Mentoring Across Disciplines: Aging and Infectious Diseases with a Focus on Mobility

跨学科指导：以流动性为重点的老龄化和传染病

• 批准号: 10757167
• 负责人: Kristine Mace Erlandson
• 金额: $ 19.19万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10757167
• 关键词: Acceleration; Address; Adherence; Adult; Age; Aging; Award; Behavioral; Biological; Cardiovascular system; Clinic; Clinical; Clinical Management; Clinical Trials; Communicable Diseases; Communities; Data; Development Plans; Discipline; Dissemination and Implementation; Effectiveness of Interventions; Elderly; Elements; Ensure; Epidemiology; Evaluation; Exercise; Feedback; Funding; Future; Geriatric Assessment; Geriatrics; Goals; Group Interviews; Guidelines; HIV; Health; Impairment; Income; Individual; Institution; Interval training; Intervention; Interview; Knowledge; Leadership; Location; Lower Extremity; Measurement; Measures; Mentors; Mentorship; Methods; Mid-Career Clinical Scientist Award (K24); Minority Groups; Modality; Modeling; Modification; Muscle; National Institute on Aging; Outcome; Outcome Assessment; Parents; Participant; Patients; Persons; Physical Function; Physical activity; Positioning Attribute; Poverty; Process; Provider; Randomized; Reach, Effectiveness, Adoption, Implementation, and Maintenance; Research; Research Personnel; Risk; Role; Scanning; Science; Structure; Surveys; Text Messaging; Thick; Time; Training; Upper Extremity; Work; acceptability and feasibility; aged; career; career development; clinical care; community based research; design; effective intervention; evidence base; exercise intensity; exercise intervention; exercise prescription; experience; functional decline; health data; health disparity; health equity; healthy aging; implementation research; improved; informant; member; motivational enhancement therapy; muscle form; patient oriented; patient oriented research; portability; pragmatic implementation; preference; preservation; prevent; programs; resistance exercise; social culture; systematic review; tool; ultrasound; uptake

PROJECT SUMMARY This K24 Mid-Career Mentoring Award supports my further career development and 50% protected time for mentoring and research. My patient-oriented research has bridged the intersection between HIV and geriatric medicine, through which I have developed a research program to describe the epidemiology and underlying mechanisms of HIV and aging, and introduced interventions focused on the successful aging of people with HIV (and other infectious diseases). Through the K24 award, I propose to take my research from the bench and the bedside into the clinic and community by gaining training in dissemination/implementation and community-based research principles (Training Aim 1) and health equity and inclusion in research, mentorship, and leadership (Training Aim 2). To provide hands-on training for these career development aims, I will focus on improving methods for measurement of muscle mass and quality in physical activity interventions (Aim 1). In Aim 2, I will work to improve methods for pragmatic and feasible interventions through a systematic review of existing interventions, input from key informants, and an environmental scan, with a focus on what is feasible and acceptable. We will conduct a systematic review and individual or group interviews, and used mixed methods to incorporate these findings with data from the parent R01, HEALTH. Lastly, I will use knowledge from Aims 1 and 2 to enhance existing physical activity programs for greater dissemination and implementation (Aim 3). I will be supported by mentors with expertise in dissemination/ implementation and health equity, in addition to three ongoing mentors with cross-disciplinary research programs, outstanding mentorship accolades, and leadership positions within their institutions. Lastly, my institution has provided me with the additional support, most critically in time protected from additional clinical or administrative duties. In summary, the proposed K24 will leverage my current R01 to serve as a training platform for trainees and incorporate my career development objectives, ultimately advancing the science of interventions to preserve physical function in older people with HIV and support patient-oriented researchers.

项目摘要 这项K24中级指导奖支持我进一步的职业发展，并保护了50％的保护时间 指导和研究。我以患者为导向的研究弥合了艾滋病毒和老年医生之间的交叉点 我通过该医学制定了一项研究计划，以描述流行病学和基础 艾滋病毒和衰老的机制，并引入了干预措施，重点是 艾滋病毒（和其他传染病）。通过K24奖，我建议从板凳上获得研究 以及通过获得传播/实施培训和 基于社区的研究原则（培训目标1）以及研究中的健康平等以及研究中的包容性， 指导和领导力（培训目标2）。为这些职业发展提供动手培训 目的，我将专注于改进测量肌肉质量和体育锻炼质量的方法 干预措施（目标1）。在AIM 2中，我将努力通过通过 对现有干预措施的系统审查，关键线人的输入以及环境扫描，并具有 专注于可行和可接受的内容。我们将进行系统的审查以及个人或小组 采访，并使用混合方法将这些发现与父母R01的数据结合在一起。 最后，我将使用目标1和2的知识来增强现有的体育活动计划，以提高更多 传播和实施（目标3）。我将得到具有传播专业知识的导师的支持/ 除了三位正在进行的跨学科研究的导师外，实施和健康公平 计划，杰出的指导荣誉以及其机构中的领导职务。最后，我的 机构为我提供了额外的支持，最严重的及时保护了额外的临床 或行政职责。总而言之，拟议的K24将利用我目前的R01作为培训 学员的平台并结合了我的职业发展目标，最终推进了科学 干预措施以保护艾滋病毒的老年人并支持以患者为导向的研究人员进行干预措施。