University of Colorado Rocky Mountain NeuroNEXT (UNCOMON) Clinical Research Consortium.

科罗拉多大学落基山 NeuroNEXT (UNCOMON) 临床研究联盟。

基本信息

批准号：
10744629
负责人：
TIMOTHY A BENKE
金额：
$ 42.9万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-15 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10744629
关键词：
Acceleration Adult Advocacy Age Algorithms Area Behavioral Childhood Clinic Clinical Clinical Protocols Clinical Research Clinical Trials Clinical Trials Network Colorado Communication Community Outreach Contracts Data Databases Disease Enrollment Ensure Equity Ethics Faculty Funding Genetic Geography Goals Hospitals Immunologics Individual Informatics Infrastructure Institutional Review Boards Leadership Managed Care Medical Minority Minority Groups Monitor Movement Disorders Multi-Institutional Clinical Trial Native-Born Neurologic Neurology Neuropsychology Neurosciences Operations Research Patient Recruitments Patient Representative Patients Pediatric Hospitals Pediatric Neurology Pediatric Research Physicians Population Protocols documentation Qualifying Rare Diseases Recording of previous events Research Research Infrastructure Research Personnel Research Training Resources Rural Population Site Source Specialist Therapeutic Training Training Support Underserved Population Universities Work biobank care systems career clinical research site community engagement community partnership demographics design eHealth education resources experience hospital care investigator training medical specialties nervous system disorder neurogenetics neuroimaging neuromuscular neurosurgery next generation operation outreach patient advocacy group patient population patient retention pediatric department programs recruit skills support network therapeutic development

项目摘要

Effective clinical research into rare and ultra-rare neurologic and neurogenetic disorders requires a nationwide, collaborative network of neuroscience clinical research centers. The objective of the proposed University of Rocky Mountain NeuroNEXT Clinical Research Consortium (UNCOMON CRC) is to integrate expert from adult and child neurology, neurosurgery, neuroimaging, neuropsychology, and neurogenetics both the University of Colorado Hospital and Children's Hospital of Colorado on the University of Colorado Medical Campus into a large collaborative clinical research enterprise that exceeds start-up, retention, and operational goals of the NeuroNEXT network. The UNCOMON CRC is composed of recognized leaders in clinical research who have successfully participated in federally funded and multi-center clinical trials as well as local investigator-initiated therapeutic and biorepository The UNCOMON CRC will employ established clinical research and educational resources in conjunction a robust clinical research infrastructure to efficiently contribute to the NeuroNEXT network and advance the and research careers of the next generation of junior faculty nd fellows. We plan to achieve our goal the execution of the following specific aims: Aim 1: To establish a leadership network consisting of study adult and pediatric research directors, career enhancement director, DEI recruitment specialist, clinical coordinator, NeuroNEXT fellow, and operations manager; Aim 2: To establish an UNCOMON clinical consortium of collaborative co-investigators from adult and child neurology, neurosurgery, neuropsychology, and neurogenetics that encompass all subspecialty fields of clinical Aim 3: To establish a referral network to optimize recruitment and enhance outreach to minority and rural populations; and Aim 4: To develop and execute clinical research training and enhancement programs f or young i investigators using the collective expertise of the UNCOMON CRC. UNCOMON CRC will work efficiently to accelerate site qualification and IRB approval, employ multiple to optimize subject recruitment and retention, and carefully monitor research operations to ensure data a quality.

对罕见和超稀有神经系统疾病和神经遗传疾病的有效临床研究需要全国性的，神经科学临床研究中心的协作网络。拟议的落基山脉神经网络大学临床研究联盟（UNCOMON CRC）的目的是将成人和儿童神经病学，神经外科，神经影像，神经心理学，神经心理学和神经遗传学的专家整合到科罗拉多大学的科罗拉多大学的启动范围内，该研究的启动范围超过了科罗拉多大学，该进一步的启动范围是，该研究的范围超过了科罗拉多大学的启动，该目标将其纳入科罗拉多大学的启动，该目标将其运行范围扩展到科罗拉多大学的启动范围。 Neuronext网络。 Uncomon CRC由临床研究中公认的领导者组成，他们成功地参与了联邦资助和多中心临床试验以及当地研究人员发起的治疗和生物验证的CRC将采用既定的临床研究和教育资源，以有效地促进了临床研究的临床研究，并在进行了良好的临床研究，并为有效的临床研究提供了促进的临床研究，并将初级教师和研究员。我们计划实现以下特定目标的执行：目标1：建立一个由研究成人和儿科研究主管组成的领导网络，职业增强总监，DEI招聘专家，临床协调员，Neuronext研究员和运营经理；目的2：建立一个来自成人和儿童神经病学，神经外科，神经心理学和神经遗传学的协作共同入侵者的临床联盟，该联盟涵盖了临床目标的所有亚科领域3：建立转介网络以优化招聘并增强对少数群体和农村人口的推广；目标4：使用Uncomon CRC的集体专业知识，开发和执行I研究者的临床研究培训和增强计划。 UNCOMON CRC将有效地提高现场资格和IRB批准，雇用多个来优化受试者招聘和保留率，并仔细监控研究操作以确保数据质量。