TJU-JNMC Global Network for Women's and Children's Health Research Unit

TJU-JNMC 全球妇女儿童健康网络研究中心

• 批准号: 10746058
• 负责人: RICHARD J DERMAN
• 金额: $ 61.6万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2030-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10746058
• 关键词: Academic Medical Centers; Accreditation; Achievement; Address; Anemia; Area; Artificial Intelligence; Catchment Area; Cessation of life; Child; Child Health; Child Mortality; Clinical Research; Clinical Trials; Collaborations; Committee Membership; Communicable Diseases; Communication; Communities; Community Medicine; Community Networks; Country; Data; Data Set; Development; Discipline of obstetrics; Ensure; Epidemiology; Evidence based intervention; Faculty; Family; Fostering; Funding Opportunities; Future; Goals; Growth; Gynecology; Health; Health Personnel; Health Policy; Health Status; Health financing; Health system; Healthcare; High Prevalence; Histopathology; India; Infant; Infrastructure; Intervention; Knowledge; Laboratories; Lactation; Leadership; Maternal Mortality; Maternal and Child Health; Methods; Monitor; Morbidity - disease rate; Multi-Institutional Clinical Trial; National Institute of Child Health and Human Development; Neonatology; Newborn Infant; Nurses' Aides; Observational Study; Outcomes Research; Participant; Pediatrics; Persons; Pharmacology; Policies; Population; Population Heterogeneity; Pregnancy Outcome; Pregnant Women; Premature Birth; Procedures; Productivity; Professional counselor; Protocols documentation; Public Health; Qualitative Research; Recording of previous events; Registries; Reproducibility; Research; Research Design; Research Personnel; Resource-limited setting; Resources; Safety; Site; Strategic Planning; Students; Sustainable Development; Target Populations; Techniques; Translational Research; Universities; Woman; Women Status; Workforce Development; adverse outcome; antimicrobial; biobank; clinical research site; community engagement; cost effective; data access; data sharing; design; disability; experience; fetal medicine; follow-up; health assessment; implementation research; improved; infant outcome; innovation; low and middle-income countries; maternal outcome; medical schools; member; microbiome; mortality; neonatal health; neonatal outcome; neurodevelopment; new technology; offspring; peer; pregnant; recruit; retention rate; scale up; social; successful intervention

Project Summary/Abstract Building on a history of more than two decades of successful collaboration among Thomas Jefferson University (TJU), Jawaharlal Nehru Medical College (JNMC), and the NICHD Global Network for Women's and Children's Health Research, we seek to ensure the continued growth, development, and sustainability of our partnership via the next cycle of the Global Network (GN). Specific project aims include: • Provide experienced leadership within the GN fostering innovation, research excellence, and conduct of common protocols addressing major causes of maternal/child morbidity/mortality in LMICs, and incorporating implementation research aiming to scale up successful interventions and influence public health policy; • Identify and address gaps in maternal and child health research, utilizing a team-based approach to design, develop, implement, and evaluate promising health interventions, focusing on those addressing public health crises that impact the health of pregnant/lactating women and their offspring, and promoting progress toward achievement of the NICHD Strategic Plan 2020 and the 2030 Sustainable Development Goals for maternal, newborn, and under-5 mortality, and, as appropriate, health financing, and workforce development; • Engage local stakeholders by continuing to involve the Ministries of Health at the local, state, and national level; incorporating ASHA workers and auxiliary nurses into the research team (with approval of the MOH); and establishing a local Community Engagement Board comprising lay community members to provide local perspective on research outcomes of most benefit to participants, support dissemination of research findings, and promote translation of research evidence into practice; • Expand research capacity and catchment areas within Karnataka, as well as to other states in India – specifically Maharashtra, Rajasthan, and Odisha – resulting in greater generalizability of findings to all regions and populations of the country and other low resource settings globally; • Conduct GN approved common protocols with high recruitment and retention rates encompassing a range of study designs (e.g., RCTs, formative, translational, mixed methods, observational, and implementation research) initiated by GN investigators, as well as those proposed by outside investigators; • Apply the guiding principles of NICHD-supported multi-site clinical research which are: 1) Enhance rigor and reproducibility, 2) Promote greater availability of multisite clinical trial infrastructure to support trials from a wider range of investigators, 3) Facilitate data sharing and access to biospecimens, 4) Facilitate greater involvement of diverse populations in multisite clinical trials; • Disseminate research findings with the goal of influencing health policy and system changes and to scale up evidence-based interventions to promote meaningful and sustainable health improvements.

