TJU-JNMC Global Network for Women's and Children's Health Research Unit

TJU-JNMC 全球妇女儿童健康网络研究中心

基本信息

批准号：
10746058
负责人：
RICHARD J DERMAN
金额：
$ 61.6万
依托单位：
THOMAS JEFFERSON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-07-01 至 2030-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10746058
关键词：
Academic Medical Centers Accreditation Achievement Address Anemia Area Artificial Intelligence Catchment Area Cessation of life Child Child Health Child Mortality Clinical Research Clinical Trials Collaborations Committee Membership Communicable Diseases Communication Communities Community Medicine Community Networks Country Data Data Set Development Discipline of obstetrics Ensure Epidemiology Evidence based intervention Faculty Family Fostering Funding Opportunities Future Goals Growth Gynecology Health Health Personnel Health Policy Health Status Health financing Health system Healthcare High Prevalence Histopathology India Infant Infrastructure Intervention Knowledge Laboratories Lactation Leadership Maternal Mortality Maternal and Child Health Methods Monitor Morbidity - disease rate Multi-Institutional Clinical Trial National Institute of Child Health and Human Development Neonatology Newborn Infant Nurses&apos Aides Observational Study Outcomes Research Participant Pediatrics Persons Pharmacology Policies Population Population Heterogeneity Pregnancy Outcome Pregnant Women Premature Birth Procedures Productivity Professional counselor Protocols documentation Public Health Qualitative Research Recording of previous events Registries Reproducibility Research Research Design Research Personnel Resource-limited setting Resources Safety Site Strategic Planning Students Sustainable Development Target Populations Techniques Translational Research Universities Woman Women Status Workforce Development adverse outcome antimicrobial biobank clinical research site community engagement cost effective data access data sharing design disability experience fetal medicine follow-up health assessment implementation research improved infant outcome innovation low and middle-income countries maternal outcome medical schools member microbiome mortality neonatal health neonatal outcome neurodevelopment new technology offspring peer pregnant recruit retention rate scale up social successful intervention

项目摘要

Project Summary/Abstract Building on a history of more than two decades of successful collaboration among Thomas Jefferson University (TJU), Jawaharlal Nehru Medical College (JNMC), and the NICHD Global Network for Women's and Children's Health Research, we seek to ensure the continued growth, development, and sustainability of our partnership via the next cycle of the Global Network (GN). Specific project aims include: • Provide experienced leadership within the GN fostering innovation, research excellence, and conduct of common protocols addressing major causes of maternal/child morbidity/mortality in LMICs, and incorporating implementation research aiming to scale up successful interventions and influence public health policy; • Identify and address gaps in maternal and child health research, utilizing a team-based approach to design, develop, implement, and evaluate promising health interventions, focusing on those addressing public health crises that impact the health of pregnant/lactating women and their offspring, and promoting progress toward achievement of the NICHD Strategic Plan 2020 and the 2030 Sustainable Development Goals for maternal, newborn, and under-5 mortality, and, as appropriate, health financing, and workforce development; • Engage local stakeholders by continuing to involve the Ministries of Health at the local, state, and national level; incorporating ASHA workers and auxiliary nurses into the research team (with approval of the MOH); and establishing a local Community Engagement Board comprising lay community members to provide local perspective on research outcomes of most benefit to participants, support dissemination of research findings, and promote translation of research evidence into practice; • Expand research capacity and catchment areas within Karnataka, as well as to other states in India – specifically Maharashtra, Rajasthan, and Odisha – resulting in greater generalizability of findings to all regions and populations of the country and other low resource settings globally; • Conduct GN approved common protocols with high recruitment and retention rates encompassing a range of study designs (e.g., RCTs, formative, translational, mixed methods, observational, and implementation research) initiated by GN investigators, as well as those proposed by outside investigators; • Apply the guiding principles of NICHD-supported multi-site clinical research which are: 1) Enhance rigor and reproducibility, 2) Promote greater availability of multisite clinical trial infrastructure to support trials from a wider range of investigators, 3) Facilitate data sharing and access to biospecimens, 4) Facilitate greater involvement of diverse populations in multisite clinical trials; • Disseminate research findings with the goal of influencing health policy and system changes and to scale up evidence-based interventions to promote meaningful and sustainable health improvements.

