Cancer Prevention and Control Research Program

癌症预防与控制研究计划

基本信息

批准号：
10628433
负责人：
Victoria Jane Findlay
金额：
$ 4.09万
依托单位：
VIRGINIA COMMONWEALTH UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1995
资助国家：
美国
起止时间：
1995-12-01 至 2028-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10628433
关键词：
Address Advanced Malignant Neoplasm African American African American population Automobile Driving Award Behavior Behavioral Biological Black Populations Black race Breast Cancer Burden Cancer Center Cancer Center Support Grant Cancer Control Cancer Control Research Cancer Control Research Program Cancer Patient Cancer health equity Caregivers Catchment Area Charge Clinic Clinical Collaborations Communities Community Clinical Oncology Program Community Health Community Outreach Continuity of Patient Care Diagnosis Discipline Disease Disparity Doctor of Philosophy Early Diagnosis Enrollment Ensure Equity Ethnic Origin Fostering Funding Funding Opportunities Goals Health Promotion Historically Black Colleges and Universities Hot Spot Humanities Individual Inequity International Intervention Intervention Studies Intervention Trial Investments Lead Leadership Life Style Long-Term Survivors Lung Malignant Neoplasms Malignant neoplasm of gastrointestinal tract Malignant neoplasm of lung Malignant neoplasm of prostate Massey Cancer Center at the Virginia Commonwealth University Medical Methods Minority Minority Groups Mission National Cancer Institute National Institute of Drug Abuse Nature Operative Surgical Procedures Outcome Patients Peer Review Pharmacy facility Policies Population Heterogeneity Prevalence Prevention Preventive Principal Investigator Prostate Psychiatry Publications Quality of life Race Records Reporting Research Research Personnel Resource Sharing Resources Risk Factors Rural Science Scientist South Carolina Specialized Program of Research Excellence Strategic Planning Supportive care Symptoms Testing Tobacco Training Programs United States National Institutes of Health Universities Urban Community Virginia anticancer research cancer care cancer health disparity cancer prevention cancer risk cancer type college community center community engaged research community engagement comorbidity disparity reduction early screening effectiveness testing gastrointestinal geographic disparity health equity improved inter-institutional intersectionality intervention participants lung cancer screening malignant breast neoplasm medical schools meetings member mid-career faculty mortality multidisciplinary multimodality obesity prevention population health professor programs racial disparity recruit risk mitigation screening disparities social survivorship symposium tobacco control tobacco products translational engagement

项目摘要

CANCER PREVENTION AND CONTROL PROGRAM: PROJECT SUMMARY The Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) first introduced its Cancer Prevention and Control (CPC) Program within the Cancer Center Support Grant (CCSG) in 1991. The CPC Program has matured into a highly multidisciplinary nexus of investigators, including population health as well as clinical and basic scientists, and the program continues its emphasis on identifying and mitigating cancer risks. However, since the last CCSG renewal, the CPC Program has recruited multiple new experts in survivorship research, further expanding its impact across the cancer care continuum. The Program is highly focused on addressing MCC’s and the community’s priority disease concerns – lung, gastrointestinal, breast, and prostate cancers – as well as two lifestyles or behaviors significantly driving the cancer burden (tobacco control and obesity prevention). CPC research aligns well with the MCC’s Community-to-Bench framework and its mission, goals, and strategic plans, and the program leads Center efforts actively engaging the community in research. Furthermore, the Center-wide emphasis on reducing disparities is exemplified by many CPC members’ efforts to understand and address inequities among racial/ethnic as well as rural/urban communities, and notably where the two intersect. For instance, within MCC’s catchment area, it is the rural Virginia communities with majority-minority populations of Blacks/African Americans being reported among the nation’s cancer hot spots. Led by Oxana G. Palesh, PhD and Victoria J. Findley PhD, the CPC Program comprises 44 scientists representing 12 departments across the Schools of Medicine, Pharmacy, and the College of Humanities and Science. The program has $6.8M in annual, direct, peer-reviewed funding ($2.5M from NCI, $3.1M from other NIH institutes; and $1.2 from other agencies). In the current project period, CPC members authored 337 cancer- focused research publications reflecting the highly collaborative nature of these scientists; 125 (37%) were intra- programmatic, 46 (14%) were inter-programmatic, 233 (69%) were inter-institutional with 161 (48%) being collaborations with other NCI-designated cancer centers. In addition, the CPC Program has tripled the number of multi-Principal Investigator (MPI) and multi-project awards during the current project period. Their portfolio now includes 16 MPI R01/R21s, two U01s, one UG1, one U54, two P20s, and a Stand Up to Cancer award. The CPC Program also has a growing portfolio of clinic- and community-based interventional studies addressing disparities, supportive care needs, and survivorship, and investigators and since 2016 have enrolled 1,663 individuals to interventional studies and over 18,000 to non-interventional studies. During the next CCSG project period, the CPC Program will continue to anchor its efforts around community-based and community-engaged research to identify and decrease cancer risks, increase cancer screening, and reduce disparate cancer outcomes and inequities for all patients.

癌症预防和控制计划：项目摘要弗吉尼亚联邦大学 (VCU) 梅西癌症中心 (MCC) 首先介绍了其癌症 1991 年癌症中心支持补助金 (CCSG) 内的预防和控制 (CPC) 计划。CPC 该计划已发展成为一个高度多学科的研究人员联盟，其中也包括人口健康作为临床和基础科学家，该计划继续强调识别和减轻癌症然而，自上次 CCSG 更新以来，CPC 计划已招募了多名新专家。生存研究，进一步扩大其在整个癌症护理连续体中的影响。专注于解决 MCC 和社区的优先疾病问题——肺部、胃肠道、乳腺癌、和前列腺癌——以及两种显着增加癌症负担的生活方式或行为（烟草 CPC 研究与 MCC 的 Community-to-Bench 框架非常吻合，并且它的使命、目标和战略计划，以及该计划领导中心的努力，积极让社区参与此外，中央对缩小差距的重视体现在许多共产党员的努力理解和解决种族/族裔以及农村/城市社区之间的不平等，值得注意的是例如，在 MCC 的服务范围内，是弗吉尼亚州的农村社区。据报道，黑人/非裔美国人占多数的少数族裔是该国的癌症热点地区。 CPC 项目由 Oxana G. Palesh 博士和 Victoria J. Findley 博士领导，由 44 名科学家组成代表医学院、药学院和人文学院的 12 个系该项目每年获得 680 万美元的直接同行评审资金（250 万美元来自 NCI，310 万美元来自其他机构） NIH 机构；以及其他机构的 1.2 美元）在当前项目期间，CPC 成员撰写了 337 篇癌症文章。反映这些科学家高度协作性质的重点研究出版物；125 名（37%）是内部科学家项目间，46 个 (14%) 是项目间项目，233 个 (69%) 是机构间项目，其中 161 个 (48%) 是项目间项目与其他 NCI 指定癌症中心的合作此外，CPC 项目的数量增加了两倍。当前项目期间的多首席研究员（MPI）和多项目奖项。现在包括 16 个 MPI R01/R21、2 个 U01、1 个 UG1、1 个 U54、2 个 P20 和一个“抗击癌症”奖。 CPC 计划还拥有越来越多的临床和社区干预研究组合，解决以下问题：自 2016 年以来，已招募了 1,663 名研究人员在下一个 CCSG 项目期间，将有 18,000 个人参与干预性研究，并有超过 18,000 人参与非干预性研究。在此期间，CPC 计划将继续围绕社区为本和社区参与开展工作识别和降低癌症风险、加强癌症筛查并减少不同癌症的研究所有患者的结果和不平等。