Advancing Assessment of Episodic Disability to Enhance Healthy Aging among Adults with HIV: Developing a Short-Form HIV Disability Questionnaire (HDQ) for use in Clinical Practice

推进偶发性残疾评估，以促进艾滋病毒感染者的健康老龄化：制定用于临床实践的简短艾滋病毒残疾问卷 (HDQ)

• 批准号: 10002166
• 负责人: Kristine Mace Erlandson
• 金额: $ 17.16万
• 依托单位: UNIVERSITY OF TORONTO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10002166
• 关键词: Adult; Advisory Committees; Age; Aging; Canada; Caring; Clinic; Clinic Visits; Clinical; Clinical Management; Collaborations; Colorado; Communities; Consequences of HIV; Consultations; Data; Databases; Disability Evaluation; Effectiveness of Interventions; Elderly; Evaluation; Face; Female; Foundations; Future; Goals; HIV; Health; Health Personnel; Health Status; Health system; Individual; International; Intervention; Interview; Ireland; Measurement; Measures; Nature; Outcome; Participant; Patient Outcomes Assessments; Phase; Pilot Projects; Prevalence; Property; Psyche structure; Psychometrics; Questionnaires; Recommendation; Research; Resource Allocation; Services; Severities; Site; Standardization; Structure; Tablets; Testing; Time; Uncertainty; United States; Validation; Validity and Reliability; Woman; Work; age group; clinical practice; clinical research site; design; disability; experience; healthy aging; instrument; multiple chronic conditions; patient-clinician communication; phase 1 study; practice setting; rehabilitation research; social; social inclusion; trend; uptake

ABSTRACT The purpose of the proposed study is to develop and pilot the implementation of a short-form HIV-specific disability questionnaire to promote healthy aging among adults aging with HIV. Specific aims are: 1) To develop and assess the utility of a new short-form HIV-specific disability questionnaire across multiple clinical practice settings with older adults with HIV, and 2) To pilot the implementation of the new short-form HIV-specific disability questionnaire, and assess its measurement properties while collecting foundational data on the presence, severity and episodic nature of disability among adults aging with HIV and multimorbidity in the United States, Canada and Ireland. Standardized patient reported outcomes (PROs) designed to capture the nature and extent of disability and its fluctuation over time are critical to guide the provision of timely and appropriate care for adults aging with HIV. In an earlier phase of work, we developed a 69-item Patient Reported Outcome (PRO), called the HIV Disability Questionnaire (HDQ) and demonstrated its reliability and validity among adults living with HIV in Canada and Ireland. As an increasing number of adults age with HIV and multimorbidity, there is a critical need for a brief yet comprehensive assessment of disability that can be routinely and easily administered across health systems in clinical practice. In Phase 1 of this study, we will use psychometric (Rasch analysis) and clinical approaches to develop a short-form version of the HDQ (SF-HDQ). We will then use a combination of quantitative (questionnaires) and qualitative (interviews) with adults aging with HIV and HIV health providers to assess sensibility (face and content validity), utility, and optimal use of the SF-HDQ in clinical practice across three clinical sites in Denver Colorado, Toronto Canada and Dublin Ireland. In Phase 2, we will conduct a cross-sectional pilot study to examine the implementation and assess the measurement properties of the SF-HDQ with adults aging with HIV across the three health systems. Outcomes will yield the first known short form HIV-specific disability PRO developed through international, academic-community collaboration to assess prevalence and impact of episodic disability. Future universal measurement of disability may contribute to ongoing clinical management, specifically tracking of episodic disability trends and evaluation of interventions to inform allocation of resources to better promote healthy aging with HIV.

抽象的 拟议的研究的目的是开发和试行实施短形式 艾滋病毒特异性的残疾问卷，以促进患有艾滋病毒的成年人衰老的健康衰老。 具体目的是：1）开发和评估新的短形式HIV特异性残疾的实用性 与HIV老年人的多个临床练习环境中的问卷，以及2） 实施新的短形式HIV特异性残疾问卷，并评估其 在收集有关存在，严重性和 艾滋病衰老的成年人衰老的残疾情节性质 州，加拿大和爱尔兰。标准化患者报告的结果（PRO） 捕获残疾的性质和程度及其随着时间的流逝而言至关重要 为患有艾滋病毒衰老的成年人提供及时和适当的护理。在早期的工作阶段， 我们开发了一个69个项目的患者报告的结果（PRO），称为HIV残疾 问卷（HDQ），并证明了其在艾滋病毒中的成年人的可靠性和有效性 加拿大和爱尔兰。随着艾滋病毒和多种病态的成年人年龄越来越多，那里 对可以进行简短而全面的残疾评估的迫切需要，这是常规的， 在临床实践中很容易跨卫生系统管理。在本研究的第一阶段，我们将 使用心理测量学（RASCH分析）和临床方法来开发短形式的版本 HDQ（SF-HDQ）。然后，我们将使用定量（问卷）和 与艾滋病毒和艾滋病毒健康提供者衰老的成年人衰老的定性（访谈）评估敏感性 （面部和内容有效性），实用程序以及SF-HDQ在整个临床实践中的最佳使用 在丹佛科罗拉多州，加拿大多伦多和都柏林爱尔兰的三个临床场所。在第二阶段，我们将 进行横断面试验研究以检查实施并评估 SF-HDQ的测量特性，成年人在三个健康中衰老的HIV衰老 系统。结果将产生第一个已知的简短形式的HIV特异性残疾人Pro 通过国际学术社区合作，以评估 情节残疾。未来的普遍测量残疾可能有助于持续的临床 管理，特别跟踪情节残疾趋势和干预措施的评估 告知资源分配，以更好地促进艾滋病毒的健康衰老。