项目摘要/摘要建立在托马斯·杰斐逊大学（Thomas Jefferson University）成功合作二十年的历史的基础上（TJU），Jawaharlal Nehru医学院（JNMC）和NICHD全球妇女和儿童网络健康研究，我们试图确保我们的伙伴关系的持续增长，发展和可持续性通过全球网络（GN）的下一个周期。特定项目的目的包括： •在GN促进创新，研究卓越和行为中提供经验丰富的领导解决LMIC中母性/儿童发病率/死亡率的主要原因的常见方案，并纳入实施研究旨在扩大成功的干预措施并影响公共卫生政策； •使用基于团队的方法来识别和解决母校和儿童健康研究中的差距设计，开发，实施和评估承诺的健康干预措施，重点是向公众致辞影响孕妇/哺乳期妇女及其后代健康的健康危机，并促进进步实现2020年NICHD战略计划和2030年的可持续发展目标孕产妇，新生儿和5岁以下的死亡率，以及适当的卫生融资和劳动力发展； •通过继续参与当地，州和国家的卫生部，吸引当地利益相关者等级;将ASHA工人和辅助护士纳入研究小组（经MOH的批准）；并建立当地社区参与委员会完成外行社区成员以提供本地对参与者最大收益的研究结果的观点，支持研究结果的传播，并将研究证据的翻译转化为实践； •扩大卡纳塔克邦以及印度其他州的研究能力和集水区 - 马哈拉施特拉邦，拉贾斯坦邦和奥里萨邦 - 使所有地区的发现更具普遍性以及该国和其他资源较低的人口在全球范围内； •执行GN批准具有高招聘和保留率的共同协议，包括研究设计范围（例如，RCT，形成性，翻译，混合方法，观察性和实施研究）由GN研究人员以及外部研究人员提出的研究； •应用NICHD支持的多站点临床研究的指导原则：1）增强严格和可重复性，2）促进更大的多站点临床试验基础设施的可用性，以支持来自更广泛的调查人员，3）促进数据共享和访问生物测量，4）促进更大的潜水员种群参与多站点临床试验； •以影响健康政策和系统变化的目的传播研究结果并进行扩展加强基于证据的干预措施，以促进有意义和可持续的健康改善。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Neonatal deaths in rural Karnataka, India 2014-2018: a prospective population-based observational study in a low-resource setting.

DOI：
10.1186/s12978-020-01014-6
发表时间：
2020-11-30
期刊：
Reproductive health
影响因子：
3.4
作者：
Dhaded SM;Somannavar MS;Moore JL;McClure EM;Vernekar SS;Yogeshkumar S;Kavi A;Ramadurg UY;Nolen TL;Goldenberg RL;Derman RJ;Goudar SS
通讯作者：
Goudar SS

Prediction and Prevention of Spontaneous Preterm Birth: ACOG Practice Bulletin, Number 234.

DOI：
10.1097/aog.0000000000004612
发表时间：
2021-12-01
期刊：
Obstetrics and gynecology
影响因子：
7.2
作者：
Hoffman MK
通讯作者：
Hoffman MK

Hemoglobin concentrations and adverse birth outcomes in South Asian pregnant women: findings from a prospective Maternal and Neonatal Health Registry.

DOI：
10.1186/s12978-020-01006-6
发表时间：
2020-11-30
期刊：
Reproductive health
影响因子：
3.4
作者：
Ali SA;Tikmani SS;Saleem S;Patel AB;Hibberd PL;Goudar SS;Dhaded S;Derman RJ;Moore JL;McClure EM;Goldenberg RL
通讯作者：
Goldenberg RL

Global Maternal and Child Health:: A Research Partnership's Approach for Addressing Challenges and Reducing Health Disparities in Developing Countries.

全球妇幼健康：研究伙伴关系应对发展中国家挑战和减少健康差距的方法。