Differential impacts of water insecurity on diet and body composition throughout the life course

水不安全对整个生命过程中饮食和身体成分的不同影响

• 批准号: 10749236
• 负责人: Joshua D Miller
• 金额: $ 3.95万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10749236
• 关键词: Address; Adolescence; Adolescent; Adult; Affect; Age; Agriculture; Body Composition; Body fat; Body mass index; Breast Feeding; Caregivers; Child; Childhood; Cohort Studies; Communicable Diseases; Complement; Consumption; Data; Development; Diet; Dimensions; Discipline; Disease; Eating; Ecuador; Educational Curriculum; Environment; Epidemiologic Methods; Epidemiology; Equation; Exposure to; Family; Focus Groups; Food; Food production; Future; Gastrointestinal Diseases; Growth; Health; Health Surveys; Home; Household; Income; Individual; Infant; Intake; Interview; Island; Knowledge; Life Cycle Stages; Malnutrition; Measures; Mentorship; Methods; Modeling; Nutrient; Nutrition Surveys; Nutritional; Obesity; Overweight; Pathway interactions; Personal Satisfaction; Philippines; Physical activity; Preparation; Procedures; Process; Production; Public Health; Reporting; Research; Research Personnel; Resources; Risk; Role; Safety; Secure; Site; Structure; Surveys; Systems Biology; Techniques; Time; Unhealthy Diet; United States; Water; Weight Gain; Work; career; comparative; cooking; dietary; dietary guidelines; early childhood; enteric pathogen; experience; food environment; food insecurity; food preparation; improved; indexing; infancy; innovation; lens; multilevel analysis; nutrition; skills; sugar; sweetened beverage; water quality; waterborne pathogen; well water

PROJECT SUMMARY/ABSTRACT Unreliable access to safe and sufficient water for all household uses (i.e., water insecurity) is a common but understudied public health issue. Although water is itself a critical nutrient that is essential for agricultural production, food preparation, and hygienic practices that reduce exposure to enteric pathogens, few studies have examined the role of water insecurity in nutrition; most consider water quality only. A more holistic conceptualization of water insecurity could reveal important pathways by which water accessibility, reliability, and adequacy impact diet and health. Water insecurity presents substantial barriers to cooking nutrient-dense foods, which often require considerable water to be made palatable and safe for consumption. Qualitative studies have reported that water insecurity limits breastfeeding duration and undermines the ability of caregivers to prepare preferred complementary foods. Individuals experiencing water insecurity are also more likely to substitute water with sugar-sweetened beverages, plausibly contributing to weight gain and increased risk of overweight and obesity. The proposed project seeks to expand upon this formative work by examining the extent to which differential exposure to water insecurity impacts diet quality and body composition throughout the life course. A mixed-methods approach is required to comprehensively understand how water insecurity manifests at the household level and subsequently impacts nutritional well-being. The proposed project will therefore use qualitative data to complement quantitative data from 2 existing cohort studies that comprehensively measured water insecurity and diet among infants, children, adolescents, and adults on San Cristóbal Island, Ecuador and in Cebu, Philippines. Specifically, the project aims to qualitatively describe how issues with water availability, accessibility, and use impact food production, purchase, and preparation (Aim 1). Multi-level modeling will be used to assess whether household water insecurity undermines child diet quality (Aim 2) and longitudinal structural equation modeling will be applied to evaluate how changes in household water insecurity throughout early development impact adiposity (Aim 3). The project will address a recognized knowledge gap within the field by using advanced statistical procedures to model water insecurity as a multidimensional, time-varying exposure. Findings from this work have the potential to reveal new targets for addressing the growing burden of malnutrition. Additionally, the proposed rigorous curriculum in nutrition and epidemiology, as well as mentorship from thought leaders in the water and nutrition sectors, will prepare the applicant for an academic career in global nutrition.

项目摘要/摘要 对于所有家庭用途（即水不安全感），获得安全和足够的水是一种常见，但 研究的公共卫生问题。尽管水本身是一种至关重要的营养，对于农业至关重要 生产，食物制备和卫生实践减少了促进病原体的暴露，很少的研究 已经检查了水不安全感在营养中的作用；大多数仅考虑水质。更加整体 水不安全感的概念化可能会揭示重要的途径，可靠性，可靠性， 充足性影响饮食和健康。 水不安全感呈现出烹饪营养密集的食物的实质性障碍，这通常需要 可以使大量的水变得可口，可以安全地消费。定性研究报告了水 不安全感限制了母乳喂养的持续时间，并破坏了护理人员准备首选的能力 完全食物。经历水不安全感的人也更有可能用 糖粉的品种，合理地导致体重增加和增加超重和肥胖的风险。 拟议的项目试图通过检查差异的程度来扩展这项形成性工作 在整个生活过程中，暴露于水不安全感会影响饮食质量和身体成分。 需要一种混合方法的方法来全面了解水不安全感如何表现在 家庭水平，随后影响营养健康。因此，拟议的项目将使用 定性数据以补充2项现有队列研究的定量数据，这些数据全面测量 在圣克里斯托岛，厄瓜多尔和 在菲律宾宿雾。具体而言，该项目旨在定性地描述水的问题如何 可访问性并使用影响粮食生产，购买和准备（AIM 1）。多层建模将是 用于评估家庭水不安全感是否破坏了儿童饮食质量（AIM 2）和纵向 结构方程建模将用于评估家庭水不安全感的变化如何 早期发展影响肥胖（AIM 3）。 该项目将通过使用高级统计程序来解决该领域中公认的知识差距 将水不安全感建模为多维，时变的暴露。这项工作的发现有 揭示新目标以解决营养不良的燃烧的潜力。另外，提议 营养和流行病学的严格课程，以及水中思想领袖的指导力量 营养领域，将为申请人做好准备，从而为全球营养学业的学术生涯做好准备。