Administrative Core

行政核心

• 批准号: 10747617
• 负责人: Pierre C Dagher
• 金额: $ 15.79万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10747617
• 关键词: Biological Markers; Collaborations; Communication; Communities; Disease Progression; Education; Ensure; Future; Goals; Guidelines; Indiana; Kidney; Kidney Diseases; Lead; Monitor; Pathway interactions; Research; Research Personnel; Resource Development; Resource Sharing; Resources; Services; Testing; Therapeutic Intervention; biomedical resource; imaging science; intravital microscopy; microscopic imaging; molecular imaging; outreach; preclinical study; programs; targeted treatment

Project Summary/Abstract - Administrative Core The overarching goal of the Administrative Core is to lead, manage, and harmonize all aspects of the IU O’Brien U54 National Resource Center (NRC) and ensure that that the IU O’Brien resources are shared nationally. This goal will be accomplished through collaboration with the U24 O’Brien National Coordinating Center (NCC) to: 1) Prioritize external requests from the kidney research community for the efficient utilization of the two IU O’Brien Biomedical Resource Core (BRC) resources consisting of the Intravital Microscopy BRC and the Molecular Imaging BRC; 2) engage in activities to enhance national outreach and impact of the IU O’Brien NRC; 3) educate the community about kidney research; 4) monitor and evaluate emerging advances in imaging science in conjunction with the IU O’Brien Resource Development Core; 5) asses imminent research needs of the kidney research community; 6) organize a broad range of educational programs to provide a pipeline of future kidney researchers, assist early stage investigators, and attract new investigators from outside the kidney research community; and 7) develop pathways that enhance the diversity of the kidney research community. The Administrative Core will serve as the portal for communication and coordination with the O’Brien U24 NCC, other U54 O’Brien NRCs in the consortium, and the kidney research community at large. The IU O’Brien Resource Center will provide a unique and powerful service to the kidney research community. Together, the assets of the two IU O’Brien BRCs and the Resource Development Core coordinated by the Administrative Core will allow investigators in the kidney research community to test and refine key hypotheses as they pertain to a vast array of kidney diseases. Therefore, the proposed research service is significant, because it is expected to aid the kidney research community in identifying critically needed biomarkers of disease progression, optimizing preclinical studies, and developing specific and targeted therapeutic interventions for a wide range of kidney diseases.

项目摘要/摘要 - 管理核心 行政核心的总体目标是领导，管理和协调 IU O'Brien U54国家资源中心（NRC），并确保IU O'Brien资源是 在全国范围内。 协调中心（NCC）至：1）优先考虑肾脏研究社区的外部请求 两个IU O'Brien生物医学资源核心核心核心核心核心核心核心核心核心（BRC）的有效利用 显微镜BRC和分子成像BRC； IU O'Brien NRC的影响； 3）教育社区有关肾脏研究； 与IU -Brien Resource Development Core的成像科学的新兴进步； 肾脏研究界的迫在眉睫的研究需求； 6） 提供提供未来肾脏研究人员的管道，协助早期研究人员的计划，并吸引新的 来自肾脏研究社区外的研究人员； 在肾脏研究界 与O'Brien U24 NCC协调，联盟中的其他U54 O'Brien NRC和肾脏研究 整个社区。 研究社区。 由行政核心协调将允许肾脏研究界的调查人员进行测试和 优化主要的假设，因为它们与各种肾脏疾病有关 服务很重要，期望人能帮助肾脏研究社区确定批判性 需要疾病的生物标志物，专业的临床前研究，并开发特定的和有针对性的 各种肾脏疾病的治疗干预措施。