Research Project 1

研究项目1

基本信息

批准号：
10738712
负责人：
Martin Lajous
金额：
$ 39.96万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-20 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10738712
关键词：
Address Adoption Adult Age Breast Cancer Detection Cancer Control Cancer Etiology Caring Cellular Phone Cervical Cancer Screening Colonoscopy Colorectal Cancer Country Development Diagnostic Dissemination and Implementation Early Diagnosis Effectiveness Electronic Health Record Evidence based intervention Family Feedback Funding Gastroenterologist Goals Health Personnel Health system Healthcare Healthcare Systems Hybrids Incidence Institution Integrated Health Care Systems Interruption Intervention Interview Knowledge Link Local Government Malignant Neoplasms Maps Measures Medical Care Team Methods Mexican Mexico Modeling Morbidity - disease rate Patient Education Patients Population Process Public Health Records Research Research Project Grants Resource-limited setting Resources Risk Scientific Advances and Accomplishments Screening for cancer Series Specialist Standardization Telephone Testing Texas Text Messaging Time Training Woman arm colorectal cancer screening cost cost effective cost effectiveness design economic cost economic evaluation effectiveness evaluation effectiveness outcome effectiveness/implementation study evidence base implementation design implementation facilitators implementation outcomes implementation research implementation science implementation strategy improved incremental cost member men microcosting mortality organizational readiness patient navigation patient screening primary care clinician programs prospective relative cost research study retiree screening screening guidelines screening program testing uptake virtual

项目摘要

PROJECT SUMMARY Colorectal cancer (CRC) is exerting a significant public health impact in Mexico despite the availability of effective screening strategies. Yet, there are no national CRC screening (CRCS) guidelines or organized CRCS programs in Mexico. We aim to implement a CRCS program in an integrated health system that is context- appropriate, sustainable, scalable, and easily transferable to different health systems in Mexico. We will optimize FIT uptake and CRCS completion by adapting and evaluating evidence-based interventions (EBIs) (patient education, patient reminders, patient navigation); designing implementation strategies (training with technical assistance, practice champions, audit and feedback) to deliver these EBIs; and evaluating the effectiveness, cost-effectiveness, and implementation outcomes using a type 2 hybrid effectiveness implementation study. Our proposed research is potentially groundbreaking and of substantial public health significance in that it will be the first implementation research study in Mexico to address CRCS while applying rigorous implementation science methods. It will advance scientific knowledge on the effectiveness of EBIs that have been developed and tested in other countries and adapted for use in Mexico; it will also study the impact of implementation strategies to deliver them in a real-world setting. Our proposed study will incorporate an economic evaluation of the implementation of the EBIs to provide healthcare institutions with the necessary information to plan for adoption and sustainability in settings with different resources.

项目概要尽管有可用的治疗方法，但结直肠癌 (CRC) 正在对墨西哥的公共健康产生重大影响有效的筛查策略。然而，尚无国家 CRC 筛查 (CRCS) 指南或有组织的 CRCS 墨西哥的计划。我们的目标是在综合卫生系统中实施 CRCS 计划，该系统是适当、可持续、可扩展且易于转移到墨西哥的不同卫生系统。我们将通过调整和评估循证干预措施 (EBI) 来优化 FIT 的吸收和 CRCS 的完成（患者教育、患者提醒、患者导航）；设计实施策略（培训技术援助、实践倡导者、审计和反馈）来交付这些 EBI；并评估使用 2 类混合有效性的有效性、成本效益和实施结果实施研究。我们提出的研究具有潜在的突破性并且对公共卫生具有重大意义意义在于，这将是墨西哥第一个在应用中解决 CRCS 问题的实施研究严格执行科学方法。它将推进有关 EBI 有效性的科学知识，已在其他国家开发和测试并适用于墨西哥；它还将研究影响在现实环境中交付它们的实施策略。我们提出的研究将包括对 EBI 实施情况进行经济评估，为医疗机构提供必要的支持用于规划具有不同资源的环境中的采用和可持续性的信息。