Administrative Core

行政核心

• 批准号: 10590692
• 负责人: Oscar L. Lopez
• 金额: $ 81.28万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-15 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10590692
• 关键词: Administrator; Advisory Committees; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Animals; Area; Biological; Biological Markers; Biology; Biology of Aging; Blood; Budgets; Caregiver support; Caring; Chairperson; Clinical; Clinical Drug Development; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Complex; Critiques; DNA; Data; Data Science; Data Set; Databases; Dementia; Dementia with Lewy Bodies; Detection; Development; Developmental Process; Discipline; Disease; Education; Ensure; Epidemiology; Expenditure; Faculty; Fostering; Functional disorder; Funding; Genetic; Genetic Diseases; Geriatrics; Goals; Grant; Health Sciences; Health care facility; Image; Inflammation; Infrastructure; Inherited; International; Leadership; Ligands; Link; Maintenance; Monitor; Multicenter Studies; National Institute on Aging; Neurobiology; Neurology; Neurosciences; Pathologic; Pharmaceutical Preparations; Pharmacologic Substance; Philanthropic Fund; Physiology; Pilot Projects; Policies; Positron-Emission Tomography; Postdoctoral Fellow; Psychiatry; Recommendation; Regulation; Reproducibility; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Sampling; Schedule; Schools; Structure; Supervision; Synapses; System; Systems Biology; Technology; Testing; Tissues; Training; Training Programs; Universities; Work; aging brain; blood-based biomarker; cerebral amyloidosis; data exchange; data management; data repository; data sharing; data storage site; design; drug discovery; education research; human subject; improved; interest; interoperability; medical schools; medically underserved; meetings; minimally invasive; minority communities; multidisciplinary; neurogenetics; neuroimaging; neuropathology; novel; operation; organizational structure; outreach; peripheral blood; pre-clinical; pre-doctoral; prevent; programs; public-private partnership; recruit; repository; research study; statistics; tau Proteins; underserved community; usability

Core A: Administrative Core: Summary/Abstract: The University of Pittsburgh Alzheimer’s Disease Research Center (PITT-ADRC) Administrative (ADM) Core provides the organization and structure for planning and implementation of ADRC core and research activities. The core supervises all PITT-ADRC functions and the Clinical, Data Management & Statistics, Neuropathology, Biomarker and Neurogenetics, Neuroimaging, and Outreach, Engagement and Education Cores, as well as the Research and Education Component. The ADM Core monitors budgets to ensure fiscal responsibility; organizes the review and funding process for the Developmental Projects and for the philanthropically funded pilot studies. It monitors all PITT-ADRC research projects utilizing ADRC subjects or resources. This core determines new research directions, including the recruitment of new investigators to work in AD. Establishment of outreach efforts to the medically underserved and minority communities are directed and stimulated by the Core. The Core also oversees participation in multicenter studies, data transfer to NIA databases, tissue and DNA samples to NIA repositories, cross-ADC collaborations, and other national and international initiatives. Through the establishment of a comprehensive communications system the Core Leaders, investigators, and staff maintain an integrated, coherent and multidisciplinary focus. The goals of the ADM Core are achieved by the Executive Committee, which is comprised of the Director, Co-Director, Advisory Co-Director, Center Administrator, and Core and Project Leaders. It is aided in these tasks by advice of the Internal and External Advisory Committees, which is chaired by the Senior Vice Chancellor/Dean of the Medical School, and includes the Chairmen of Psychiatry and Neurology Departments, and the former Chair of Epidemiology at the University of Pittsburgh. They provide guidance on policy, administration, and scientific direction, as well as ensure that all schools of the Health Sciences and facilities of the University of Pittsburgh provide full cooperation in the execution of ADRC activities. The External Advisory Board is comprised of nationally respected researchers and clinicians with expertise in disciplines relevant to AD. They provide scientific critiques of research and operations of the PITT-ADRC, as well as recommendations for new initiatives. The ADM Core coordinates a well-established research infrastructure that will serve to the local, national, and international scientific community. We anticipate that the ADM Core will continue improving the ADRC data distribution. We have an exemplary record of data sharing and collaboration.

核心 A： 行政核心： 摘要/摘要： 匹兹堡大学阿尔茨海默病 研究中心 (PITT-ADRC) 行政 (ADM) 核心提供规划的组织和结构 ADRC 核心和研究活动的实施和实施 该核心监督所有 PITT-ADRC 职能和工作。 临床、数据管理和统计、神经病理学、生物标志物和神经遗传学、神经影像学、 外展、参与和教育核心，以及研究和教育部分。 ADM 核心监控预算以确保财务责任；组织审查和资助流程； 发展项目和慈善资助的试点研究 它监控所有 PITT-ADRC 研究。 利用 ADRC 主题或资源的项目 该核心确定了新的研究方向，包括 招募新的调查员在 AD 领域工作 为医疗服务不足的人群开展外展工作。 核心也监督参与。 多中心研究、数据传输至 NIA 数据库、组织和 DNA 样本至 NIA 存储库、跨 ADC 通过建立全面的合作以及其他国家和国际举措。 核心领导、调查人员和工作人员保持一个完整、连贯和一致的沟通系统 多学科焦点。 ADM 核心的目标由执行委员会实现，该委员会由董事、 联合主任、咨询联合主任、中心管理员以及核心和项目负责人在这些方面得到协助。 根据内部和外部咨询委员会的建议执行任务，该委员会由高级副总裁担任主席 医学院院长/院长，包括精神病学和神经病学系的主席， 和匹兹堡大学流行病学前任主席他们提供政策指导， 管理和科学指导，并确保所有健康科学学校和设施 匹兹堡大学在 ADRC 活动的执行中提供全面合作。 董事会由在国家学科领域受人尊敬的研究人员和教师组成，他们具有相关专业知识 AD。他们对 PITT-ADRC 的研究和运作以及 新举措的建议。 ADM 核心协调完善的研究基础设施，为地方、国家、 我们预计 ADM 核心将继续改进 ADRC。 我们在数据共享和协作方面拥有堪称典范的记录。