Cancer Epidemiology

癌症流行病学

• 批准号: 8340084
• 负责人: George J. Weiner
• 金额: $ 5.28万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-19 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340084
• 关键词: Achievement; Agriculture; Animal Testing; Appointment; Area; Basic Science; Behavior; Biological Assay; Cancer Burden; Cancer Center Support Grant; Cancer Control; Cancer Etiology; Cancer Survivor; Clinic; Clinical; Diagnostic tests; Disease; Early Diagnosis; Early treatment; Environmental Exposure; Epidemiologic Studies; Epidemiology; Evaluation; Faculty; Funding; Goals; Health; Health Services; Human; Individual; Instruction; International; Knowledge; Life; Link; Malignant Neoplasms; Malignant neoplasm of lung; Measures; Outcome; Paper; Participant; Pesticides; Population; Population Sciences; Public Health; Publications; Publishing; Quality of life; Radon; Research; Research Design; Research Peer Review; Research Personnel; Risk; Risk Assessment; Risk Reduction; Rural; Screening for cancer; Services; Translations; Universities; World Health Organization; biobehavior; cancer epidemiology; cancer prevention; college; environment related cancer; epidemiologic data; improved; interest; member; neuropsychiatry; population based; prevent; professor; programs

Cancer Epidemiology Research in the Cancer Epidemiology Program focuses on the population-based study of cancer etiology, health services and outcomes, and cancer prevention and control. The overall goal of program members is to save lives by increasing our understanding of what causes cancer, promoting cancer prevention behaviors and early detection and treatment, and developing improved diagnostic tests and treatments. When cancer cannot be prevented, we are also interested in research that will extend the quantity and quality of life for the cancer survivor. There are three major overlapping themes the Program's research. The first theme involves cancer etiology. Research areas within this theme include the study of environmental exposures and cancer, other biologic causes of cancer, and evaluation of the burden of cancer. The second theme involves cancer health services & outcomes. Research areas within this theme include evaluation of the delivery of cancer services, and assessment of how biobehavior and neuropsychiatric factors impact on the burden of cancer. The third theme involves cancer prevention and control. Research areas within this theme focus on studies exploring risk reduction and cancer screening. In population science, scientific achievements can be measured by their translation into activities that improve the health of the public. In this regard, after 20 years of residential radon and lung cancer epidemiologic research here and elsewhere, the World Health Organization has been convinced and is implementing an international initiative to reduce indoor radon risks. Also the strengths of the study design and findings relating to pesticides and cancer in the Agricultural Health Study, where two-thirds of participants are lowans, has led the US EPA to announce that epidemiologic data will be used in its risk assessment of pesticides, marking a significant departure from traditional EPA practice, which has focused on short-term bioassays and animal testing in risk assessment. This highly interactive program consists of 33 members from 8 basic science and 9 clinical departments in 5 Colleges. Peer reviewed, research funding forthis program totals $6,841,168 with $2,339,558 coming from the NCI. Program members published 443 cancer-related papers over the prior funding period. Of these publications, 15% were intraprogrammatic, 18% were interprogrammatic and 7% were both intra and interprogrammatic, for a total of 39% collaborative publications.

癌症流行病学 癌症流行病学项目的研究重点是癌症病因学、卫生服务和结果以及癌症预防和控制的人群研究。计划成员的总体目标是通过增加我们对癌症病因的了解、促进癌症预防行为以及早期检测和治疗以及开发改进的诊断测试和治疗来拯救生命。当癌症 虽然无法预防，但我们也对能够延长癌症幸存者的生活数量和质量的研究感兴趣。该计划的研究有三个主要的重叠主题。第一个主题涉及癌症病因学。该主题的研究领域包括环境暴露与癌症的研究、癌症的其他生物学原因以及癌症负担的评估。第二个主题涉及癌症健康服务和结果。该主题的研究领域包括评估癌症服务的提供，以及评估生物行为和神经精神因素如何影响癌症负担。 第三个主题是癌症防治。该主题的研究领域侧重于探索降低风险和癌症筛查的研究。在人口科学中，科学成就可以通过将其转化为改善公众健康的活动来衡量。在这方面，经过 20 年在这里和其他地方进行的住宅氡气和肺癌流行病学研究，世界卫生组织 该组织已被说服并正在实施一项减少室内氡气风险的国际倡议。 此外，农业健康研究中与农药和癌症相关的研究设计和结果的优势（其中三分之二的参与者是洛万）促使美国环保局宣布流行病学数据将用于其农药风险评估，这标志着这与传统的 EPA 做法有很大不同，传统的做法侧重于风险评估中的短期生物测定和动物测试。这个高度互动的项目由来自 5 个学院的 8 个基础科学部门和 9 个临床部门的 33 名成员组成。经过同行评审，该项目的研究经费总计 6,841,168 美元，其中 2,339,558 美元来自 NCI。 项目成员在上一个资助期间发表了 443 篇癌症相关论文。在这些出版物中，15% 是计划内出版物，18% 是计划间出版物，7% 是计划内出版物和计划间出版物，总共 39% 是合作出版物。