项目概要/摘要 建立在托马斯杰斐逊大学二十多年成功合作历史的基础上 (TJU)、贾瓦哈拉尔尼赫鲁医学院 (JNMC) 和 NICHD 全球妇女儿童网络 健康研究，我们力求确保我们的合作伙伴关系持续增长、发展和可持续性 通过全球网络 (GN) 的下一个周期，具体项目目标包括： • 在 GN 内提供经验丰富的领导力，促进创新、卓越研究和行为 解决中低收入国家孕产妇/儿童发病/死亡主要原因的共同方案，并纳入 旨在扩大成功干预措施并影响公共卫生政策的实施研究； • 确定并弥补孕产妇和儿童健康研究方面的差距，利用基于团队的方法 设计、开发、实施和评估有前景的健康干预措施，重点关注针对公众的干预措施 影响孕妇/哺乳期妇女及其后代健康并促进进步的健康危机 实现 NICHD 2020 年战略计划和 2030 年可持续发展目标 孕产妇、新生儿和 5 岁以下儿童死亡率，以及酌情卫生筹资和劳动力发展； • 通过继续让地方、州和国家卫生部参与进来，让当地利益相关者参与进来。 将 ASHA 工作人员和辅助护士纳入研究团队（经卫生部批准）； 建立一个由非专业社区成员组成的当地社区参与委员会，以提供当地 对参与者最有利的研究成果的看法，支持研究成果的传播， 促进研究证据转化为实践； • 扩大卡纳塔克邦以及印度其他邦的研究能力和服务范围 – 特别是马哈拉施特拉邦、拉贾斯坦邦和奥里萨邦——使研究结果具有更大的普适性，适用于所有地区 以及该国和全球其他资源匮乏地区的人口； • 执行 GN 批准的通用协议，具有高招募率​​和保留率，包括 研究设计的范围（例如随机对照试验、形成性、转化性、混合方法、观察性和 实施研究）由 GN 研究人员发起，以及外部研究人员提出的研究； • 应用 NICHD 支持的多中心临床研究的指导原则，这些原则是： 1) 增强严谨性 和可重复性，2) 提高多地点临床试验基础设施的可用性，以支持来自多个地点的试验 更广泛的研究人员，3) 促进数据共享和生物样本的获取，4) 促进更多 不同人群参与多中心临床试验； • 传播研究成果，以影响卫生政策和系统变革并扩大规模 加强基于证据的干预措施，以促进有意义和可持续的健康改善。

项目成果

Neonatal deaths in rural Karnataka, India 2014-2018: a prospective population-based observational study in a low-resource setting.

• DOI: 10.1186/s12978-020-01014-6
• 发表时间: 2020-11-30
• 期刊: Reproductive health
• 影响因子: 3.4
• 作者: Dhaded SM;Somannavar MS;Moore JL;McClure EM;Vernekar SS;Yogeshkumar S;Kavi A;Ramadurg UY;Nolen TL;Goldenberg RL;Derman RJ;Goudar SS
• 通讯作者: Goudar SS

Prediction and Prevention of Spontaneous Preterm Birth: ACOG Practice Bulletin, Number 234.

• DOI: 10.1097/aog.0000000000004612
• 发表时间: 2021-12-01
• 期刊: Obstetrics and gynecology
• 影响因子: 7.2
• 作者: Hoffman MK

Global Maternal and Child Health:: A Research Partnership's Approach for Addressing Challenges and Reducing Health Disparities in Developing Countries.

全球妇幼健康：研究伙伴关系应对发展中国家挑战和减少健康差距的方法。

• DOI: 10.32481/djph.2018.07.002
• 发表时间: 2018
• 期刊: Delaware journal of public health
• 作者: Derman,RichardJ;Goudar,ShivaprasadS;Jaeger,FrancesJ;Khan,Omar
• 通讯作者: Khan,Omar

Hemoglobin concentrations and adverse birth outcomes in South Asian pregnant women: findings from a prospective Maternal and Neonatal Health Registry.

• DOI: 10.1186/s12978-020-01006-6
• 发表时间: 2020-11-30
• 期刊: Reproductive health
• 影响因子: 3.4
• 作者: Ali SA;Tikmani SS;Saleem S;Patel AB;Hibberd PL;Goudar SS;Dhaded S;Derman RJ;Moore JL;McClure EM;Goldenberg RL
• 通讯作者: Goldenberg RL