Obesity Research Center Training Grant

肥胖研究中心培训补助金

基本信息

批准号：
10621280
负责人：
DYMPNA GALLAGHER
金额：
$ 15.69万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
1989
资助国家：
美国
起止时间：
1989-07-01 至 2027-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10621280
关键词：
Grant Obesity Research Training

项目摘要

Project Summary/Abstract This T32 post-doctoral training program, now in its 31st year, provides 2-3 years of fellowship designed to prepare PhDs and physicians for investigative careers in obesity research. Of the fellows trained with support from this T32 during the past 15 years, 92% remain in research (academic, industry) positions related to obesity and allied disorders. Our Specific Aim is to train promising young scientists to become independent investigators focusing on obesity-related issues. Our long-term objective is to increase the investigator pool working on the broad biology of obesity and its co-morbidities. This program has important national implications since obesity is among the foremost health problems facing America, imposing growing costs in terms of human suffering, health care and productivity. There is a critical dearth of well-trained young investigators. We provide a structured curriculum in the first 2 years (includes career development and grantsmanship), in combination with a research experience emphasizing wide opportunities in basic laboratory and/or translational research, reflecting the great strengths of Columbia University in these areas. Post-doctoral fellows are appointed at Columbia University, enabling access to a wide array of formal courses throughout the University. The T32 has specified course requirements that are attuned to the fellow’s previous experience and selected research project. Fellows participate in seminars of obesity, diabetes, nutrition and other bioscience Centers of the University. Trainees elect to work with a faculty member at Columbia and are incorporated into the investigative program of mentors at the New York Nutrition Obesity Research Center and other laboratories. The faculty's multidisciplinary nature (physicians, biochemists, cell biologists, pathologists, neuroscientists, psychiatrists, nutritionists, molecular biologists and geneticists) allows a multi-disciplinary approach by the trainees. Strong collaborative ties among the training faculty make this possible. Trainees have access to the entire spectrum of research tools in obesity biology, ranging from structural/cell biology, molecular genetics and neuroscience through clinical investigation. Trainees are (1) physicians who have completed 3 to 5 years of post-graduate clinical training, (2) recent PhD (or equivalent) recipients in disciplines including (but not limited) to molecular genetics, biochemistry, nutrition, physiology, neuroendocrinology, neuroscience, or pharmacology. Individuals are selected based on their demonstrated competence in medical and/or graduate school, recommendations of their faculties, and consideration of the extent to which their research interests are congruent with those of the Columbia faculty. All trainees at time of entry must be pursuing an investigative career in obesity (including its complications) or appetitive behaviors. An Individual Development Plan is created for each trainee and is monitored by an ad hoc Scholarly Oversight Committee. Minority diversity is an explicit goal of the program. Each of the participating faculty laboratories (n= 25: 7 Junior/18 Senior) is well equipped and funded to support a trainee's research. Continued funding for 3 trainee slots per year for a 5-year award is requested.

项目概要/摘要 T32 博士后培训项目现已进入第 31 个年头，提供 2-3 年的奖学金，旨在为在肥胖研究领域接受培训的博士和医生。 T32 在过去 15 年中，92% 仍担任与肥胖及相关相关的研究（学术、工业）职位我们的具体目标是培养有前途的年轻科学家成为独立的重点研究人员。我们的长期目标是增加从事广泛研究的研究人员队伍。肥胖及其并发症的生物学研究由于肥胖是其中之一，因此该计划具有重要的全国意义。美国面临的最重要的健康问题，在人类痛苦、医疗保健方面造成的成本不断增加我们提供了结构化的课程，培养了训练有素的年轻研究人员。在前两年（包括职业发展和资助），结合研究经验强调基础实验室和/或转化研究的广泛机会，反映巨大的优势哥伦比亚大学在这些领域任命了博士后研究员，从而使之成为可能。访问整个大学的各种正式课程 T32 有指定的课程要求。与研究员之前的经验和选定的研究项目相适应。肥胖、糖尿病、营养等大学生物科学中心的研讨会学员选择工作。与哥伦比亚大学的一名教员一起，并被纳入新大学导师的调查计划约克营养肥胖研究中心和其他实验室的师资队伍具有多学科性质（医生、生物化学家、细胞生物学家、病理学家、神经科学家、精神病学家、营养学家、分子生物学家和遗传学家）允许学员在培训中采用多学科方法。教师使这成为可能，学员可以使用肥胖生物学的全部研究工具，范围从结构/细胞生物学、分子遗传学和神经科学到临床研究。是 (1) 已完成 3 至 5 年研究生临床培训的医生，(2) 最近获得博士学位（或同等学科的接受者，包括（但不限于）分子遗传学、生物化学、营养学、根据生理学、神经内分泌学、神经科学或药理学选择个人。医学和/或研究生院的能力，其院系的证明推荐，以及考虑他们的研究兴趣与哥伦比亚大学教师的研究兴趣的一致程度。学员在入学时必须从事肥胖症（包括其并发症）的研究工作，或者为每位学员制定个人发展计划，并由专人监督。学术监督委员会是每个参与项目的明确目标。教师实验室（n= 25：7名初级/18名高级）设备齐全，资金充足，可以支持学员的研究。要求每年继续为 3 个实习生名额提供资助，以获得为期 5 年的奖励。

项目成果

期刊论文数量（74）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Sleep disturbances, body fat distribution, food intake and/or energy expenditure: pathophysiological aspects.

DOI：
10.1515/hmbci-2013-0066
发表时间：
2014-01
期刊：
Hormone molecular biology and clinical investigation
影响因子：
1
作者：
St-Onge MP;Shechter A
通讯作者：
Shechter A

Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery.

西他列汀对 Roux-en-Y 胃绕道手术后 2 型糖尿病患者血糖控制的影响。

DOI：
10.1111/dom.13139
发表时间：
2018
期刊：
Diabetes, obesity & metabolism
影响因子：
0
作者：
Shah,Ankit;Levesque,Kiarra;Pierini,Esmeralda;Rojas,Betsy;Ahlers,Michael;Stano,Sarah;Holter,Marlena;Dutia,Roxanne;Belsley,Scott;McGinty,James;Laferrère,Blandine
通讯作者：
Laferrère,Blandine

HIV infection and increased food insecurity are associated with adverse body composition changes among pregnant and lactating Kenyan women.

艾滋病毒感染和粮食不安全加剧与怀孕和哺乳期肯尼亚妇女身体成分的不良变化有关。

DOI：
10.1038/s41430-018-0285-9
发表时间：
2019
期刊：
European journal of clinical nutrition
影响因子：
4.7
作者：
Widen,ElizabethM;Tsai,Irene;Collins,ShaleanM;Wekesa,Pauline;China,Joy;Krumdieck,Natalie;Miller,JoshuaD;Weiser,SheriD;Onono,Maricianah;Young,SeraL
通讯作者：
Young,SeraL

Sleep Restriction in Adolescents: Forging the Path Towards Obesity and Diabetes?