Michigan Center on Lifestage Environmental Exposures and Disease

密歇根生命阶段环境暴露和疾病中心

基本信息

批准号：
9465459
负责人：
Rita K Loch-Caruso
金额：
$ 67.19万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-04-15 至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9465459
关键词：
Address Administrator Advisory Committees Budgets Collaborations Communication Communities Community Outreach Consultations Core Facility Data Disease Educational workshop Elements Endocrine Ensure Environmental Exposure Environmental Hazards Environmental Health Environmental Impact Evaluation Event Faculty Feedback Focus Groups Fostering Funding Opportunities Genetic Goals Grant Individual Inflammation Internet Knowledge Leadership Life Medical Mentors Metabolic Michigan Mission National Institute of Environmental Health Sciences Oxidative Stress Performance Periodicity Pilot Projects Program Development Program Evaluation Publications Records Reporting Research Research Infrastructure Research Personnel Research Training Retreatment Science Scientist Structure Technology Translations Vision Visit Work career career development efficacy evaluation epigenetic regulation human disease improved innovation meetings member programs public health intervention response service programs skills symposium theories tool

项目摘要

SUMMARY/ABSTRACT (Administrative Core) The Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) mission has two overarching goals: to accelerate research that defines and explains impacts of environmental exposures during vulnerable stages of life, and to promote translation of these findings to improve medical and public health interventions for the mitigation of human disease. We implement our mission through integrated research, training and community engagement overseen by the Administrative Core. The Administrative Core is led by the center director with assistance from the deputy director. This core is the administrative unit for the Pilot Project Program (led by the deputy director), Career Development Program (led by an Associate Director), and Research Engagement Program (led by an Associate Director). Three Research Teams (Inflammation & Oxidative Stress Team; Endocrine & Metabolic Disruption; and Genetics & Epigenetics Regulation) are elements of the Research Engagement Program with research team leaders included as members of the Administrative Core. The research teams are key mechanisms for members to explore new collaborations and for coordinating responses to funding opportunities. Inclusion of leadership of the Pilot Project Program, Career Development Program, and Research Engagement Program in the Administrative Core addresses the center objective that these programs operate in an integrative manner. Administrative Core Faculty will be assisted by an administrative assistant and web designer/administrator. The core works as collaborative team to provide an effective and efficient administrative infrastructure to achieve the mission of M-LEEaD. The core is responsible for organizing M-LEEaD activities such as meetings, retreats, consultant visits, symposia, seminars, and focus groups, and maintaining records of reports, minutes, and evaluation results from such events. In addition, the core provides fiduciary oversight of the budgets. The core obtains and considers input on emerging theories, paradigms, technologies, and discoveries in environmental health sciences and biomedicine at multiple levels, from research team reports to director meetings to Internal Advisory Committee meetings and including the External Advisory Board. The Administrative Core has responsibility for the Career Development Program and the Pilot Project Program, ensuring that these programs encourage innovative research for all members, but especially for early-stage investigators. The core ensures inclusion of input on opportunities for community engagement and fosters multi-directional dialogue among M-LEEaD scientists, community members, and regulatory stakeholders. The core coordinates responses to urgent environmental hazards and concerns, including interactions with other NIEHS Environmental Health Sciences Core Centers, the NIEHS, and other relevant organizations. Finally, the core is responsible for evaluation of the efficacy of the center programs, cores, and activities, taking corrective action as warranted.

摘要/摘要（行政核心）密歇根生命阶段环境暴露和疾病中心 (M-LEEaD) 任务有两个总体目标：加速研究，定义和解释期间环境暴露的影响生命的脆弱阶段，并促进这些发现的转化，以改善医疗和公共卫生减轻人类疾病的干预措施。我们通过综合研究来履行我们的使命，由行政核心监督的培训和社区参与。行政核心由以下人员领导中心主任在副主任的协助下。该核心是试点的管理单元项目计划（由副主任领导），职业发展计划（由副主任领导），以及研究参与计划（由副主任领导）。三个研究团队（炎症和氧化应激团队；内分泌和代谢紊乱；和遗传学与表观遗传学调控）是研究参与计划的要素，其中研究团队领导者包括作为成员行政核心。研究团队是成员探索新合作和协调对融资机会的反应。纳入试点项目计划、职业的领导力行政核心的发展计划和研究参与计划解决了该中心的问题目标是这些计划以综合方式运作。行政核心教师将得到协助行政助理和网页设计师/管理员。核心工作作为协作团队提供一个有效且高效的行政基础设施，以实现 M-LEEaD 的使命。核心是负责组织 M-LEEaD 活动，例如会议、务虚会、顾问访问、研讨会、研讨会和焦点小组，并保存此类报告、会议记录和评估结果的记录事件。此外，核心还提供预算的信托监督。核心获取并考虑输入关于环境健康科学和领域的新兴理论、范式、技术和发现多个层面的生物医学，从研究团队报告到董事会议再到内部咨询委员会会议，包括外部顾问委员会。行政核心负责职业生涯发展计划和试点项目计划，确保这些计划鼓励创新面向所有成员的研究，尤其是早期研究人员。核心确保包含输入社区参与的机会并促进 M-LEEaD 科学家之间的多向对话，社区成员和监管利益相关者。核心协调对紧急环境的响应危害和担忧，包括与其他 NIEHS 环境健康科学核心中心的互动， NIEHS 和其他相关组织。最后，核心负责评估效果中心计划、核心和活动，并根据需要采取纠正措施。