Tennessee Center for AIDS Research (TN-CFAR)

田纳西州艾滋病研究中心 (TN-CFAR)

• 批准号: 10617275
• 负责人: John Koethe
• 金额: $ 209.58万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617275
• 关键词: Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Affect; African American population; Area; Collaborations; Communities; Data; Development; Disease Outbreaks; Doctor of Philosophy; Environment; Epidemic; Extramural Activities; Fostering; Funding; Goals; HIV; HIV Infections; HIV Seronegativity; HIV/AIDS; Health; Health Sciences; Institution; Knowledge; Laws; Leadership; Medical; Minority Groups; Mission; Needle-Exchange Programs; Persons; Populations at Risk; Postdoctoral Fellow; Public Policy; Research; Research Personnel; Resources; Rural; Science; Scientist; Southeastern United States; Tennessee; Underserved Population; United States; United States National Institutes of Health; Vision; Work; career development; community engaged research; community engagement; community organizations; community partnership; dashboard; design; experience; falls; high risk; implementation science; improved; medical schools; multidisciplinary; next generation; novel; prevent; success; surveillance data; synergism; tool; translational impact; working group

Overall – PROJECT SUMMARY Decades of research have generated knowledge and tools with the potential to prevent all new HIV infections, to ultimately end the HIV epidemic in the United States and worldwide, and to improve the lives of people living with HIV. To date, reality has fallen short of these goals, in part due to pressing unmet needs. The Tennessee Center for AIDS Research (CFAR) is located in the Southeastern United States, the region with the greatest number of new HIV infections, and of persons living with HIV. This CFAR was established in 2015, under the leadership of Prof. Simon Mallal, as a three-way partnership between a research-intensive medical institution (Vanderbilt University Medical Center, VUMC), a historically black medical college (Meharry Medical College, MMC), and an academically engaged state health department (Tennessee Department of Health, TDH). This partnership has fostered collaborations that would be unimaginable without CFAR. For example, results of an analysis by VUMC and MMC investigators using TDH surveillance data has affected statewide public policy and law regarding needle exchange, reducing the likelihood of a potentially devastating HIV outbreak in rural Tennessee. To end the epidemic, it is becoming increasingly important to pursue community-engaged research, to include both people living with HIV and those at high risk. Toward this end, this CFAR has newly partnered with a fourth institution, Nashville CARES, a sophisticated community-based organization with a 25-year exclusive focus on people living with HIV and those at high risk. Through this four-way partnership, our vision is to have transformative, local and global translational impact. Guided by this vision, our mission is to coordinate the complementary institutional and community strengths and resources of VUMC, MMC, TDH and CARES to most effectively reduce the burden of HIV/AIDS and generalize these benefits nationally and globally. Work of this CFAR aligns with National Institutes of Health high priorities for NIH/AIDS research. To fulfill our mission, this CFAR will pursue four specific aims: 1) To support multidisciplinary HIV research that leverages the highly collaborative local environment to build impactful team science among the four institutions of the CFAR; 2) To nurture and support career development of junior investigators, so as to grow the number and diversity of the next generation of HIV researchers; 3) To specifically enable HIV research opportunities for MMC investigators, to include engagement with investigators and resources across the CFAR, and leveraging team science; and 4) To continue to grow a broad emphasis on HIV-focused community-engaged research that pervades the CFAR, and with a focus on ending the epidemic.

总体 - 项目摘要 数十年的研究产生了知识和工具，有可能防止所有新的艾滋病毒感染， 最终结束了美国和全球的艾滋病毒流行，并改善生活的人们的生活 与艾滋病毒。迄今为止，现实未达到这些目标，部分原因是迫切需要未满足的需求。田纳西州 艾滋病研究中心（CFAR）位于美国东南部，该地区最大 新的艾滋病毒感染和艾滋病毒感染者的数量。该CFAR成立于2015年，根据 西蒙·马拉尔（Simon Mallal）教授的领导，作为研究密集型医疗机构之间的三向伙伴关系 （VUMC范德比尔特大学医学中心），一所历史悠久的黑人医学院（Meharry医学院， MMC）和一个学术参与的州卫生部（田纳西州卫生局，TDH）。这 合作伙伴关系促进了没有CFAR的合作，这将是无法想象的。例如， VUMC和MMC调查人员使用TDH监视数据进行了分析，影响了全州范围的公共政策和 有关针头交换的法律，减少了农村中潜在毁灭性艾滋病毒爆发的可能性 田纳西州。为了结束流行病，购买社区参与研究的越来越重要， 包括艾滋病毒感染者和高风险的人。为此，此CFAR已新合作 纳什维尔（Nashville）拥有第四个机构，是一个成熟的社区组织，拥有25年 专注于艾滋病毒和高风险的人。通过这种四向伙伴关系，我们的愿景是 具有变革性，本地和全球翻译影响。在这个愿景的指导下，我们的使命是协调 VUMC，MMC，TDH的互补机构和社区优势和资源都在乎 最有效地减少了艾滋病毒/艾滋病的伯恩（Burnen），并在全国和全球范围内概括这些好处。工作 该CFAR与美国国立卫生研究院（NIH/AIDS）研究的高度优先事项保持一致。履行我们的使命， 该CFAR将追求四个具体目标：1）支持多高学科的艾滋病毒研究 在当地环境中，在CFAR的四个机构中建立有影响力的团队科学； 2）到 护士和支持初级调查人员的职业发展，以增加 下一代艾滋病毒研究人员； 3）专门为MMC研究者提供HIV研究机会， 包括与CFAR的调查人员和资源的参与以及利用团队科学；和4） 为了继续对以HIV为重点的社区参与研究的研究遍及CFAR， 并重点是结束流行病。