Administrative Core

行政核心

• 批准号: 10707158
• 负责人: Jeffrey Nicholas Myers
• 金额: $ 24.95万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707158
• 关键词: Administrative Coordination; Administrator; Advisory Committees; Affect; Agreement; Basic Science; Bioinformatics; Biological Specimen Banks; Cisplatin; Clinical Research; Collaborations; Communication; Communities; Consult; Consultations; Data Coordinating Center; Decision Making; Dedications; Discipline; Drug resistance; Employment; Ensure; Equilibrium; Event; Future; Goals; Grant; Head and Neck Cancer; Human Resources; Institution; Leadership; Modeling; Monitor; Outcome; Performance; Periodicals; Pharmacotherapy; Preparation; Publications; Qualifying; Quality Control; Recommendation; Regulation; Reporting; Research; Research Activity; Research Infrastructure; Research Personnel; Resistance; Resources; Rest; Schedule; Structure; System; Training; Translational Research; Work; cost effective; data integrity; data management; data quality; design; experience; interdisciplinary approach; lectures; meetings; multidisciplinary; pre-clinical; pre-clinical research; quality assurance; success; symposium; tumor

Administrative Core (Core A) SUMMARY The Administrative Core, led by Dr. Jeffrey Myers and Dr. Vlad Sandulache, and supported by the Center Administrator Dr. Toyin Babarinde, is an indispensable component of the Houston Center for Acquired Resistance Research (H-CARR). The overall objective of the Administrative Core (Core A) is to provide critical centralized support to the H-CARR and ensure seamless interactions and integration between the three projects and cores within the center as well as the broader ARTNet community. Core A is designed to monitor research activity and provide stable and continuous leadership that guides future scientific directions for this Research Center. Core A will leverage the wide-ranging scientific, research related experience of the Center Advisory Group in critical decision-making steps. The Administrative Core will ensure an emphasis on basic mechanistic and translational research and facilitate interdisciplinary and inter-project integration, including assistance in the establishment of collaborations with other ARTNet centers as well as the U24 ARTNet Coordinating Data and Management Center (ARTNet CDMC U24) and NCI staff. Core A will also have overall responsibility for fiscal and budgetary management of the H-CARR, including the employment of key personnel to ensure a highly qualified, well trained, managed, and diverse work force that will enable cost-effective and efficient use of resources. This Core will also monitor scientific integrity and overall compliance with all institutional, state, federal, and NCI regulations and requirements, as well as quality assurance for data integrity. The strength of Core A rest in its well-developed structure of intra-programmatic, intra-institutional, and external advisors who are all dedicated to support Core A Leaders through ongoing review, advice, and periodic meetings and recommendations to ensure robust scientific performance and progress toward the agreed upon programmatic goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open communications among all H-CARR investigators, provide a centralized resource for regulatory monitoring and compliance activities, and perform scheduled reviews of project and core activities and progress towards their goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open communications among all H-CARR investigators, engage in regulatory monitoring to optimize the successful outcome of the basic mechanistic and preclinical/translational research in resistance to drug therapy in head and neck cancer.

行政核心（核心A）摘要 由Jeffrey Myers博士和Vlad Sandulache博士领导的行政核心，并在中心支持 管理员Toyin Babarinde博士是休斯顿获得抵抗中心的必不可少的组成部分 研究（H-Carr）。行政核心（核心A）的总体目标是提供关键的集中式 支持H-Carr，并确保三个项目和核心之间的无缝互动和集成 在中心以及更广泛的Artnet社区内。核心A旨在监视研究活动和 提供稳定而连续的领导，指导该研究中心的未来科学方向。核 A将利用Critical中心咨询小组的广泛科学，研究与研究的经验 决策步骤。行政核心将确保强调基本机械和翻译 研究并促进跨学科和项目间整合，包括在建立 与其他Artnet中心以及U24 ARTNET协调数据和管理中心的合作 （ARTNET CDMC U24）和NCI员工。核心A还将对财政和预算负责 H-Carr的管理，包括雇用关键人员，以确保高素质，很好 经过培训，管理和多样化的劳动力，将实现资源具有成本效益有效的利用。这 核心还将监控科学完整性和对所有机构，州，联邦和NCI的整体遵守 法规和要求以及数据完整性的质量保证。核心的力量在其上休息 专门的截然内部，机构内部和外部顾问的结构都致力于 通过正在进行的审查，建议和定期会议和建议来支持核心A领导者 强大的科学表现和朝着协议的程序化目标方向发展。在指导下 领导者的核心A核心A还将为研究提供支持和基础设施，促进清晰和开放 所有H-Carr调查人员之间的通信，为监管监控提供了集中资源和 合规活动，并对项目和核心活动进行预定的评论，并朝着他们的 目标。在核心A领导者的指导下，核心A还将为研究提供支持和基础架构， 促进所有H-Carr调查人员之间的清晰公开通信，进行监管 优化基本机理和临床前/转化研究的成功结果 头颈癌的药物治疗。