UIC-JNMC Women's & Children's Research Unit

UIC-JNMC 女子

• 批准号: 7001056
• 负责人: RICHARD J DERMAN
• 金额: $ 6.17万
• 依托单位: UNIVERSITY OF MISSOURI KANSAS CITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-23 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7001056
• 关键词: India; cooperative study; culture; disease /disorder proneness /risk; female; health behavior; health science research analysis /evaluation; hemorrhage; hormone therapy; human morbidity; human mortality; human subject; human therapy evaluation; medical complication; outcomes research; patient oriented research; postpartum; prostaglandin E; prostaglandin analogs; public health; questionnaires; socioeconomics; women' s health

The Division of Women's Health (Department of Obstetrics and Gynecology) in conjunction with the Division of Neonatology (Department of Pediatrics), College of Medicine, University of Illinois at Chicago (IJIC) are applying for a Global Network for Women's and Children's Health Research Unit. Together with our international partner, Jawaharlal Nehru Medical College located in Belgaum, Karnataka, India, we propose: 1) to expand and strengthen the existing research infrastructure in India and to increase public health capabilities in the area of maternal and child health, 2) to build on the collaborative relationship existing between JN Medical College and UIC and to provide opportunities for collaborative research that focuses on leading causes of morbidity and mortality in pregnancy and early childhood. Consistent with an objective for establishing Global Network Research Units, we have a commitment to designing, implementing, and evaluating evidence-based interventions and supporting our international partner, JNMC, in carrying out basic biomedical and behavioral research, clinical and translational research, and associated evaluative research that will improve health status for mothers, young children, and families in India. Out initial collaborative effort will be to conduct a prospective study directed at the problem of postpartum hemorrhage. Our study will be carried out in the Belgaum District (State of Karnataka) and test the hypothesis that the administration of misoprostol to women after delivery can reduce postpartum hemorrhage and related adverse outcomes. Additionally, we will do a case comparison of women presenting to study sites with hemorrhage and subsequently dying and women who survive postpartum hemorrhage to determine if there are differences in the two groups.

伊利诺伊大学芝加哥分校医学院妇女健康科（妇产科）与新生儿科（儿科） (IJIC) 正在申请建立全球妇女儿童健康研究中心网络。我们与我们的国际合作伙伴、位于印度卡纳塔克邦贝尔高姆的贾瓦哈拉尔尼赫鲁医学院一起建议：1) 扩大和加强印度现有的研究基础设施，并提高妇幼保健领域的公共卫生能力，2)建立在JN医学院和UIC之间现有的合作关系的基础上，并为重点关注妊娠和幼儿期发病和死亡主要原因的合作研究提供机会。与建立全球网络研究单位的目标一致，我们致力于设计、实施和评估循证干预措施，并支持我们的国际合作伙伴 JNMC 开展基础生物医学和行为研究、临床和转化研究以及相关研究。评估性研究将改善印度母亲、幼儿和家庭的健康状况。最初的合作将针对产后出血问题进行前瞻性研究。我们的研究将在贝尔高姆地区（卡纳塔克邦）进行，并测试以下假设：产后妇女服用米索前列醇可以减少产后出血和相关不良后果。此外，我们将对出现在研究地点的出血并随后死亡的女性和产后出血后幸存的女性进行病例比较，以确定两组之间是否存在差异。