Patient and Provider perspectives on long acting injectable ART

患者和医疗服务提供者对长效注射 ART 的看法

基本信息

批准号：
10589878
负责人：
CLARE L BARRINGTON
金额：
$ 50.16万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-05-15 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10589878
关键词：
Acquired Immunodeficiency Syndrome Adherence Adverse effects Caring Characteristics Clinic Clinical Clinical Research Communication Data Decision Making Development Disadvantaged Disclosure Dose Drug resistance Enrollment Ensure Face Fatigue Feeling Formulation Fostering Frequencies Geography Goals HIV HIV Infections HIV therapy Health Personnel Home Individual Injectable Injection Site Reaction Injections Insurance Interview Intramuscular Intramuscular Injections Investigation Medical Mental Health Oral Participant Patient Preferences Patient Selection Patients Perception Persons Pharmaceutical Preparations Phase Procedures Process Provider Quality of life Recording of previous events Regimen Reporting Research Research Design Research Methodology Resistance Respondent Risk Rural Sampling Scientist Site Stigmatization Structure Surveys System Tablets Testing Therapeutic Therapy trial Trust Viral Work antiretroviral therapy care providers clinical care clinical center cohort comorbidity demographics design drug development experience gastrointestinal individual patient informant innovation insight interest men who have sex with men pill preference prevent recruit research study residence shared decision making social social stigma substance use tool tool development uptake

项目摘要

ABSTRACT Long-acting injectable antiretroviral therapy (LAI ART) is anticipated to be a major advance in the management of HIV infection. However, how this therapeutic innovation will be received among patients and providers remains unclear. At present, there are few data with which to forecast, let alone, plan for incorporation of this innovation in HIV care into practice. Our preliminary studies demonstrate excitement for LAI ART among participants in research trials of this mode of ART administration, with possibly less enthusiasm among HIV care providers. With the proposed research studies, we seek to gain a deeper understanding of the perceptions regarding LAI ART among diverse groups of PLHIV in the US and their care providers. This understanding will be used to inform the roll-out of LAI ART, including the development of tools that PLHIV and providers can use to guide shared decision-making when choosing among treatment options.

抽象的长效注射抗逆转录病毒疗法（LAI ART）预计将成为治疗领域的重大进步 HIV 感染的管理。然而，这种治疗创新将如何被患者接受以及供应商仍不清楚。目前，可用于预测的数据很少，更不用说规划合并了将这一艾滋病毒护理创新付诸实践。我们的初步研究表明 LAI ART 令人兴奋参与这种 ART 管理模式研究试验的参与者，对艾滋病毒护理的热情可能较低提供商。通过拟议的研究，我们寻求更深入地了解人们的看法关于美国不同艾滋病病毒感染者群体及其护理人员中的 LAI ART。这种理解将用于通知 LAI ART 的推出，包括开发 PLHIV 和提供者可以使用的工具在选择治疗方案时指导共同决策。