Tri-I Stimulating Access to Research in Residency program (Tri-I StARR - NIAID)

Tri-I 促进住院医师研究项目 (Tri-I StARR - NIAID)

• 批准号: 10592130
• 负责人: ETHEL CESARMAN
• 金额: $ 44.89万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-15 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10592130
• 关键词: Address; Applications Grants; Area; Biology; Biomedical Research; Board Certification; COVID-19 pandemic; Career Choice; Cities; Clinical; Clinical Pathways; Clinical Research; Communicable Diseases; Complex; Country; Development; Development Plans; Diagnosis; Disease; Disparity; Doctor of Philosophy; Educational Curriculum; Educational process of instructing; Eligibility Determination; Environment; Etiology; Evaluation; Faculty; Fellowship; Fracture; Funding; Funding Opportunities; Future; Generations; Goals; Grant; Health; Health Status; Healthcare; Human; Immunity; Immunologics; Individual; Inequity; Infection; Inflammation; Inflammatory; Institution; Intervention; Investigation; Knowledge; Life Cycle Stages; Longevity; Medical; Medicine; Mentors; Mentorship; Methods; Modern Medicine; Modernization; Monitor; Morbidity - disease rate; National Institute of Allergy and Infectious Disease; Pathology; Pathway interactions; Patients; Pediatrics; Physicians; Population; Positioning Attribute; Preparation; Research; Research Personnel; Research Project Grants; Research Training; Residencies; Scholarship; Science; Scientist; Structure; Teaching Method; Time; Training; Training Programs; Underrepresented Minority; United States National Institutes of Health; Universities; Vocation; career; career development; clinical training; clinical translation; design; experience; flexibility; health care delivery; health care disparity; health disparity; health equity; human disease; improved; innovation; interest; medical schools; mortality; multidisciplinary; next generation; novel strategies; peer; prevent; programs; recruit; response; skill acquisition; skills; skills training; stem

Abstract: Despite the irreplaceable contributions of physician-scientists to clinical, the pipeline of clinician-scientist trainees remains on the decline. A critical barrier to the physician-scientist career is the lack of protected time and access to research mentorship available to physicians during clinical training. With the heightened acuity, volume and complexities of modern medicine, clinical training has increasingly focused on the acquisition and application of existing, rather than generation of new, knowledge. An unfortunate consequence of this shift in focus is the increasing compartmentalization of scientific training into fragments of time that are inadequate to provide the training and continuity needed to become proficient in the scientific investigation. The Tri- Institutional Stimulating Access to Research during Residency (Tri-I StARR) program seeks to remedy this deficiency by developing an integrated, longitudinal mentored research training program that will lead to the development, implementation, and evaluation of new clinical interventions to prevent, diagnose, treat and ameliorate health disparities of disorders of infectious, immunologic and inflammatory etiologies, with mentorship from across Weill Cornell Medicine, Rockefeller University, and Memorial Sloan Kettering. Tri-I- StARR will train residents on an integrated clinical-research pathway across 3 departments: Pediatrics, Medicine, and Pathology in areas along the full biomedical research continuum and include the themes of healthcare disparities and health and disease over the life course. The program proposes four training aims: (1) Acquisition of skills in the scientific method and design of hypothesis-based projects to address human diseases across the lifespan and their inequities, (2) Individualized, multidisciplinary mentorship in the design and completion of a research project, (3) Development of short, intermediate, and long term IDPs that integrate scientific and clinical training within and across career stages, and (4) Active engagement in horizontal and vertical networking among physician-scientists within and across career stages and institutions. The Tri-I-StARR will be led by an Executive Committee (EC) consisting of Kyu Rhee, MD PhD (Medicine), Sallie Permar, MD, PhD (Pediatrics), and Ethel Cesarman, MD (Pathology), an Expanded Executive Committee (EEC) of Residency Program Directors and Program Coordinators, and a team of 36 multi- departmental, multi-disciplinary, well-funded, and experienced faculty preceptors. Three Resident-Investigators each year will be supported for 12 months of research with the options to add an additional 12 months. Upon completion, trainees will be capable of transitioning to research-intense fellowship training, successfully competing for follow-on funding opportunities, including the K38, that will enable them to become the next generation of physicians leading and mentoring trainees in clinically-oriented research. This program will fulfill the urgent need for: 1) more full-time academic physician-researchers in medical schools throughout the country, and 2) innovations and clinical translation of novel strategies to improve health across the lifespan.

抽象的： 尽管医师科学家对临床有不可替代的贡献，但临床医生科学家的管道 学员仍在下降。医师科学家职业的关键障碍是缺乏受保护的时间 并在临床培训期间可以获得医生可提供的研究指导。随着敏锐度的提高 现代医学的数量和复杂性，临床培训越来越集中于收购和 应用现有的，而不是产生新知识。这种转变的不幸后果 重点是将科学培训越来越多地分为时间的碎片，这些时间不足 提供精通科学研究所需的培训和连续性。三 在居住期间（TRI-I Starr）计划期间，机构刺激访问研究的机会旨在纠正这一点 通过制定一项综合的，纵向指导的研究培训计划，这将导致 开发，实施和评估新的临床干预措施，以防止，诊断，治疗和 具有感染性，免疫学和炎症病因的疾病的改善健康差异， 来自Weill Cornell医学，洛克菲勒大学和纪念Sloan Kettering的指导。三 Starr将在三个部门的综合临床研究途径上培训居民：儿科： 医学和病理沿着完整的生物医学研究连续性，包括 人生过程中的医疗保健差异以及健康和疾病。该计划提出了四个培训目标： （1）在科学方法中获取技能和基于假设的项目以解决人类的技能 整个生命周期及其不平等的疾病，（2）设计中的个性化多学科指导 以及完成研究项目的完成，（3）开发短期，中级和长期IDP 将科学和临床培训整合到职业阶段和跨职业阶段，以及（4）积极参与 职业阶段和机构内外医师科学家之间的水平和垂直网络。 TRI-I-Starr将由由Kyu Rhee，MD博士（医学）组成的执行委员会（EC）领导。 医学博士Sallie Permar（儿科）和医学博士Ethel Cesarman（病理学） 居住计划董事和计划协调员的委员会（EEC），以及由36个多人组成的团队 部门，多学科，资金充足且经验丰富的教师主持人。三个居民评估者 每年将在12个月的研究中支持增加12个月的选择。之上 完成后，学员将能够过渡到研究强度奖学金培训，成功 争夺包括K38在内的后续资金机会，这将使他们成为下一个 领导和指导学员的医师从事临床研究的研究。这个程序将实现 迫切需要：1）整个医学院的更多全日制学术医师研究者 国家和2）新型策略的创新和临床翻译，以改善整个生命周期的健康。