Training Translational Research Work cost effective data integrity data management data quality design experience interdisciplinary approach lectures meetings multidisciplinary pre-clinical pre-clinical research quality assurance success symposium tumor

项目摘要

Administrative Core (Core A) SUMMARY The Administrative Core, led by Dr. Jeffrey Myers and Dr. Vlad Sandulache, and supported by the Center Administrator Dr. Toyin Babarinde, is an indispensable component of the Houston Center for Acquired Resistance Research (H-CARR). The overall objective of the Administrative Core (Core A) is to provide critical centralized support to the H-CARR and ensure seamless interactions and integration between the three projects and cores within the center as well as the broader ARTNet community. Core A is designed to monitor research activity and provide stable and continuous leadership that guides future scientific directions for this Research Center. Core A will leverage the wide-ranging scientific, research related experience of the Center Advisory Group in critical decision-making steps. The Administrative Core will ensure an emphasis on basic mechanistic and translational research and facilitate interdisciplinary and inter-project integration, including assistance in the establishment of collaborations with other ARTNet centers as well as the U24 ARTNet Coordinating Data and Management Center (ARTNet CDMC U24) and NCI staff. Core A will also have overall responsibility for fiscal and budgetary management of the H-CARR, including the employment of key personnel to ensure a highly qualified, well trained, managed, and diverse work force that will enable cost-effective and efficient use of resources. This Core will also monitor scientific integrity and overall compliance with all institutional, state, federal, and NCI regulations and requirements, as well as quality assurance for data integrity. The strength of Core A rest in its well-developed structure of intra-programmatic, intra-institutional, and external advisors who are all dedicated to support Core A Leaders through ongoing review, advice, and periodic meetings and recommendations to ensure robust scientific performance and progress toward the agreed upon programmatic goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open communications among all H-CARR investigators, provide a centralized resource for regulatory monitoring and compliance activities, and perform scheduled reviews of project and core activities and progress towards their goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open communications among all H-CARR investigators, engage in regulatory monitoring to optimize the successful outcome of the basic mechanistic and preclinical/translational research in resistance to drug therapy in head and neck cancer.

由杰弗里·迈尔斯（Jeffrey Myers）博士和弗拉德·桑杜拉奇（Vlad Sandulache）博士领导的行政核心（核心A）总结行政核心，并得到了中心管理员Toyin Babarinde博士的支持，是休斯顿获得抵抗力研究中心（H-Carr）的必不可少的组成部分。行政核心（核心A）的总体目标是为H-Carr提供关键的集中支持，并确保中心内三个项目和核心之间以及更广泛的ARTNET社区之间的无缝互动和集成。核心A旨在监测研究活动并提供稳定而连续的领导，从而指导该研究中心的未来科学方向。核心A将在关键决策步骤中利用中心咨询小组的广泛科学，研究与研究相关的经验。行政核心将确保强调基本的机械和转化研究，并促进跨学科和跨项目的整合，包括协助与其他ARTNET中心建立合作，以及U24 ARTNET协调数据和管理中心（ARTNET CDMC U24）和NCI员工。核心A还将对H-CARR的财政和预算管理负责，包括雇用关键人员来确保高素质，训练有素，管理，管理和多样化的劳动力，这将使资源具有成本效益有效的利用。该核心还将监控科学完整性和整体遵守所有机构，州，联邦和NCI法规和要求，以及数据完整性的质量保证。核心的力量在其良好发达的主要内部，机构内和外部顾问的结构中休息，他们全都致力于通过正在进行的审查，建议，定期会议和建议来支持核心领导者，以确保稳健的科学绩效和进步，以实现协议的计划目标。在核心A领导者的指导下，核心A还将为研究提供支持和基础架构，促进所有H-Carr研究人员之间的清晰和公开通信，为监管监控和合规活动提供集中资源，并对项目和核心活动进行预定的审查，并向其目标进行进步。在核心A领导者的指导下，核心A还将为研究提供支持和基础设施，促进所有H-CARR研究人员之间的清晰和开放通信，从事监管监测，以优化基本机械和临床前/转化研究的成功结果，以抵抗头和颈部癌症药物治疗。