The Mayo Clinic NeuroNEXT Clinical Research Site

梅奥诊所 NeuroNEXT 临床研究网站

基本信息

批准号：
10743328
负责人：
Nathan P Staff
金额：
$ 46.93万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-15 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10743328
关键词：
Acceleration Adult Applications Grants Arizona Awareness Caring Child Clinic Clinical Clinical Research Clinical Sciences Clinical Trials Communities Community Trial Contracts Country Diagnosis Disease Education Eligibility Determination Enrollment Ensure Faculty Florida Funding Mechanisms Geography Goals Grant Infrastructure Institution Institutional Review Boards Intervention Leadership Life Cycle Stages Midwestern United States Minnesota Mission Modernization National Center for Advancing Translational Sciences National Institute of Neurological Disorders and Stroke Neurologic Neurologist Neurology Neurosciences Participant Patients Population Population Heterogeneity Positioning Attribute Principal Investigator Process Protocols documentation Publishing Rare Diseases Recording of previous events Research Research Personnel Science Site Structure Therapeutic Time Training Training Programs Translational Research Translations United States United States National Institutes of Health Work career development clinical center clinical infrastructure clinical research site experience improved innovation member nervous system disorder next generation novel therapeutics pediatric patients programs rare condition research facility rural setting synergism therapeutic development trial design

项目摘要

Mayo Clinic, which serves ~1.3M patients annually, has a history of excellence in clinical research and clinical trials. Its state-of-the-art research facilities in Rochester, Minnesota, Jacksonville, Florida, and Scottsdale, Arizona enable coordinated clinical trials in the upper Midwest, Southeast, and Southwest United States. The Department of Neurology, which has over 200 child and adult neurologists, has an enterprise-wide leadership structure that supports its integrated practice, research, and education mission. Mayo Clinic Neurology cares for >90,000 adult and pediatric patients annually and has a robust clinical research enterprise. Departmental faculty have clinical expertise and clinical trial experience across the full spectrum of neurological diseases, including rare and ultra-rare conditions. Mayo Clinic is ideally positioned to provide NeuroNEXT the diverse patients with unmet needs and the clinical trialists with expertise in these diseases. Investigator-initiated clinical trials by Mayo neurology faculty will be directed towards NeuroNEXT funding mechanisms. This grant application aims to support, expand, and innovate neuroscience clinical trial activities at all Mayo Clinic sites by providing the infrastructure to ensure robust integration within NeuroNEXT, while leveraging our institutional strengths. Furthermore, the grant will support an innovative program to train the next generation of clinical trialists to thrive in an evolving landscape of innovative trial design and modern regulatory science.

Mayo Clinic 每年为约 130 万名患者提供服务，在临床研究和临床试验方面拥有卓越的历史。其位于明尼苏达州罗切斯特、佛罗里达州杰克逊维尔和亚利桑那州斯科茨代尔的最先进的研究设施能够在美国中西部北部、东南部和西南部进行协调一致的临床试验。神经病学系拥有 200 多名儿童和成人神经科医生，拥有一个全企业范围的领导结构，支持其综合实践、研究和教育使命。 Mayo Clinic 神经科每年为超过 90,000 名成人和儿童患者提供护理，并拥有强大的临床研究企业。系内教师拥有各种神经系统疾病（包括罕见和超罕见疾病）的临床专业知识和临床试验经验。 Mayo Clinic 处于理想的位置，可以为需求未得到满足的不同患者和具有这些疾病专业知识的临床试验人员提供 NeuroNEXT。由梅奥神经病学教授发起的研究者发起的临床试验将针对 NeuroNEXT 资助机制。该拨款申请旨在通过提供基础设施来确保 NeuroNEXT 内的稳健整合，同时利用我们的机构优势，支持、扩大和创新所有 Mayo Clinic 站点的神经科学临床试验活动。此外，这笔赠款将支持一项创新计划，以培训下一代临床试验人员，使其在创新试验设计和现代监管科学不断发展的环境中茁壮成长。