Biology Core

生物核心

基本信息

批准号：
7718040
负责人：
Eric A. Whitsel
金额：
$ 297.01万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-01-01 至 2010-12-31
项目状态：
已结题

项目摘要

In Year 13, the Biology Core will work closely with the Data Collection subproject and Dissemination Core to monitor all aspects of main study biological data collection and the resulting specimen archive. The Biology Core will have primary responsibility for monitoring the quality and reliability of biological specimens and data, including anthropometric measurements, medication inventory data, and assay results. The Core will also oversee systems for the tracking, storage and archiving of biological samples. By reviewing data distributions and value ranges, the Biology Core will assist the Dissemination Core in data cleaning and dissemination. The Biology Core will also provide documentation of data collection protocols, specimen collection and biological measures to the Dissemination Core for distribution to data users. To ensure that the science produced with the biological data from Add Health is consistent with the scientific goals of our project, the Biology Core will continue to evaluate proposals by researchers seeking to use archived biological specimens. Reviews will be submitted to the Project Director, who, in collaboration with the Deputy Director and Biology Core Pis, will decide whether to grant and/or recommend changes in the researcher's request. Throughout Year 13, the Biology core will continue to provide scientific guidance and advice for the integration of biological paradigms and data into subproject theoretical models and analysis plans. Scientific guidance and advice will occur through mutual work and collaboration among Biology Core members and Program Investigators. The Biology Core will also assist in the preparation of research methods papers based on the results of the cortisol and incentive experiments embedded in the Wave IV pretest.

在第 13 年，生物学核心将与数据收集子项目和传播核心密切合作，以监控主要研究生物数据收集的各个方面以及由此产生的标本存档。生物学核心将主要负责监测生物样本和数据的质量和可靠性，包括人体测量、药物库存数据和化验结果。核心还将监督生物样本的跟踪、存储和归档系统。通过审查数据分布和数值范围，生物学核心将协助传播核心进行数据处理清洁和传播。生物学核心还将提供数据收集协议的文档，样本采集和生物测量到传播核心以分发给数据用户。确保使用 Add Health 的生物数据得出的科学结果与科学依据一致为了实现我们项目的目标，生物学核心将继续评估研究人员寻求使用的提案存档的生物标本。审查将提交给项目总监，项目总监将与副主任兼生物学核心 Pis，将决定是否批准和/或建议更改研究员的要求。在整个 13 年，生物学核心将继续为整合提供科学指导和建议将生物学范式和数据转化为子项目理论模型和分析计划。科学指导并通过生物学核心成员和计划之间的共同工作和协作提供建议调查人员。生物学核心还将协助准备基于 Wave IV 预测试中嵌入的皮质醇和激励实验的结果。