Core 3: Biostatistics, Data Management, and Bioinformatics

核心 3：生物统计学、数据管理和生物信息学

基本信息

批准号：
10931066
负责人：
Xuelin Huang
金额：
$ 16.14万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10931066
关键词：
Address Basic Science Bioinformatics Biometry Cancer Center Clinical Clinical Research Clinical Trials Collaborations Collection Communication Conduct Clinical Trials Confidentiality of Patient Information Consultations Data Data Analyses Data Collection Data Management Resources Data Security Databases Development Doctor of Medicine Ensure Experimental Designs Formulation Futility Genomics Human Resources Laboratory Study Lateral Methodology Monitor Multi-Institutional Clinical Trial Patients Process Proteomics Publications Publishing Quality Control Reporting Research Research Design Research Personnel Resources Safety Statistical Data Interpretation Statistical Models Techniques Texas Translational Research Universities Writing career cost effective data acquisition data integration data management data quality data resource design exome sequencing experimental study genome sequencing genomic data high dimensionality high throughput analysis innovation laboratory experiment leukemia meetings preclinical study programs prospective research study simulation sound symposium transcriptome sequencing whole genome

项目摘要

Project Summary The major objective of the Biostatistics and Bioinformatics Core (Core 3) is to provide centralized biostatistics, bioinformatics, and database support for all Projects and Cores. Core 3 will provide guidance in the design and conduct of clinical trials and other experiments that arise from the ongoing research of the SPORE, facilitate prospective collection, entry, quality control, and integration of data for the basic science, pre-clinical, and clinical studies, and provide bioinformatics data analysis of high-throughput and high-dimensional genomics data. We will provide innovative and tailored statistical modeling, simulation techniques, and data analyses for the main projects, developmental research and career enhancement projects, and other cores to achieve their specific aims. We will conduct data analyses and prepare statistical reports for all experiments within all projects, ensure that the results of all projects are appropriately interpreted, and assist all project investigators in the publication of scientific results. Core 3 will also be a resource for intra- and inter-SPORE collaborations, including study design and developing databases for multi-center clinical trials.

项目摘要生物统计学和生物信息学核心的主要目标（核心3）是提供集中的生物统计学，生物信息学和数据库支持所有项目和核心。核心3将在设计中提供指导进行临床试验和其他由孢子进行的研究引起的其他实验，促进前瞻性收集，进入，质量控制和基础科学数据的数据集成，临床前和临床研究，并提供高通量和高维基因组学的生物信息学数据分析数据。我们将提供创新和量身定制的统计建模，仿真技术和数据分析主要项目，发展研究和职业增强项目以及其他核心具体目标。我们将进行数据分析并准备所有实验的统计报告项目，确保对所有项目的结果进行适当的解释，并协助所有项目调查人员在出版科学结果中。核心3也将成为内部和跨间协作的资源，包括研究设计和开发用于多中心临床试验的数据库。