Harvard School of Dental Medicine Collaborative Clinical Practice-based REsearch Program for DENTal Schools (H-CREDENT)

哈佛大学牙科医学院牙科学院基于临床实践的合作研究计划 (H-CREDENT)

基本信息

批准号：
10754738
负责人：
WILLIAM V GIANNOBILE
金额：
$ 85.91万
依托单位：
HARVARD MEDICAL SCHOOL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-13 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10754738
关键词：
Active Learning Address Age Aptitude Artificial Intelligence Basic Science Clinical Clinical Research Collaborations Communities Complement Dedications Dental Dental Care Dental Education Dental Faculty Dental General Practice Dental Schools Dental Students Dentistry Development Enrollment Face Faculty Fostering Genetic Genomics Goals Health Alliance Health Personnel Health Sciences Healthcare Individual Institution Investigation Learning Machine Learning Massachusetts Measures Medicine Mentors Mentorship Mission National Institute of Dental and Craniofacial Research Neighborhood Health Center New England Oral Oral health Outcome Pain Pain management Participant Patients Pharmacy facility Population Post-Procedural Pain Postdoctoral Fellow Postoperative Pain Practice based research Predictive Factor Private Practice Problem Solving Program Development Provider Research Research Design Research Methodology Research Personnel Risk Risk Factors Salivary Scientific Inquiry Site Stratification Students Training Training Programs Translational Research Universities Work care burden career catalyst clinical care clinical investigation clinical practice college craniofacial demographics doctoral student experience follow-up health care delivery high risk innovation inter-institutional longitudinal, prospective study machine learning method member multidisciplinary next generation pain-related disability patient stratification peer practice-based research network programs prospective psychosocial public health research recruit research faculty risk stratification skill acquisition

项目摘要

Project Summary/Abstract The Harvard School of Dental Medicine Collaborative Clinical Practice-based REsearch Program for DENTal Schools (H-CREDENT) will embark on an innovative, multidisciplinary practice-based research program to engage dental students and residents with research and clinical-based faculty to address the challenge of pain management in dentistry. H-CREDENT is a partnership amongst HSDM, University of New England, Massachusetts College of Pharmacy & Health Sciences, Meharry University, Charles River Community Health Center, and Cambridge Health Alliance. The program provides didactic and hands-on clinical research opportunities to deliver an experiential-learning/training for pre-/postdoctoral students and clinical/research faculty at these sites. Leveraging the unique diversity in the provider/patient communities brought together by this collaboration, H-CREDENT strives to prepare the next-generation oral healthcare providers through the conduct of practice-based clinical research to enhance precision oral healthcare delivery. H-CREDENT will work towards this goal by accomplishing 2 aims: Aim 1: Establishment of clinical research skills development program that will train next-generation clinical scholars in practice-based research networks (PBRNs). Skills development will be advanced via a) coursework in clinical research study design and PBR, complemented by b) unique pod-based mentorship program for experiential learning. Courses will be developed by HSDM investigators in partnership with Harvard Catalyst, national PBRN, and a premier network of private practice clinicians with extensive experience in clinical research. The courses will be taken by H- CREDENT trainees from all collaborating sites, and each mentoring pod will comprise research-/clinical-focused faculty and pre-/ postdoctoral trainees from all institutions to promote strong mentorship relationships, both vertically (e.g., student/faculty) and laterally (e.g., peer-peer) across institutions. Aim 2: A PBRN investigation to engage dental student and faculty providers to determine risk factors for developing pain following invasive dental procedures and stratify patients based on demographic, psychosocial, and genetic factors. We will a) determine risk factors predicting pain after dental procedures and b) how well the dental providers can predict the patients’ pain experience and if biases influence this prediction, and c) identify patients as low-/ high-risk for developing post-procedural pain through patient stratification by applying artificial intelligence/ machine learning methods. This prospective longitudinal study will take place at all sites, where pre-/postdoctoral students will recruit/enroll, perform dental procedures, and follow up with patients, under the guidance of their clinical mentor. Differential experiences by H-CREDENT trainees across institutions will be shared via mentoring pods to integrate and reinforce learnings from the classroom and direct participation in clinical research. Through these activities, H-CREDENT will foster a culture of scientific inquiry to prepare dental providers with aptitude for conducting effective practice-based clinical research.

项目概要/摘要哈佛大学牙科医学院基于临床实践的合作研究项目牙科学校 (H-CREDENT) 将开展一项创新的、多学科的、基于实践的研究计划让牙科学生和住院医师与研究和临床教师合作，应对以下挑战 H-CREDENT 是新英格兰大学 HSDM 之间的合作伙伴关系。马萨诸塞州药学与健康科学学院、梅哈里大学、查尔斯河社区健康中心该计划提供教学和实践临床研究。为博士前/后学生和临床/研究提供体验式学习/培训的机会利用这些地点的提供者/患者社区的独特多样性。通过此次合作，H-CREDENT 致力于通过以下方式为下一代口腔保健提供者做好准备：进行基于实践的临床研究，以增强精准的医疗保健口腔递送。 H-CREDENT 将通过实现 2 个目标来实现这一目标：目标 1：建立临床研究技能发展计划将培训下一代临床学者进行基于实践的研究网络（PBRN）的技能发展将通过 a) 临床研究设计和课程作业来推进。 PBR 辅以 b) 独特的基于 pod 的体验式学习指导计划。由 HSDM 研究人员与Harvard Catalyst、国家 PBRN 和主要网络合作开发具有丰富临床研究经验的私人诊所的课程将由 H- 参加。来自所有合作地点的 CREDENT 学员，每个指导小组都将包括以研究/临床为重点的人员来自所有机构的教师和博士前/博士后学员，以促进牢固的指导关系，目标 2：跨机构的纵向（例如学生/教师）和横向（例如同行）调查。让牙科学生和教职人员参与进来，确定侵入性手术后发生疼痛的风险因素我们将a) 进行牙科手术并根据人口统计、社会心理和遗传因素对患者进行分层。确定预测牙科手术后疼痛的风险因素，以及 b) 牙医的预测能力如何患者的疼痛经历以及偏差是否影响这一预测，以及 c) 将患者识别为低/高风险应用人工智能/机器学习，通过患者分层来产生术后疼痛这项前瞻性纵向研究将在所有博士前/后学生将进行的地点进行。在临床导师的指导下招募/登记、执行牙科手术并跟进患者。各机构的 H-CREDENT 学员的不同经验将通过指导小组分享通过这些整合和强化课堂学习以及直接参与临床研究。活动中，H-CREDENT 将培育一种科学探究文化，培养具备以下能力的牙科服务提供者：进行有效的基于实践的临床研究。